RESUMO
The present work aimed to evaluate the effects promoted by a phase of compensatory growth on metabolic turnover rate, digestive enzyme activity, and bacterial biota of the Pacific white shrimp Litopenaeus vannamei kept under different feeding regimes. Three treatments were evaluated as follows: 70% feed restriction during 3 (T3) and 6 (T6) days, followed by a period of feeding to satiety, and a control treatment without restriction periods. The results showed a full compensatory growth in treatments T3 and T6 by day 35 of the bioassay. A significant increase in trypsin and lipase (T6) activities was observed during compensatory growth, whereas specific amylase activity was significantly lower in treatment T6 compared to T3 but not significantly different from the control group. To determine the metabolic turnover rate of nitrogen in muscle tissue, an analysis of nitrogen isotope values (δ15N) at natural abundance levels was performed. At the end of the experimental period, shrimp under feed restriction had lower metabolic turnover rates and longer nitrogen residence times (t 50) in muscle tissue, as compared to individuals in the control treatment. Regarding the changes in the bacterial communities in shrimp gut, no significant differences were observed at the phylum level, with Proteobacteria being the most abundant bacteria, followed by Actinobacteria. At family taxa level, Rhodobacteraceae presented the highest relative abundance in all treatments, whereas a decrease in Vibrionaceae was observed in treatments T3 and T6 when compared to control shrimps during compensatory growth. At the genus level, a decrease in Celeribacter, Catenococcus, and Epibacterium, and an increase in Ruegeria and Shimia, were identified in shrimp subjected to feed restriction when compared to control organisms during compensatory growth (day 14). At the end of the experimental period, the evaluated parameters showed similar results as those observed in the control treatment, suggesting a normalization of the metabolism and the physiological state. The present findings contribute to a better understanding on the physiological effects produced during compensatory growth in shrimp, which in turn could assist in the development of improved feeding strategies in benefit of the aquaculture industry.
Assuntos
Bactérias , Penaeidae , Humanos , Animais , Bactérias/metabolismo , Fármacos Gastrointestinais , Lipase/metabolismo , NitrogênioRESUMO
La esclerosis tuberosa (ET) es una enfermedad genética, autosómica dominante que tiene expresividad variable y que se caracteriza por la presencia de hamartomas en múltiples órganos de diferentes sistemas (piel, cerebro y corazón). Es causada por mutaciones en los genes TSC1 locus 9q34 y TSC2 locus 16p13. Tiene una prevalencia de 1 en cada 5000 a 10000 recién nacidos vivos. Se reporta el caso de una gestante y su feto con diagnóstico de ET. Se observaron masas en corazón y cerebro en el feto. El examen físico exhaustivo de la embarazada mostró criterios mayores de la enfermedad. Los hallazgos del diagnóstico prenatal fueron confirmados en el recién nacido. Se contribuye a la construcción de datos epidemiológicos latinoamericanos, y se aporta un plan de manejo a fetos, embarazadas y recién nacidos con ET.
Tuberous Sclerosis (TS) is a genetic disorder, exhibits an autosomal dominant inheritance pattern with variable expression, characterized by the presence of hamartomas in multiple organs of various systems (skin, brain and hearth). It is caused by mutations in genes TSC1 loci 9q34 and TSC2 loci 16p13. It has a prevalence of 1 in every 5000 to 10000 live births. We report a case of a pregnant and her fetus with diagnosis of TS. Masses in heart and brain in the fetus were observed, the thorough physical examination of pregnant also showed major criteria of the disease. Prenatal diagnosis findings were confirmed in the newborn. The objective is contribute to the construction of Latin American epidemiological data, a management plan for fetuses, pregnant women and infants with TS is provided.
Assuntos
Humanos , Masculino , Feminino , Gravidez , Recém-Nascido , Adulto , Diagnóstico Pré-Natal/métodos , Esclerose Tuberosa/diagnóstico por imagem , Rabdomioma/diagnóstico por imagem , Neoplasias Encefálicas/diagnóstico por imagem , Ecocardiografia , Ultrassonografia Pré-Natal , Angiomiolipoma/diagnóstico por imagem , Coração Fetal/diagnóstico por imagem , Neoplasias Cardíacas/diagnóstico por imagemRESUMO
Congenital varicella syndrome encompasses a broad spectrum of malformations present in children of mothers who developed chickenpox during the first 20 weeks of gestation. We report a case of a monochorionic diamniotic twin pregnancy, with maternal exposure to chickenpox during the thirteenth week of gestation, which produced one symptomatic and one healthy child.
RESUMO
La conjuntivitis alérgica es una de las causas más comunes de consulta externa en oftalmología y tiene una muy alta relación con las reacciones alérgicas sistémicas. La fisiopatología de las reacciones de hipersensibilidad nos hace entender los cuadros clínicos característicos de esta patología y sus diferentes grados de severidad. El diagnostico diferencial es amplio, sin embargo hay claves diagnosticas que nos orientan rápidamente al diagnostico correcto. El tratamiento se enfoca en las medidas farmacológicas y no farmacológicas, utilizándolas en conjunto para disminuir la recurrencia del cuadro y prevenir secuelas visuales.
Ocular allergies are the one of the most common pathologies in ophthalmology and have high association with systemic allergic reactions. The physiopathology of the hypersensitivity reactions make us understand the different manifestations and severity of this pathology. Differential diagnosis is wide but many diagnostic clues guide us quickly to the right disease. Treatment basis are pharmacological and non pharmacological, using them together to prevent relapses and visual sequelae.
Assuntos
Conjuntivite , Conjuntivite Alérgica , Hipersensibilidade , MastócitosRESUMO
PURPOSE: To report a case of late bacterial keratitis after intrastromal corneal ring segments (ICRSs; Ferrara ring; Ferrara Ophthalmics, Belo Horizonte, Brazil). METHODS: Review the clinical findings in a 42-year-old woman with bilateral keratoconus who underwent implantation of Ferrara ring segments in her left eye and 4 months later presented with corneal infiltrates and hypopyon. Bacterial staining, culture, and antibiotic sensitivities were done. Medical treatment and rings explantation were performed. RESULTS: The cultures revealed growth of vancomycin-oxacillin sensible coagulase-positive Staphylococcus aureus. Treatment with topical moxifloxacin, topical imipenem, and systemic intravenous and topical vancomycin was kept for two weeks. Corneal inflammation and hypopyon resolved, leaving a minimal residual leucoma. CONCLUSIONS: Infectious keratitis is an uncommon complication of ICRS and it may be late in presentation, even months after implantation. Importance of patient education about alarm symptoms and the need for long-term close postoperative follow-up cannot be underestimated. If a change in surgical technique, i.e., suturing the incision, has an influence in this complication's incidence, it will require further studies.
Assuntos
Substância Própria/cirurgia , Úlcera da Córnea/microbiologia , Infecções Oculares Bacterianas/microbiologia , Ceratocone/cirurgia , Complicações Pós-Operatórias , Próteses e Implantes , Infecções Estafilocócicas/microbiologia , Adulto , Antibacterianos/uso terapêutico , Compostos Aza/uso terapêutico , Úlcera da Córnea/diagnóstico , Úlcera da Córnea/tratamento farmacológico , Quimioterapia Combinada , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/tratamento farmacológico , Feminino , Fluoroquinolonas , Humanos , Imipenem/uso terapêutico , Testes de Sensibilidade Microbiana , Moxifloxacina , Implantação de Prótese , Quinolinas/uso terapêutico , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/tratamento farmacológico , Vancomicina/uso terapêuticoRESUMO
En un estudio propectivo randomizado se estudian 60 pacientes obesas divididas en grupos de 20 pacientes de acuerdo con el porcentaje de obesidad en: 20-29 por ciento; 30-39 por ciento y 40 por ciento de sobrepeso. A la mitad de los pacientes se les instaura dieta similar a la usada en la diabética gestacional. La otra mitad se le administra dieta libre y sirve de control. Se determina peso del R.N, morbimortalidad fetal y materna. No se encontró diferencia en el peso del R.N; la incidencia de macrosómicos es similar en ambos grupos (13.3 por ciento). No se presentó mortalidad materna ni fetal en ninguno de los grupos. La incidencia de césareas por fetos grandes para la edad gestacional en el grupo estudio vs. grupo control fue de 38.4 por ciento vs. 53.8 por ciento y los antecedentes de familiares de diabetes son más frecuentes a medida que aumenta la obesidad. En los tres grupos de obesidad del grupo estudio se encontró correlación entre el peso del RN y la edad gestacional, contrario a lo encontrado con el grupo control. Se concluye que aunque en este estudio no hay diferencia en la morbimortalidad materna-fetal, ni en el peso del RN, con relación a recibir a recibir o no dieta, ésta es benéfica en la regulación del metabolismo energético fetal que lo lleva a adquirir uan relación normal del creciemiento fetal