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1.
Nat Prod Res ; 19(7): 661-6, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16076635

RESUMO

Aryltetralone lignans bearing methylenedioxy groups (1a-b; 2a-b) were isolated from seeds of Virola sebifera. Their antioxidant activities were evaluated by inhibition of lipid peroxidation as indicated by TBARS and chemiluminescence emission (CL) assays. The lignan 1c, 'having a 2'-hydroxy-4',5'-methylenedioxyphenyl group, was the most active compound with TBARS/CL Q 1/2 values of 0.89 and 0.10 microg/mL, respectively. The catechol derivatives 3 and 4, obtained by demethylenation of lignans 1a and 2a, were of similar activity to 1c, and all were much more effective as antioxidants than alpha-tocopherol.


Assuntos
Antioxidantes/farmacologia , Lignanas/química , Myristicaceae/química , Lignanas/farmacologia , Sementes/química
2.
In. Oga, Seizi. Fundamentos de toxicologia. Sao Paulo, Atheneu, 1996. p.59-70, tab, graf.
Monografia em Português | LILACS | ID: lil-182891
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