RESUMO
The "In vitro" antifungal activity of ozonized sunflower oil (Bioperoxoil®) was tested on 101 samples of yeasts originating from onychomycosis using the disk diffusion method. The oil was efficacious against several clinical fungal strains: Candida parapsilosis, Candida albicans, Trichosporonasahii, Candida tropicalis and Candida guilliermondii.(AU)
Assuntos
Humanos , Óleos/análise , Helianthus , Antifúngicos/química , Leveduras , Ozônio/uso terapêuticoRESUMO
The "In vitro" antifungal activity of ozonized sunflower oil (Bioperoxoil®) was tested on 101 samples of yeasts originating from onychomycosis using the disk diffusion method. The oil was efficacious against several clinical fungal strains: Candida parapsilosis, Candida albicans, Trichosporonasahii, Candida tropicalis and Candida guilliermondii.
Assuntos
Antifúngicos/análise , Técnicas In Vitro , Micoses , Onicomicose , Óleos de Plantas/análise , Leveduras , Helianthus , Métodos , MétodosRESUMO
The "in vitro" antifungal activity of ozonized sunflower oil (Bioperoxoil®) was tested on 101 samples of yeasts originating from onychomycosis using the disk diffusion method. The oil was efficacious against several clinical fungal strains: Candida parapsilosis, Candida albicans, Trichosporon asahii, Candida tropicalis and Candida guilliermondii.
RESUMO
The natural habitat of Tritirachium oryzae is soil and decaying plant material. It is also an insect pathogen. As a human pathogen, it has been reported as a cause of corneal ulcers and otomycosis. The case of a 4-year-old infant is reported with Tritirachium oryzae infection of the scalp. Diagnosis was established by direct mycological study and culture that showed Tritirachium oryzae as the only agent in a pure culture. The topical treatment involved an antifungal medication to a complete cure. We report the first case of scalp dermatomycosis due to Tritirachium oryzae infection, illustrating a novel clinical manifestation.
Assuntos
Ascomicetos/isolamento & purificação , Micoses/diagnóstico , Couro Cabeludo/microbiologia , Administração Tópica , Antifúngicos/administração & dosagem , Antifúngicos/uso terapêutico , Ascomicetos/crescimento & desenvolvimento , Pré-Escolar , Feminino , Humanos , Micoses/microbiologia , Resultado do TratamentoRESUMO
The present work aimed to determine the oral microbiotic composition of snakes from São José do Rio Preto city, São Paulo State, Brazil. Ten snake species, comprising the families Boidae, Colubridae, Elapidae and Viperidae, were submited to microbiological examination of their oral cavity, which indicated positivity for all buccal samples. Gram-negative bacilli, gram-negative cocci bacilli, grambacilli and gram-positive cocci were isolated from the snakes. Among isolated bacterium species, the occurrence of coagulase-negative staphylococci in the buccal cavity of Crotalus durissus (Viperiade), Eunectes murinus (Boidae), Mastigodryas bifossatus (Colubridae) and Bacillus subtilis, common to oral cavity of Bothrops alternatus (Viperidae) and Phalotris mertensi (Colubridae), was detected. It was observed higher diversity of isolated bacteria from the oral cavity of Micrurus frontalis (Elapidae) and Philodryas nattereri (Colubridae), as well as the prevalence of gram-positive baccillus and gram-positive cocci. The composition of the oral microbiota of the studied snakes, with or without inoculating fangs, is diverse and also related to the formation of abscesses at the bite site in the victims of the ophidian accidents, and to pathogenic processes in the snakes that host these microorganisms
Assuntos
Animais , Boidae , Bactérias/isolamento & purificação , Boca/microbiologia , Colubridae , Viperidae , BrasilRESUMO
OBJECTIVES: To report the experience in the treatment of Hodgkins lymphoma in children at Hospital das Clínicas, UFMG, Brazil.METHODS: 31 children with Hodgkins lymphoma were retrospectively followed up from 1983 to 1999. Fifteen children were treated according to HD-85, a protocol based on German-Austrian studies; the 16 remaining children were treated otherwise.RESULTS: The age at diagnosis varied from 3 to 15 years (median 9 years). There were 28 male patients. The follow-up period ranged from 2 months to 16 years (median 3 years and 7 months). Mixed cellularity was the predominant (61%) histological subtype; 58% had advanced disease (stages III or IV) at diagnosis. Staging abdominal surgery was necessary in 61%. No reduction in the frequency of staging surgeries was observed after starting standardized HD-85 protocol in 1994. Herpes simplex and zoster infections were the most common complications. The estimated probability of disease-free survival (DFS) was 55.6%-/+11.7% at 5 years. Overall survival probability was 96.5%-/+3.5%. No difference in DFS was apparent between children treated with HD-85 and those treated otherwise.CONCLUSIONS: The overall results in DFS are worse than those reported in the literature. The predominance of mixed cellularity subtype, and early age and advanced disease at diagnosis are commonly reported in developing countries and do not fully explain the observed results. A longer follow-up is necessary to evaluate the influence of treatment standardization on the outcome of these children.