RESUMO
Objective: To determine the trends in the incidence of HIV infection in the Atacama region, Chile, according to age and sex, for the 2010-2017 period. Material and Methods: Analysis from the database of confirmed HIV-positive diagnosis cases. HIV incidence rates were made up from confirmed HIV cases adjusted by year, age, and sex, with population denominators from the INE. General and specific trend analysis was performed using regression equations. Results: The groups with the highest incidence of HIV infection were: 20-29 years, 30-39 years, and 40-49 years. The analysis of the curve and its general trend showed that the growth curve of the 20-29 years group is the strongest. Adjusting for sex, it was observed that, in men, the 20-29 years group has the strongest growth and growth forecast of all groups, followed by men aged 50-59 years. In the case of women, the 50-59 and 60-69 age groups are the fastest growing, however, it is a slower growth in relation to the men's group. Conclusions: Chile has one of the fastest growing HIV epidemics in the world. We estimate that the most incidental groups are linked to the mining population, which denotes the importance of the relationship between mining activity and the high incidence of HIV infection. The results suggest the need for prevention and early detection of the sources of HIV infection and the need to adapt strategies in this population. It is necessary to close the gap of HIV-positive people who do not know their health status, in order to stop the spread of HIV among miners and in the communities surrounding the mining industry.
Objetivo: Determinar las tendencias de la incidencia del contagio por VIH en la región de Atacama, Chile, según edad y sexo, para el período 2010-2017. Materiales y Métodos: Análisis desde la base de datos de casos confirmados de diagnóstico de VIH positivos. Las tasas de incidencia de VIH se confeccionaron a partir de los casos confirmados por VIH ajustados por año, edad y sexo, con denominadores poblacionales del INE. Se realizó un análisis de tendencia general y específica mediante ecuaciones de regresión. Resultados: Los grupos con mayor incidencia de infección por VIH fueron: 20-29 años, 3039 años y 40-49 años. El análisis de la curva y su tendencia general mostró que la curva de crecimiento del grupo 20-29 años es la más fuerte. Ajustando por sexo, se observó que en los hombres del grupo 20-29 años el crecimiento y el pronóstico de crecimiento es el más fuerte de todos los grupos, seguido por hombres de 50-59 años. En el caso de las mujeres, los grupos más incidentes fueron 50-59 y 60-69 años. Conclusiones: Chile tiene una de las epidemias de VIH de más rápido crecimiento en el mundo. Estimamos que los grupos más incidentes están vinculados a la población minera, lo que denota la importancia de la relación existente entre la actividad minera y la alta incidencia del contagio por VIH. Los resultados sugieren la necesidad de prevenir y pesquisar tempranamente las fuentes de infección por VIH y adaptar las estrategias en esta población.
RESUMO
Samples were collected from 128 symptomatic humans, 83 dogs, 49 mice, and 20 rats (Rattus rattus: 16; Rattus norvegicus: 4) in neighborhoods where human leptospirosis have been reported within the principal sea-port city of Colombia. Seroprevalences were assessed against 19 pathogenic, 1 intermediate pathogenic, and 1 saprophytic Leptospira serogroups. Pathogenic Leptospira were confirmed using conventional Leptospira-specific polymerase chain-reaction and pulsed-field gel electrophoresis analysis was used for serovar identification. Seroprevalences of 20.4%, 12.5%, 25.0%, 22.9%, and 12.4% were obtained against one to seven different serogroups in mice, R. rattus, R. norvegicus, dogs, and humans, respectively. The DNA was confirmed to be from pathogenic Leptospira by detecting the lipL32 gene in 12.5%, 3.7%, and 0.03% of the R. rattus, dog, and human samples, respectively. The first genetically typed Colombian isolate was obtained from a rat and identified as Leptospira interrogans serovar Icterohaemorrhagiae/Copenhageni.