1.
Chem Biodivers
; 8(6): 1098-111, 2011 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21674782
RESUMO
Analogs of curcuphenol/elvirol, naturally occurring bisabolane sesquiterpenes, were prepared in six steps from alkyl-α-tetralones employing an aromatization reaction of cyclic dienone precursors and olefination of the key aldehyde intermediates. The in vitro antifungal activities of 6a, 6b, 6d, and 6g are also reported.
Assuntos
Aldeídos/química , Antifúngicos/química , Sesquiterpenos/química , Antifúngicos/síntese química , Antifúngicos/farmacologia , Ciclização , Testes de Sensibilidade Microbiana , Sesquiterpenos/síntese química , Sesquiterpenos/farmacologia
2.
Chem Biodivers
; 1(6): 854-61, 2004 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17191885
RESUMO
Enantiomerically pure compounds as precursors for the synthesis of hydroxylated derivatives of artemisinin/arteether have been prepared from (+)-(S)-carvone and (+)-car-2-ene.