RESUMO

Lipoteichoic acid (LTA), present in Gram-positive microorganisms, has physiochemical characteristics that allow it to act as an immunogen. Due to polymicrobial characteristics of root canal infections, LTA can participate in the development of periapical disease. The reaction of the rat subcutaneous tissue to Teflon tube implants, filled with Fibrinol soaked in lipoteichoic acid (concentration of 150 microg/ml), was observed. Lipoteichoic acid provoked an inflammatory tissue reaction.

Assuntos

Inflamação/induzido quimicamente , Lipopolissacarídeos/farmacologia , Ácidos Teicoicos/farmacologia , Animais , Bactérias Anaeróbias/química , Doenças da Polpa Dentária/microbiologia , Enterococcus faecalis/química , Ativação de Neutrófilo , Ratos , Ratos Wistar , Tela Subcutânea/efeitos dos fármacos