RESUMO

The presence of gram-negative bacteria in the oral cavity is an undesirable occurrence in patients undergoing chemotherapy. Our aim was to investigate the antibacterial effect of 0.12% chlorhexidine mouthwash in chemotherapypatients with a randomized, double-blind, placebo-controlled trial. There were no significant differences between oral colonization rates; there may be local factors that interfere with chlorhexidine activity.

Assuntos

Antibacterianos/uso terapêutico , Clorexidina/uso terapêutico , Bactérias Gram-Negativas/efeitos dos fármacos , Antissépticos Bucais/uso terapêutico , Adolescente , Adulto , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Boca/microbiologia , Adulto Jovem