RESUMO
BACKGROUND: Individualization of treatment based on acne type and severity, location, disease burden, and patient preference is required to maximize efficacy, safety, and adherence to therapy. Latin American populations have unique attributes that must be considered as part of this process to improve clinical success and achieve patient goals. Acne is more common among patients with darker skin phototypes, in whom it is often associated with postinflammatory hyperpigmentation and scarring-the most important acne sequelae-potentially due to more frequent and more severe underlying inflammatory processes in this population. DISCUSSION: These data argue for an early and proactive approach to managing acne in these patients with agents that target the inflammatory processes that underlie acne and its sequelae. As a class, retinoids offer a spectrum of activity that may be useful in addressing the unique needs of Latin American populations. CONCLUSION: Trifarotene, a novel, selective retinoid, has been evaluated in relevant patient populations.
Assuntos
Acne Vulgar , Fármacos Dermatológicos , Humanos , América Latina/epidemiologia , Retinoides/efeitos adversos , Acne Vulgar/tratamento farmacológico , Acne Vulgar/complicações , Cicatriz/complicações , Resultado do Tratamento , Fármacos Dermatológicos/efeitos adversosRESUMO
El epitelioma basocelular (EB) constituye la neoplasia cutánea más frecuente. El 85-90 por ciento se localiza en regiones fotoexpuestas, atribuyéndosele a las radiaciones UV un rol preponderante en su etiopatogenia. Se presenta una paciente que desarrolló un epitelioma basocelular en la región perianal. Se destaca la localización poco frecuente, otros factores etiopatogénicos y diagnósticos diferenciales
Assuntos
Humanos , Feminino , Idoso , Neoplasias do Ânus/diagnóstico , Carcinoma Basocelular/diagnóstico , Diagnóstico Diferencial , Neoplasias do Ânus/classificação , Neoplasias do Ânus/patologia , Carcinoma Basocelular/patologiaRESUMO
El epitelioma basocelular (EB) constituye la neoplasia cutánea más frecuente. El 85-90 por ciento se localiza en regiones fotoexpuestas, atribuyéndosele a las radiaciones UV un rol preponderante en su etiopatogenia. Se presenta una paciente que desarrolló un epitelioma basocelular en la región perianal. Se destaca la localización poco frecuente, otros factores etiopatogénicos y diagnósticos diferenciales (AU)