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INTRODUCTION: Obesity is a pandemic in Mexico. The purpose of this study was to assess the environmental factors that have the strongest association with obesity and abdominal obesity among adults in Tijuana. METHODS: Four neighborhoods differing in socioeconomic status were chosen. A questionnaire for weekly walking, social cohesion, satisfaction with their community, weekly income, and convenience store, education, family income, crime safety, pedestrian safety, street connectivity, walking/cycling facilities, and sociodemographic characteristics was administered. Weight, height, and waist circumference were measured. Univariate and multivariate binomial logistic regressions were conducted. RESULTS: Three hundred and twenty-two (322) individuals, 70% females with a mean age of 39 years, were assessed. The prevalence of obesity and abdominal obesity was 27% and 43.5% respectively. The odds ratio for obesity and abdominal obesity among those living in the lowest-income neighborhood was 2.4 and 7.8 respectively, compared with those living in a middle-class neighborhood. CONCLUSIONS: Residence in a low-income neighborhood was a predictor for obesity.

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The purpose of the present study was to assess the glycaemic index (GI) and glycaemic load (GL) of different mixed meals traditionally consumed in Mexico. GI was measured for three meals (Pozole, Molletes and Mole), using glucose as a reference in 12 college student subjects. Mole (p = 0.002), Molletes (p = 0.043) and Pozole (p = 0.016) showed a lower IAUC than glucose. However, there was not difference between meals. Higher GI and GL levels were observed than the estimated GI using as reference the International Table of Atkinson et al. (2008. Diabetes Care 31(12):2281-2283). Since food ingredients vary among Mexican regions, it is recommended to assess the GI and GL of mixed meals according to the cooking habits of each region.

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Introduction: Obesity has become a public health problem. The increment in energy intake and the reduction of caloric expenditure as a result of sedentary lifestyles promotes a positive energetic balance resulting in the increase of fat deposits. In response to this, the prescription of pharmacological treatments has also increased. Objective: To evaluate the long-term weight loss effectiveness of pharmacological treatments. Methodology: A systematic review was conducted on randomized clinical trials registered in Pub Med, Scielo, and EBSCOHOST from January 1st 1999 to December 31st 2008, including those with an intervention program with orlistat, sibutramine, and rimonabant equal or greater to two years. Two hundred and twelve articles were identified, 201 studies were excluded, and eleven were analyzed; seven from orlistat, two from sibutramine, and two from rimonabant. Information of design, intervention time, number of patients, age, body mass index and weight loss, difference between the intervention group versus the placebo, significance level, and methodological quality were obtained. Main findings: The percentage of weight loss with orlistat ranged between 5 and 12%, the mean weight loss was 8 kg, and a difference between IG vs. placebo of 3.7 kg. Weight loss with sibutramine ranged between 4 and 10%, the mean weight loss was 7.4 kg and a difference between the intervention group versus placebo was 5.5 kg. Weight loss with rimonabant was 7% with a mean weight loss of 7.3 kg, and the difference compared with the placebo was 4.4 kg. Conclusions: Weight loss with pharmacotherapy is modest; weight regain after interruption of treatment, adverse effects, costs and lack of evidence related to long-term morbi-mortality, do not justify the generalized use of pharmacological treatment of obesity.

Introducción: La obesidad se ha convertido en un problema de salud pública. El incremento en el consumo energético y el menor gasto calórico, debido al sedentarismo, promueve un balance energético positivo que se traduce en el incremento de depósitos grasos. En respuesta al incremento de la obesidad se ha aumentado la prescripción del tratamiento farmacológico. Objetivo: Evaluar la efectividad del tratamiento farmacológico sobre la pérdida de peso con un seguimiento igual o mayor a 2 años. Metodologia: Se realizó una revisión sistemática de estudios aleatorios registrados en PubMed, Scielo y EBSCOHOST del 1 enero de 1999 al 31 de diciembre del 2008 y se seleccionaron aquellos con un período de intervención mayor o igual a dos años con orlistat (Or), sibutramina (Sib) y rimonabant (Ri). Se identificaron 212 artículos, se excluyeron 201 estudios y se analizaron once, siete de Or, dos de Sib y dos de Ri. Se obtuvo información del diseño del estudio, el tiempo de intervención, el número de participantes, la edad, el índice de masa corporal (IMC), la pérdida de peso, la diferencia entre GI vs placebo, el nivel de significancia y la calidad metodológica. Hallazgos: El porcentaje de pérdida de peso al final de la intervención con orlistat osciló entre 5% y 12%, un promedio de pérdida de 8 kg y una diferencia entre GI vs placebo de 3.7 kg. Con sibutramina, entre 4% y 10%, el promedio de pérdida de peso fue de 7.4 kg y diferencia entre GI vs placebo de 5.5kg. Con rimonabant, se observó en promedio 7.3 kg de pérdida de peso a los 2 años, y una diferencia con el grupo placebo de 4.4 kg. El porcentaje de pérdida de peso fue de 7%. Conclusiones: La pérdida de peso con farmacoterapia es modesta, la recuperación posterior a la interrupción del tratamiento, los efectos adversos, el costo y la falta de evidencias sobre morbi-mortalidad a largo plazo, no justifican el tratamiento farmacológico generalizado de la obesidad.

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BACKGROUND: Overweight and obesity have dramatically increased in recent years. In 2006, the prevalence of overweight and obesity among 6- to 12-year-old children was 26% in Mexico. Food advertising has shown to be a contributor to childhood obesity. The purpose of this study was to evaluate the frequency and types of food advertisements geared toward children living in Baja California. METHODS: Two local channels and three national channels, during a period of 7 h on weekday afternoons and 6 h on weekend mornings, were recorded for 7 days. A total of 235 h were recorded and analyzed. RESULTS: A total of 8299 advertisements were registered; 22% were food-related and 50% were geared toward children. The average of food-related advertisements (FRAs) per half an hour was 4, and half of them were geared toward children. During the time that children may be watching television, 50% of all FRAs were potato and corn chips, desserts and cakes, juices, sweetened cereals, candies, cookies, sweetened beverages and fast foods, which comprises a higher percentage of adult-oriented FRA (32 versus 22%). CONCLUSION: Children are systematically more exposed than adults to advertisements for high-energy-dense foods.

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