RESUMO
Objetivo: Realizar una revisión sistemática y metaanálisis que resuma el riesgo de hipoacusia de personas con diagnóstico de síndrome o enfermedades metabólicas versus aquellas sin síndrome metabólico. Material y Métodos: Siguiendo las recomendaciones PRISMA para revisión sistemática y metaanálisis, se realizaron búsquedas en 3 indexadores (PubMed, Web of Science y SciELO). Se incluyeron sólo estudios transversales que reportan asociaciones de hipoacusia con obesidad, Hipertensión; Diabetes, Dislipidemia, Colesterol, síndrome metabólico e Hiperglicemia. Las odds ratios (OR) con sus intervalos de confianza (IC) del 95% de los estudios se agruparon en un modelo de efectos aleatorios por el método de Mantel Haenszel. Con Rev Manager 5.1, se evaluó la heterogeneidad OR mediante las estadísticas I2 y Q. Resultados: 28 estudios observacionales fueron incluidos en el análisis cuantitativo. Las OR para hipoacusia prevalente fue de 1.27 (95% IC 1.07, 1.51) en obesidad, 1.97 (95% IC 1.51, 2.57) en diabetes, 1.53 (95% IC 1.31, 1.79) en hipertensión y 4.22 (95% IC 1.74, 10.20) para síndrome metabólico. Conclusiones: Los hallazgos sugieren que tanto el síndrome metabólico como algunas enfermedades como obesidad, diabetes e hipertensión podrían asociarse con el riesgo de hipoacusia, pudiendo el control de estas enfermedades atenuar este riesgo.
Introduction: Various studies have linked lifestyle and metabolic diseases to hearing loss. Research on metabolic syndrome has reported a higher prevalence of hearing loss in individuals with it than those without it. Objectives: To conduct a systematic review and meta-analysis summarizing the risk of hearing loss in people diagnosed with metabolic syndrome or diseases versus those without metabolic syndrome. Methods. Following the PRISMA recommendations for systematic review and meta-analysis, searches were conducted in PubMed, Web of Science, and SciELO. Only cross-sectional studies associate hearing loss with obesity, hypertension, Diabetes, Dyslipidemia, Cholesterol, metabolic syndrome, and Hyperglycemia. The odds ratios (OR) with their 95% confidence intervals (CI) of the studies were pooled in a random effects model using the Mantel-Haenszel method. Using Rev Manager 5.1, OR heterogeneity was assessed using the I2 and Q statistics. Results. Twenty-eight observational studies were included in the quantitative analysis. The OR for prevalent hearing loss was 1.27 (95% CI 1.07, 1.51) in obesity, 1.97 (95% CI 1.51, 2.57) in diabetes, 1.53 (95% CI 1.31, 1.79) in hypertension, and 4.22 (95% CI 1.74, 10.20) for metabolic syndrome. Conclusions. The findings suggest that both metabolic syndrome and some diseases, such as obesity, diabetes, and hypertension, could be associated with the risk of hearing loss, and control of these diseases could reduce this risk.
RESUMO
INTRODUCTION: Various studies have linked lifestyle and metabolic diseases to hearing loss. Research on metabolic syndrome has reported a higher prevalence of hearing loss in individuals with it than those without it. OBJECTIVES: To conduct a systematic review and meta-analysis summarizing the risk of hearing loss in people diagnosed with metabolic syndrome or diseases versus those without metabolic syndrome. METHODS: Following the PRISMA recommendations for systematic review and meta-analysis, searches were conducted in PubMed, Web of Science, and SciELO. Only cross-sectional studies associate hearing loss with obesity, hypertension, Diabetes, Dyslipidemia, Cholesterol, metabolic syndrome, and Hyperglycemia. The odds ratios (OR) with their 95% confidence intervals (CI) of the studies were pooled in a random effects model using the Mantel-Haenszel method. Using Rev Manager 5.1, OR heterogeneity was assessed using the I2 and Q statistics. RESULTS: Twenty-eight observational studies were included in the quantitative analysis. The OR for prevalent hearing loss was 1.27 (95% CI 1.07, 1.51) in obesity, 1.97 (95% CI 1.51, 2.57) in diabetes, 1.53 (95% CI 1.31, 1.79) in hypertension, and 4.22 (95% CI 1.74, 10.20) for metabolic syndrome. CONCLUSIONS: The findings suggest that both metabolic syndrome and some diseases, such as obesity, diabetes, and hypertension, could be associated with the risk of hearing loss, and control of these diseases could reduce this risk.