RESUMO
Background: Squamous cell carcinoma (SCC) is a malignant neoplasm of epidermal cells that exhibits keratinocyte differentiation. These neoplasms are common in dogs, cats, horses, and cattle, relatively uncommon in sheep, and rarely affect goats and pigs. There are several factors that are associated with the development of SCC, including prolonged exposure to ultraviolet light, lack of pigment in the epidermis, and sparse coating or lack of fur at the affected sites. The aim of this study was to report the occurrence of squamous cell carcinoma in a domestic pig. Case: A surgically removed nodule from the left ear of a female, light-colored, three-year-old pig, which breed was not defined, was submitted for histopathological analysis. The sample was fixed in 10% formalin, analyzed macroscopically, routinely processed for histology, sectioned at five microns and stained with hematoxylin and eosin. Additionally, anticytokeratin (AE1/AE3) and anti-vimentin immunohistochemical assays were performed. All additional information was provided by the animals owner. According to the history obtained, the animal belonged to a herd made up of five females and one boar. For four months, multiple nodules started to grow on the outer surface of the pigs ear and in many occasions exhibited ulceration and bleeding. One of the nodules was submitted for histopathology examination.[...](AU)
Assuntos
Animais , Suínos , Carcinoma de Células Escamosas/veterinária , Queratinócitos , Neoplasias de Células Escamosas/veterinária , Imuno-Histoquímica/veterináriaRESUMO
Background: Squamous cell carcinoma (SCC) is a malignant neoplasm of epidermal cells that exhibits keratinocyte differentiation. These neoplasms are common in dogs, cats, horses, and cattle, relatively uncommon in sheep, and rarely affect goats and pigs. There are several factors that are associated with the development of SCC, including prolonged exposure to ultraviolet light, lack of pigment in the epidermis, and sparse coating or lack of fur at the affected sites. The aim of this study was to report the occurrence of squamous cell carcinoma in a domestic pig. Case: A surgically removed nodule from the left ear of a female, light-colored, three-year-old pig, which breed was not defined, was submitted for histopathological analysis. The sample was fixed in 10% formalin, analyzed macroscopically, routinely processed for histology, sectioned at five microns and stained with hematoxylin and eosin. Additionally, anticytokeratin (AE1/AE3) and anti-vimentin immunohistochemical assays were performed. All additional information was provided by the animals owner. According to the history obtained, the animal belonged to a herd made up of five females and one boar. For four months, multiple nodules started to grow on the outer surface of the pigs ear and in many occasions exhibited ulceration and bleeding. One of the nodules was submitted for histopathology examination.[...]