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Endocrinol Diabetes Nutr ; 64(1): 11-17, 2017 Jan.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-28440765

RESUMO

OBJECTIVE: The theory of fetal programming suggests that low birth weight (LBW) predisposes to greater food intake and increases the chance of overweight and obesity, which are in turn associated to conditions such as metabolic syndrome (MS) and acanthosis nigricans. The study objective was to ascertain whether an association exists between MS, LBW, intake of high-calorie diets, and acanthosis nigricans in children and adolescents with overweight or obesity. MATERIAL AND METHODS: A case-control was conducted on 100 children who attended the overweight and obesity outpatient clinic of the OPD Hospital Civil de Guadalajara "Fray Antonio Alcalde". Subjects were stratified in groups with and without MS based on the criteria of the International Diabetes Federation for children aged less than 16 years. Data on LBW, intake of high-calorie diets for 24-hour dietary recalls (average 2 days a week), and acanthosis nigricans (Simone criteria) were obtained by questioning the parents. Frequencies and logistic regression were calculated using SPSS version 22. RESULTS: The results show that 82% of children and adolescents were obese and 18% overweight, and 73% had MS. MS was associated to LBW (OR: 4.83 [95% CI: 1.9-12.47]), high-calorie diets (OR:136.8 [95% CI: 7.7-2434]), and acanthosis nigricans (OR: 1872 [95% CI: 112.9-31028]). CONCLUSIONS: In children and adolescents with overweight and obesity, LBW, high-calorie diets, and acanthosis nigricans are associated to a higher probability of MS.


Assuntos
Acantose Nigricans/epidemiologia , Síndrome Metabólica/epidemiologia , Sobrepeso/epidemiologia , Efeitos Tardios da Exposição Pré-Natal , Acantose Nigricans/etiologia , Adolescente , Estudos de Casos e Controles , Criança , Pré-Escolar , Comorbidade , Dieta , Registros de Dieta , Suscetibilidade a Doenças , Escolaridade , Ingestão de Energia , Feminino , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Masculino , Síndrome Metabólica/etiologia , México/epidemiologia , Obesidade/epidemiologia , Obesidade/etiologia , Sobrepeso/etiologia , Gravidez , Prevalência
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