RESUMO
The authors reviewed the clinical records of 31 patients with carcinoma of the breast diagnosed at the Dr. Rafael Hernández Hospital in Chiriquí from January 1988 to December 1990. All the patients were women and the average age was 51.9 years. 41.9% of the patients were classified Stage 1; 29%, Stage 2; 16.1%, Stage IIIA; and 12.8%, Stage IIIB. 74% of the patients were treated with a modified radical mastectomy, radiation and hormonal therapies. Systemic cytotoxic therapy was given to 77% of the patients. Total survival 48 months after diagnosis was 83.3% in patients at Stage I; 66%, at Stage II; 40%, at Stage IIIA; and 0%, in patients at Stage IIIB
Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Neoplasias da Mama/patologia , Estadiamento de Neoplasias , Mastectomia , Metástase Linfática , Neoplasias da Mama/mortalidade , Neoplasias da Mama/cirurgia , Panamá/epidemiologia , Terapia CombinadaRESUMO
The authors reviewed the clinical records of 31 patients with carcinoma of the breast diagnosed at the Dr. Rafael Hernández Hospital in Chiriquí from January 1988 to December 1990. All the patients were women and the average age was 51.9 years. 41.9% of the patients were classified Stage 1; 29%, Stage 2; 16.1%, Stage IIIA; and 12.8%, Stage IIIB. 74% of the patients were treated with a modified radical mastectomy, radiation and hormonal therapies. Systemic cytotoxic therapy was given to 77% of the patients. Total survival 48 months after diagnosis was 83.3% in patients at Stage I; 66%, at Stage II; 40%, at Stage IIIA; and 0%, in patients at Stage IIIB.
Assuntos
Neoplasias da Mama/patologia , Adulto , Idoso , Neoplasias da Mama/mortalidade , Neoplasias da Mama/cirurgia , Terapia Combinada , Feminino , Humanos , Metástase Linfática , Mastectomia , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Panamá/epidemiologiaRESUMO
The authors present the clinical history of a 15-year-old young woman, student, from David, Chiriquí, who complained of menstrual irregularities associated with the sensation of a mass in the right iliac fossa. Exploratory laparotomy revealed a right ovarian tumor, which was totally resected. The histopathological examination showed an endodermal sinus tumor, stage one, in the right ovary. The patient received four cycles of cytotoxic i.v. therapy every 3 weeks, after surgery, with vinblastine 6 mg/m2 body surface (B.S.) on days 1 and 2, bleomycin 15 u daily for 5 days, cisplatin 20 mg/m2 B.S. daily for 5 days, plus hydration with normal saline (5 to 6 l/day). Follow up studies with abdominal and pelvic sonograms, chest x-ray, feto protein and physical examination have not shown evidence of tumor activity 36 months after diagnosis.
Assuntos
Tumor do Seio Endodérmico/patologia , Neoplasias Ovarianas/patologia , Adolescente , Terapia Combinada , Tumor do Seio Endodérmico/terapia , Feminino , Humanos , Neoplasias Ovarianas/terapia , Ovário/patologiaRESUMO
The authors present the clinical history of a 15-year-old young woman, student, from David, Chiriquí, who complained of menstrual irregularities associated with the sensation of a mass in the right iliac fossa. Exploratory laparotomy revealed a right ovarian tumor, which was totally resected. The histopathological examination showed an endodermal sinus tumor, stage one, in the right ovary. The patient received four cycles of cytotoxic i.v. therapy every 3 weeks, after surgery, with vinblastine 6 mg/m2 body surface (B.S.) on days 1 and 2, bleomycin 15 u daily for 5 days, cisplatin 20 mg/m2 B.S. daily for 5 days, plus hydration with normal saline (5 to 6 l/day). Follow up studies with abdominal and pelvic sonograms, chest x-ray, feto protein and physical examination have not shown evidence of tumor activity 36 months after diagnosis
Assuntos
Humanos , Feminino , Adolescente , Neoplasias Ovarianas/patologia , Tumor do Seio Endodérmico/patologia , Neoplasias Ovarianas/terapia , Ovário/patologia , Terapia Combinada , Tumor do Seio Endodérmico/terapiaRESUMO
The authors studied the clinical history of a male patient, 51 years old, from Puerto Armeulles, Chiriquí, with the diagnosis of breast carcinoma, III A, who was treated with simple mastectomy and systemic cytotoxic therapy, with 5 FU, Adriamycin and Cyclophosphamide at three weeks intervals, completing six cycles, followed by radiotherapy to the tumor site and the areas of lymphatic drainage, and hormonal therapy with Tamoxifen. The patient is now in good health and without clinical, radiographic or enzymatic evidence of tumoral activity, twelve months after the diagnosis.
Assuntos
Neoplasias da Mama , Carcinoma , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/terapia , Carcinoma/diagnóstico , Carcinoma/terapia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The clinical evolution of one patient with primary mucinous adenocarcinoma of the left ovary with "ring seal cells" is studied. The patient was surgically treated with total hysterectomy, left salpingooferectomy and peritoneal washing; and medically treated with intravenous systemic citotoxic Cis-platin, Adriamycin and Cyclophosphamide. Twelve month later she was feeling in good health and her physical examination was normal.
Assuntos
Adenocarcinoma Mucinoso/patologia , Neoplasias Ovarianas/patologia , Adulto , Feminino , HumanosRESUMO
The clinical history of a 57 y/o female who had breast cancer diagnosed at 40 years of age and who was treated with right radical mastectomy followed by irradiation of the right chest and adjacent lymphatics is presented. Recurrences of the breast cancer were treated with combination chemotherapy. Eighteen years after the original diagnosis and irradiation she presented with a new primary tumor of a different histologic type in the site of the prior irradiation. This tumors had an extremely aggressive, fatal course.
Assuntos
Neoplasias Primárias Múltiplas/etiologia , Neoplasias Induzidas por Radiação/etiologia , Sarcoma/etiologia , Neoplasias de Tecidos Moles/etiologia , Neoplasias Torácicas/etiologia , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
The authors study the relation seen between the histopathology and the race of patients with Hodgkin's disease diagnosed in Chiriqui, province of Panama and the findings in patients seen in fully developed and underdeveloped countries and of many colored race. They also noted that the greatest incidence of the disease was seen in patients between 10 and 30 years of age and those more than 60 years of age.