RESUMO

Strain of avian septicemic E. coli were examined for association among the determinants of drug resistance, the genes for aerobactin production and virulence. In conjugation experiments, a single plasmid (100 Md) from a strain of septicemic E. coli (UEL 29) transferred to E. coli K12 pathogenicity for 1-day old chicks plus resistance to streptomycin and the ability to produce aerobactin and colicin. Additional evidence for the association of R-plasmid and the production of aerobactin, colicin, resistance to sulfadiazine and pathogenicity was obtained by disassociation when all traits were lost simultaneously. These data provide additional evidence for the importance of the aerobactin system for the pathogenicity of avian E. coli

Assuntos

Animais , Galinhas , Infecções por Escherichia coli/veterinária , Escherichia coli/patogenicidade , Código Genético , Ácidos Hidroxâmicos/metabolismo , Plasmídeos , Doenças das Aves Domésticas/microbiologia , Sepse/veterinária , Colicinas/biossíntese , DNA Bacteriano/análise , Resistência Microbiana a Medicamentos/genética , Eletroforese em Gel de Ágar , Infecções por Escherichia coli/microbiologia , Escherichia coli/genética , Genes Bacterianos , Peso Molecular , Fatores R , Sepse/microbiologia , Estreptomicina , Sulfadiazina , Virulência