RESUMO
Serum and urine analytes were compared between adult wild-caught owl monkeys (Aotus nancymae) and adult wild-caught squirrel monkeys (Saimiri peruviensis) to determine if normative clinical pathology data were similar. An objective of the study was to confirm that species of neotropical primates are distinct with regard to physiologic parameters, and should not be considered interchangeable in biomedical research. Significant differences (P < 0.05) were noted in many serum and urine analytes between the two groups. The results suggest that reference data for wild-caught owl monkeys are not applicable to squirrel monkeys, and the differences are sufficiently large to be of clinical significance. These findings illuminate the diversity among species of neotropical primates.
Assuntos
Aotus trivirgatus/sangue , Saimiri/sangue , Animais , Animais Selvagens , Aotus trivirgatus/urina , Análise Química do Sangue/veterinária , Proteínas Sanguíneas/análise , Eletrólitos/sangue , Eletrólitos/urina , Peru , Proteinúria , Saimiri/urina , Especificidade da Espécie , Manejo de Espécimes/instrumentação , Manejo de Espécimes/métodos , Manejo de Espécimes/veterinária , Urinálise/veterináriaRESUMO
Blood samples from 35 wild-caught owl monkeys (Aotus vociferans, karyotype V) were analyzed to estimate reference intervals of hematologic variables for the species. Findings indicated that distributions were abnormal for leukocytes, neutrophils, eosinophils, basophils, and monocytes. Statistically significant sex differences, too small to be of clinical importance, were found in values for mean cell hemoglobin concentration, leukocytes, and basophils. Reference intervals for the hematologic variables were calculated by the nonparametric percentile estimation method. Comparison of hematologic reference values for wild-caught A. vociferans with those of A. nancymae revealed statistically significant differences for packed cell volume, mean cell volume, leukocytes, eosinophils, basophils, and platelets. These differences also appeared too small to be of clinical significance.
Assuntos
Aotidae/sangue , Contagem de Células Sanguíneas/veterinária , Índices de Eritrócitos/veterinária , Hemoglobinas/análise , Animais , Aotidae/genética , Contagem de Eritrócitos/veterinária , Feminino , Cariotipagem/veterinária , Contagem de Leucócitos/veterinária , Masculino , Contagem de Plaquetas/veterinária , Valores de Referência , Caracteres SexuaisRESUMO
Impaired renal function was observed in sixteen Aotus nancymai 25 and 3 months following infection with the Uganda Palo Alto strain of Plasmodium falciparum. Decrease were noted in the clearance of endogenous creatinine, creatinine excretion, and urine volume while increases were observed in serum urea nitrogen, urine protein, urine potassium, fractional excretion of phosphorus and potassium, and activities of urinary enzymes. The results were suggestive of glomerulonephropathy and chronic renal disease.
Assuntos
Aotus trivirgatus/parasitologia , Rim/fisiopatologia , Malária Falciparum/fisiopatologia , Animais , Sangue/parasitologia , Creatinina/metabolismo , Eletrólitos/metabolismo , Enzimas/urina , Feminino , Taxa de Filtração Glomerular , Glomerulonefrite Membranoproliferativa/etiologia , Glomerulonefrite Membranoproliferativa/urina , Testes de Função Renal , Malária Falciparum/complicações , Malária Falciparum/metabolismo , Malária Falciparum/parasitologia , Masculino , Nitrogênio/metabolismo , Proteinúria/etiologia , Proteinúria/urinaRESUMO
Impaired renal function was observed in sixteen Aotus nancymai 25 and 3 months following infection with the Uganda Palo Alto strain of Plasmodium falciparum. Decrease were noted in the clearance of endogenous creatinine, creatinine excretion, and urine volume while increases were observed in serum urea nitrogen, urine protein, urine potassium, fractional excretion of phosphorus and potassium, and activities of urinary enzymes. The results were suggestive of glomerulonephropathy and chronic renal disease
Assuntos
Animais , Cebidae , Rim/patologia , Plasmodium falciparumRESUMO
Four hundred and fifty wild-caught owl monkeys (Aotus nancymai) were shipped from Iquitos, Peru to Richland, Washington. Mortality and body weight changes from the time of shipment to 30 days after arrival were evaluated using age, sex, and transit time as comparison criteria. No association between mortality and sex, age, or transit time was observed. The mortality percentage from shipment to 30 days after arrival was 2.44%. Both age and transit time had a significant effect on weight changes, but sex did not. Shipping procedures are described.