RESUMO
Alport syndrome with diffuse leiomyomatosis (ASDL) is a complex combination that doesn't have a specific course of treatment. In this case report, we present a 44-year-old woman with ASDL and detail her treatment. The patient presented at the emergency room (ER) with symptoms of anemia, bronchial asthma, and abnormal uterine bleeding (AUB). The patient had diffuse myomas in different areas of her body, including the esophagus and genital tract. She was treated by a multidisciplinary team that included members from the hematology/oncology, pulmonary, interventional radiology, anesthesia, surgery, and gynecology services. A physician from interventional radiology performed an embolization of the uterine arteries to treat the patient's AUB. Surgery was done in May 2011 to remove the esophageal leiomyomas to improve her pulmonary function. Surgery included a distal esophagectomy, a proximal gastrostomy, and the resection of the leiomyomatous mass. In order to shrink the tumor in her genito pelvic region so that it could be extirpated with the highest likelihood of success, the patient was treated with gonadotropin-releasing hormone agonist (leuprolide acetate, 3.75 mg/month for 4 months). In May 2012, the patient had a total abdominal hysterectomy (TAH), with a bilateral salpingo-ophorectomy (BSO), the excision of a leiomyoma, and a posterior colporrhaphy.
Assuntos
Leiomiomatose/cirurgia , Nefrite Hereditária/cirurgia , Adulto , Antineoplásicos Hormonais/uso terapêutico , Administração de Caso , Criança , Terapia Combinada , Embolização Terapêutica , Neoplasias Esofágicas/genética , Neoplasias Esofágicas/cirurgia , Esofagectomia , Feminino , Gastrostomia , Neoplasias dos Genitais Femininos/tratamento farmacológico , Neoplasias dos Genitais Femininos/genética , Neoplasias dos Genitais Femininos/cirurgia , Neoplasias dos Genitais Femininos/terapia , Humanos , Histerectomia , Leuprolida/uso terapêutico , Masculino , Ovariectomia , Equipe de Assistência ao Paciente , Radiografia IntervencionistaRESUMO
Three cases of cutaneous loxoscelism in patients under two years of age from Valdivia are described. Clinical and epidemiological aspects of loxoscelism are commented
Assuntos
Humanos , Feminino , Recém-Nascido , Lactente , Dermatopatias/epidemiologia , Picada de Aranha/epidemiologia , Chile/epidemiologia , Diagnóstico Diferencial , Dermatopatias/diagnóstico , Picada de Aranha/diagnósticoRESUMO
Se comunican cinco casos detectados en los últimos 3 añosde infecciones sistémicas producidas por H.Influenzae resistentes a ampicilina ycloramfenicol, en el Servicio de Pediatría del Hospital Reginal de Valdivia
Assuntos
Humanos , Masculino , Feminino , Lactente , Infecções por Haemophilus/tratamento farmacológico , Haemophilus influenzae/efeitos dos fármacos , Resistência a Ampicilina , Resistência ao CloranfenicolRESUMO
Se presentan los hallazgos de biopsia cerebral realizada en una menor de 2 años de edad, con evidencias clínicas de una encefalitis aguda grave. La biopsia se efectuó en el lóbulo temporal derecho basado en la signología clínica de focalización neurológica y la TAC que demostró mayor compromiso en áreas temporales. Mediante microscopía electrónica se visualizaron múltiples partículas virales intranucleares morfológicamente idénticas al virus herpes simplex. A través del método peroxidasa anti peroxidasa (PAP) se observó una marcada positividad para herpes simplex tipo II. Se realizó tratamiento antiviral con Aciclovir a partir del 6º día de enfermedad. Sobrevivió con grandes secuelas neurológicas