RESUMO
OBJECTIVE: This study aims to compare breast density between two mammograms in women with premature ovarian failure (POF). METHODS: A cohort study evaluated 56 women with POF. Two mammograms performed at least 2 years apart were analyzed. Mammogram films were digitalized, and images were assessed using a computer-assisted method; the percentage of breast image that is radiologically dense is referred to as the percentage of mammographic density (PMD). Age at menarche, age at onset of POF, length of POF, length of estrogen-progestin therapy (EPT), body mass index (BMI), pregnancy, and age at the time of each mammogram were evaluated. RESULTS: The mean (SD) age at POF diagnosis was 32.35 (5.95) years. In the first mammogram, the mean (SD) age, BMI, and length of POF were 37.58 (3.72) years, 26.79 (4.86) kg/m, and 5.25 (4.61) years, respectively. EPT had been used for a mean (SD) of 2.71 (3.12) years. In the second mammogram, the mean (SD) age, BMI, and length of POF were 43.23 (4.98) years, 27.6 (5.39) kg/m, and 10.5 (5.11) years, respectively. EPT had been used for a mean (SD) of 7.25 (4.6) years. The mean (SD) interval between mammograms was 5.25 (3) years, and the mean (SD) PMD decreased from 27.78% (21.04%) to 17.53% (15.71%) (P = 0.007). Comparing PMD between women taking EPT and those not taking EPT, we observed no significant differences. In both instances, multiparous women had lower PMD than nulliparous women (P < 0.05). BMI, length of POF, and pregnancy were negatively correlated with PMD. CONCLUSIONS: Breast density in young women with POF decreases across a period of 5 years, regardless of EPT use. Further studies may elucidate how this result will correlate with decision-making in clinical therapeutics and breast cancer risk in POF.
Assuntos
Neoplasias da Mama/prevenção & controle , Mama/patologia , Insuficiência Ovariana Primária , Adulto , Estudos de Coortes , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Mamografia , Pessoa de Meia-Idade , Estudos ProspectivosRESUMO
INTRODUCTION: Stress urinary incontinence is a frequent complaint in medical offices and studies have shown that women who practice high impact sports develop its symptoms. OBJECTIVE: To evaluate the prevalence of stress urinary incontinence in women who attend gyms and perform high impact exercises and correlate it with women who do not attend gyms. METHOD: Prospective comparative study in which 488 nulliparous women of normal weight were divided into a Study Group, composed of women who attended gyms, and a Comparative Group, composed of women who did not attend gyms. Three questionnaires were used for the evaluation of stress urinary incontinence and the results of the ICIQ-SF questionnaire were used to compare the groups. RESULTS: There was a significant difference between groups on the ICIQ-SF. The average in the Study Group was 1.68 (+ 3.46) and in the Comparative Group the average was 1.02 (+ 2.69) (p = 0.006). CONCLUSION: Women who attend gym and perform high impact exercises have a higher prevalence of urinary incontinence symptoms, independent of the exercise modality, than women who do not perform any high impact exercise.