RESUMO
INTRODUCTION: Variceal hemorrhage occurs in 25 to 35% of cirrhotic patients and is associated with significant morbidity and mortality and elevated hospital costs. Endoscopic exploration of gastroesophageal varices (GEV) in cirrhotic patients increases costs and involves a certain degree of invasiveness and discomfort for patients. The association between the presence of GEV and spleen size, liver function and platelet count is controversial. The aim of this study was to determine the correlation between liver function, evaluated by Child-Pugh (Ch-P) classification, platelet count (PC) and spleen volume index (SVI) with the presence of GEV in patients with cirrhosis managed in the outpatient setting. PATIENTS AND METHOD: Sixty-eight patients were included. In all patients, a medical history was taken and biochemical tests, mode B and Doppler abdominal ultrasonography, and upper digestive video-endoscopy were performed. RESULTS: A total of 76.47% of the patients were men and 23.53% were women. The median age was 52.8 12.4 years. More than half (54.41%) of the patients were Ch-P grade A, 41.18% were grade B and 4.41% were grade C. The most frequent causes of cirrhosis were alcohol in 52.95% and hepatitis C virus in 17.65%. Esophageal varices (EV) were found in 85.29% of the patients. The median SVI was 50.5 9.2 and the median PC was 150 26 x 109/L. A correlation was found between the presence of EV, SVI >or= 45 and PC < or= 100 x 109/L (r = 0.327; p = 0.006). No correlation was found between the presence of EV and Ch-P grade A. In the multivariate analysis, only the presence of EV was associated with SVI >or= 45 (OR 7.4; 95% CI, 1.30-77.7; p = 0.02). CONCLUSION: The presence of EV in cirrhotic patients managed in the outpatient setting was correlated with SVI >or= 45 and PC Assuntos
Endoscopia Gastrointestinal
, Varizes Esofágicas e Gástricas/diagnóstico
, Cirrose Hepática/diagnóstico
, Varizes Esofágicas e Gástricas/etiologia
, Feminino
, Humanos
, Cirrose Hepática/complicações
, Testes de Função Hepática
, Masculino
, Pessoa de Meia-Idade
, Fatores de Risco
, Índice de Gravidade de Doença
, Fatores de Tempo
RESUMO
UNLABELLED: It is accepted that the practice of odontology implies a risk of BBV and HCV transmission but the study of does not. This work tries to determine the prevalence of HBv Ac and HCV Ac (by ELISA) in odontology students and whether there is any relation to the year of study and/or the presence of other risk factors. 188 students in their last three years of studies were investigated, all the participants filled out a clinical epidemiological form. 89 women (47.3%) and 99 men (52.7%), x age was 24.8. 50 (26.7%) had other risk factors. 160 (85.1%) fulfilled biosecurity norms and 40 (21.2%) had a labour accident. RESULTS: None of the analyzed sera were positive for HCV Ac (0%) and 1 was positive for HbcAc. CONCLUSION: The prevalence of HBv Ac and HCV Ac is extremely low with no relation to the year of study or any other risk factors.
Assuntos
Anticorpos Anti-Hepatite B/sangue , Anticorpos Anti-Hepatite C/sangue , Estudantes de Odontologia , Adulto , Argentina , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Transmissão de Doença Infecciosa do Paciente para o Profissional , Masculino , Fatores de Risco , Estudos SoroepidemiológicosRESUMO
It is accepted that the practice of odontology implies a risk of BBV and HCV transmission but the study of does not. This work tries to determine the prevalence of HBv Ac and HCV Ac (by ELISA) in odontology students and whether there is any relation to the year of study and/or the presence of other risk factors. 188 students in their last three years of studies were investigated, all the participants filled out a clinical epidemiological form. 89 women (47.3%) and 99 men (52.7%), x age was 24.8. 50 (26.7%) had other risk factors. 160 (85.1%) fulfilled biosecurity norms and 40 (21.2%) had a labour accident. RESULTS: None of the analyzed sera were positive for HCV Ac (0%) and 1 was positive for HbcAc. CONCLUSION: The prevalence of HBv Ac and HCV Ac is extremely low with no relation to the year of study or any other risk factors (AU)
Assuntos
Humanos , Masculino , Feminino , Hepatite B/epidemiologia , Hepatite C/epidemiologia , Estudantes de Odontologia , Hepatite B/transmissão , Hepatite C/transmissão , Prevalência , Fatores de Risco , Transmissão de Doença Infecciosa do Paciente para o Profissional , Ensaio de Imunoadsorção Enzimática , Anticorpos Anti-Hepatite B/sangue , Anticorpos Anti-Hepatite C/sangue , Estudos Soroepidemiológicos , Argentina/epidemiologiaRESUMO
It is accepted that the practice of odontology implies a risk of BBV and HCV transmission but the study of does not. This work tries to determine the prevalence of HBv Ac and HCV Ac (by ELISA) in odontology students and whether there is any relation to the year of study and/or the presence of other risk factors. 188 students in their last three years of studies were investigated, all the participants filled out a clinical epidemiological form. 89 women (47.3%) and 99 men (52.7%), x age was 24.8. 50 (26.7%) had other risk factors. 160 (85.1%) fulfilled biosecurity norms and 40 (21.2%) had a labour accident. RESULTS: None of the analyzed sera were positive for HCV Ac (0%) and 1 was positive for HbcAc. CONCLUSION: The prevalence of HBv Ac and HCV Ac is extremely low with no relation to the year of study or any other risk factors
Assuntos
Humanos , Masculino , Feminino , Hepatite B , Hepatite C , Estudantes de Odontologia , Argentina , Ensaio de Imunoadsorção Enzimática , Hepatite B , Anticorpos Anti-Hepatite B , Hepatite C , Anticorpos Anti-Hepatite C , Transmissão de Doença Infecciosa do Paciente para o Profissional , Prevalência , Fatores de Risco , Estudos SoroepidemiológicosRESUMO
It is accepted that the practice of odontology implies a risk of BBV and HCV transmission but the study of does not. This work tries to determine the prevalence of HBv Ac and HCV Ac (by ELISA) in odontology students and whether there is any relation to the year of study and/or the presence of other risk factors. 188 students in their last three years of studies were investigated, all the participants filled out a clinical epidemiological form. 89 women (47.3
) and 99 men (52.7
), x age was 24.8. 50 (26.7
) had other risk factors. 160 (85.1
) fulfilled biosecurity norms and 40 (21.2
) had a labour accident. RESULTS: None of the analyzed sera were positive for HCV Ac (0
) and 1 was positive for HbcAc. CONCLUSION: The prevalence of HBv Ac and HCV Ac is extremely low with no relation to the year of study or any other risk factors.