1.
Org Biomol Chem
; 15(23): 5062-5069, 2017 Jun 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28567460
RESUMO
The nickel-catalyzed cyclization of in situ generated ortho-chlorobenzophenone hydrazone derivatives, to afford 3-(hetero)aryl-1H-indazoles, is documented for the first time. The product 1H-indazoles can be transformed subsequently in a one-pot procedure into 1,3-di(hetero)aryl-1H-indazoles via copper-catalyzed N-arylation with (hetero)aryl bromides.