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1.
Sci Rep ; 14(1): 14271, 2024 06 20.
Artigo em Inglês | MEDLINE | ID: mdl-38902321

RESUMO

Understanding the neural, metabolic, and psychological mechanisms underlying human altruism and decision-making is a complex and important topic both for science and society. Here, we investigated whether transcranial Direct Current Stimulation (tDCS) applied to two prefrontal cortex regions, the ventromedial prefrontal cortex (vmPFC, anode) and the right dorsolateral prefrontal cortex (DLPFC, cathode) can induce changes in self-reported emotions and to modulate local metabolite concentrations. We employed in vivo quantitative MR Spectroscopy in healthy adult participants and quantified changes in GABA and Glx (glutamate + glutamine) before and after five sessions of tDCS delivered at 2 mA for 20 min (active group) and 1 min (sham group) while participants were engaged in a charitable donation task. In the active group, we observed increased levels of GABA in vmPFC. Glx levels decreased in both prefrontal regions and self-reported happiness increased significantly over time in the active group. Self-reported guiltiness in both active and sham groups tended to decrease. The results indicate that self-reported happiness can be modulated, possibly due to changes in Glx concentrations following repeated stimulation. Therefore, local changes may induce remote changes in the reward network through interactions with other metabolites, previously thought to be unreachable with noninvasive stimulation techniques.


Assuntos
Emoções , Córtex Pré-Frontal , Estimulação Transcraniana por Corrente Contínua , Ácido gama-Aminobutírico , Humanos , Masculino , Feminino , Córtex Pré-Frontal/metabolismo , Córtex Pré-Frontal/fisiologia , Adulto , Emoções/fisiologia , Adulto Jovem , Ácido gama-Aminobutírico/metabolismo , Ácido Glutâmico/metabolismo , Altruísmo , Glutamina/metabolismo , Espectroscopia de Ressonância Magnética/métodos , Córtex Pré-Frontal Dorsolateral/metabolismo , Córtex Pré-Frontal Dorsolateral/fisiologia
2.
Artigo em Inglês | MEDLINE | ID: mdl-38765540

RESUMO

Objective: To present a series of cases with our initial experience and short-term outcomes of a modified vaginal mucosal flap urethroplasty. Methods: Patients diagnosed with urethral stricture and operated by the same operative technique between January 2012 and January 2018 were followed for at least 6 months. Uroflowmetry and clinical outcomes were evaluated. Results: Nineteen patients were included with an average age of 56.4 years, mean preoperative Qmax of 5.3 ml/s, and PVR of 101.4 mL. After 6 months of the procedure, the mean Qmax improved to 14.7 mL/s (p<0.05), PVR decreased to 47.3 mL (p<0.05), and 84.2% of all patients reported improvement in clinical self-reported symptoms. There was an improvement in symptoms such as voiding effort in 84.2% of patients, weak stream (89.5%), and recurrent urinary tract infection (85.7%). The success rate (absence of symptoms and normal Qmax with no significant PVR) of the procedure was 84.2%. Conclusion: The described technique was considered effective for the treatment of female urethra stricture, with a high clinical success rate and an objective improvement of Qmax and decrease in PVR after 6 months of the procedure.


Assuntos
Uretra , Estreitamento Uretral , Humanos , Estreitamento Uretral/cirurgia , Feminino , Pessoa de Meia-Idade , Resultado do Tratamento , Uretra/cirurgia , Adulto , Idoso , Estudos Retrospectivos , Procedimentos Cirúrgicos Urológicos/métodos , Retalhos Cirúrgicos , Vagina/cirurgia
3.
J Relig Health ; 63(1): 410-444, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37507577

RESUMO

Throughout history, people have reported nonordinary experiences (NOEs) such as feelings of oneness with the universe and hearing voices. Although these experiences form the basis of several spiritual and religious traditions, experiencing NOEs may create stress and uncertainty among those who experience such events. To provide a more systematic overview of the research linking NOEs with mental health, we present a systematic review of studies focusing on NOEs, well-being and mental health indicators. In a search of ProQuest and PsycInfo, we identified 725 references, of which 157 reported empirical data and were included in our review. Overall, the studies reviewed suggest that the relationship between NOEs and mental health is complex, varying according to a series of psychological and social factors. In particular, they suggest that appraisal processes play a fundamental role in the mental health outcomes of these experiences. However, we also highlight important methodological challenges such as the conceptual overlap between NOEs and well-being or psychopathological constructs, the conflation between experiences and appraisal processes in the assessment procedure, and the need for clearer assessment of the duration, controllability, impact on daily functioning and general context of the experiences. We provide a qualitative summary of empirical evidence and main themes of research and make recommendations for future investigation.


Assuntos
Saúde Mental , Humanos , Pesquisa Qualitativa
4.
Rev. bras. ginecol. obstet ; Rev. bras. ginecol. obstet;46: x-xx, 2024. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1559569

RESUMO

Abstract Objective: To present a series of cases with our initial experience and short-term outcomes of a modified vaginal mucosal flap urethroplasty. Methods: Patients diagnosed with urethral stricture and operated by the same operative technique between January 2012 and January 2018 were followed for at least 6 months. Uroflowmetry and clinical outcomes were evaluated. Results: Nineteen patients were included with an average age of 56.4 years, mean preoperative Qmax of 5.3 ml/s, and PVR of 101.4 mL. After 6 months of the procedure, the mean Qmax improved to 14.7 mL/s (p<0.05), PVR decreased to 47.3 mL (p<0.05), and 84.2% of all patients reported improvement in clinical self-reported symptoms. There was an improvement in symptoms such as voiding effort in 84.2% of patients, weak stream (89.5%), and recurrent urinary tract infection (85.7%). The success rate (absence of symptoms and normal Qmax with no significant PVR) of the procedure was 84.2%. Conclusion: The described technique was considered effective for the treatment of female urethra stricture, with a high clinical success rate and an objective improvement of Qmax and decrease in PVR after 6 months of the procedure.


Assuntos
Feminino , Procedimentos Cirúrgicos Urológicos , Estreitamento Uretral , Bexiga Urinária , Obstrução do Colo da Bexiga Urinária
5.
Pers Individ Dif ; 182: 111079, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34538995

RESUMO

We examined the relationship between emotional stability as a more stable personality trait and COVID-related worries with basic human values in a Brazilian sample (N = 578) that is strongly affected by COVID-19. We tested whether emotional stability would moderate the effect of infection and economic worries on personal values. In line with predictions, we found that infection worries were more strongly related to Security values, especially among individuals with less emotional stability, whereas economic worries were more strongly correlated with Power values, in particular among individuals with less emotional stability. Findings for Achievement values suggested perceived behavioral control effects for individuals high in Emotional Stability. Our findings provide insights into possible longer-term psychological effects of the current pandemic. Emotional dynamics in connection with worries created by the pandemic could influence values of importance for societal functioning in the short to medium term.

6.
J Atten Disord ; 25(4): 502-507, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-30520670

RESUMO

Impulsivity has a strong genetic component and is considered an endophenotype in many psychiatric disorders. Impulsivity in adult ADHD has become a focus of interest more recently because of its suggested prominence in this age. Objective: This study aimed to access self-reported impulsivity levels in biological parents of ADHD offspring, according to their status: non-ADHD (controls), remitted, nonremitted. Method: Impulsivity levels of 155 parents of ADHD children were compared according to their status using the Barratt Impulsiveness Scale (BIS-11). Results: The ADHD group presented the highest levels of impulsivity compared with all other groups. The remitted ADHD and control groups showed no significant differences in impulsivity levels. Conclusion: Impulsivity tended to remit alongside ADHD symptoms in remitters and to persist in those presenting with the residual form of adult ADHD suggesting it should not be considered as an endophenotype. Only the attentional dimension was impaired, cautioning against Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) impulsivity proposed criteria.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade , Adulto , Atenção , Transtorno do Deficit de Atenção com Hiperatividade/genética , Criança , Manual Diagnóstico e Estatístico de Transtornos Mentais , Endofenótipos , Humanos , Comportamento Impulsivo
7.
Dement Neuropsychol ; 13(1): 89-96, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31073384

RESUMO

The Von Restorff (isolation) effect refers to a stimulus that is more likely to be remembered amongst other stimuli in memory tasks. It has been demonstrated with different age ranges and methodologies. OBJECTIVE: To investigate: a) the presence of the isolation effect in elders tested with the new Brazilian Portuguese version of the Rey Auditory Verbal Learning Task (RAVLT) in which a word with potential emotional weight (mother) was introduced; b) whether isolation effects persist in memory disorders of different degrees of severity (Mild Cognitive Impairment [MCI]; Alzheimer's Dementia [AD]). METHODS: The RAVLT was administered to 287 consecutive volunteers. Individuals underwent medical and neuropsychological evaluation and were further sub-grouped into normal controls (n=114), MCI (n=87) and AD (n=86) patients. One-way analysis of variance (ANOVA) and Chi-squared tests were performed. Post-hoc Tukey analysis was conducted to assess significance of group differences. RESULTS: There were significant group effects on the learning curve. A W-shape - instead of the classical U-shape - was found for the serial position curve in all groups. CONCLUSION: The new Brazilian version of the RAVLT exhibited the Von Restorff effect, where this phenomenon was evident not only in older adults but also patients with MCI and AD, providing further psychometric measures for inter-group analyses.


Efeito de von Restorff (efeito de isolamento) refere-se ao estímulo que é mais facilmente lembrado em relação a outros em tarefas de memória. Tal efeito foi demonstrado em diferentes faixas etárias com diferentes metodologias. OBJETIVO: Investigar: a) presença do efeito de isolamento numa população idosa avaliada com a nova versão brasileira do Teste de Aprendizagem Auditivo-Verbal de Rey (RAVLT), em que uma palavra com potencial carga emocional ('mãe') foi introduzida; b) se o efeito de isolamento persiste em distúrbios de memória de diferentes gravidades (Comprometimento Cognitivo Leve [MCI]; Demência de Alzheimer [AD]). MÉTODOS: RAVLT foi aplicado em 287 voluntários. Indivíduos participaram de avaliações médica e neuropsicológica e foram posteriormente agrupados em controles normais (n=114), MCI (n=87) e DA (n=86). Análises de variância e testes de Chi-quadrado foram realizados. Análises post-hoc foram conduzidas para avaliar diferenças de características entre os grupos. RESULTADOS: Observaram-se efeitos significativos de grupo na curva de aprendizagem. Todos os grupos apresentaram curva de posição serial em formato W - invés do clássico formato em U. CONCLUSÃO: A nova versão brasileira do RAVLT evidenciou um efeito de von Restorff. Tal fenômeno foi visto não apenas em idosos, mas também em pacientes com MCI e AD, fornecendo medidas psicométricas adicionais para análises de diferenças intergrupais.

8.
Dement. neuropsychol ; 13(1): 89-96, Jan.-Mar. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-989671

RESUMO

ABSTRACT. The Von Restorff (isolation) effect refers to a stimulus that is more likely to be remembered amongst other stimuli in memory tasks. It has been demonstrated with different age ranges and methodologies. Objective: To investigate: a) the presence of the isolation effect in elders tested with the new Brazilian Portuguese version of the Rey Auditory Verbal Learning Task (RAVLT) in which a word with potential emotional weight (mother) was introduced; b) whether isolation effects persist in memory disorders of different degrees of severity (Mild Cognitive Impairment [MCI]; Alzheimer's Dementia [AD]). Methods: The RAVLT was administered to 287 consecutive volunteers. Individuals underwent medical and neuropsychological evaluation and were further sub-grouped into normal controls (n=114), MCI (n=87) and AD (n=86) patients. One-way analysis of variance (ANOVA) and Chi-squared tests were performed. Post-hoc Tukey analysis was conducted to assess significance of group differences. Results: There were significant group effects on the learning curve. A W-shape - instead of the classical U-shape - was found for the serial position curve in all groups. Conclusion: The new Brazilian version of the RAVLT exhibited the Von Restorff effect, where this phenomenon was evident not only in older adults but also patients with MCI and AD, providing further psychometric measures for inter-group analyses.


RESUMO. Efeito de von Restorff (efeito de isolamento) refere-se ao estímulo que é mais facilmente lembrado em relação a outros em tarefas de memória. Tal efeito foi demonstrado em diferentes faixas etárias com diferentes metodologias. Objetivo: Investigar: a) presença do efeito de isolamento numa população idosa avaliada com a nova versão brasileira do Teste de Aprendizagem Auditivo-Verbal de Rey (RAVLT), em que uma palavra com potencial carga emocional ('mãe') foi introduzida; b) se o efeito de isolamento persiste em distúrbios de memória de diferentes gravidades (Comprometimento Cognitivo Leve [MCI]; Demência de Alzheimer [AD]). Métodos: RAVLT foi aplicado em 287 voluntários. Indivíduos participaram de avaliações médica e neuropsicológica e foram posteriormente agrupados em controles normais (n=114), MCI (n=87) e DA (n=86). Análises de variância e testes de Chi-quadrado foram realizados. Análises post-hoc foram conduzidas para avaliar diferenças de características entre os grupos. Resultados: Observaram-se efeitos significativos de grupo na curva de aprendizagem. Todos os grupos apresentaram curva de posição serial em formato W - invés do clássico formato em U. Conclusão: A nova versão brasileira do RAVLT evidenciou um efeito de von Restorff. Tal fenômeno foi visto não apenas em idosos, mas também em pacientes com MCI e AD, fornecendo medidas psicométricas adicionais para análises de diferenças intergrupais.


Assuntos
Humanos , Testes de Memória e Aprendizagem , Disfunção Cognitiva , Memória , Testes Neuropsicológicos
9.
Neurourol Urodyn ; 38(1): 278-284, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30350876

RESUMO

AIMS: To evaluate the accuracy of dynamic ultrasonography (DUS), as a feasible alternative diagnostic method to identify detrusor overactivity (DO) in patients with neurogenic bladder. METHODS: We performed concurrent analysis of 81 pairs of urodynamic study (UDS) and DUS, in 63 patients with myelomeningocele (MMC), from June 2014 to February 2017. The assessment focused on bladder behavior during the filling phase, DO evaluation, DO with leakage, compliance, and maximum cystometric capacity (MCC). RESULTS: Patient age ranged from 3 months to 34 years (median, 84 months); 47.6% were male. Overall, 9.5% of patients had chronic kidney disease, 20.6% had recurrent urinary tract infection, 19.05% had vesicoureteral reflux, and 69.8% had constipation. Anticholinergic therapy was used by 41.3% of patients. DO was observed in 45.67% of patients and DO with leakage in 42.6%. Mean bladder compliance was 10.39 mL/cmH2 O and normal MCC was 56.79%. DUS had 91.89% sensitivity in identifying DO, 88.64% specificity, 87.18% positive predictive value, 92.86% negative predictive value, and 90.12% accuracy, with a kappa coefficient of 0.8 (P < 0.001). CONCLUSION: MMC follow-up is essential because urinary parameters can change during patient growth. The standard examination is invasive and has related complications, making noninvasive evaluation a desirable alternative, like DUS. Our data suggest that DO and MCC can be evaluated using DUS in patients with MMC. UDS should be performed in patients with abnormal findings on ultrasound evaluation or those with worsening of urinary tract function.


Assuntos
Meningomielocele/diagnóstico por imagem , Bexiga Urinaria Neurogênica/diagnóstico por imagem , Bexiga Urinária Hiperativa/diagnóstico por imagem , Urodinâmica/fisiologia , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Masculino , Meningomielocele/fisiopatologia , Estudos Prospectivos , Sensibilidade e Especificidade , Ultrassonografia , Bexiga Urinaria Neurogênica/fisiopatologia , Bexiga Urinária Hiperativa/fisiopatologia
10.
Acta Cir Bras ; 33(3): 197-206, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29668777

RESUMO

PURPOSE: To evaluate whether their combination was more effective than either alone in decreasing renal damage due to ischemia/reperfusion (I/R) injury in rats. METHODS: Thirty-two Wistar rats were assigned to four groups. Following right nephrectomy, their left kidneys were subjected to warm ischemia (IR), cold ischemia (TH+IR), intraperitoneal injection of 10 mg/kg melatonin (MEL+IR), or injection of 10 mg/kg melatonin followed by cold ischemia (MEL+TH+IR). Eight randomly assigned right kidneys constituted the control group. After 240 min of reperfusion, left nephrectomy was performed for histopathological evaluation, lipid peroxidation, and measurement of antioxidant enzyme activity. Serum was collected to measure urea and creatinine concentrations. RESULTS: Histopathological damage induced by ischemia and reperfusion was more attenuated in the MEL+TH+IR group than in the MEL+IR and TH+IR groups (p<0.037). Superoxide dismutase activity was significantly higher (p<0.029) and creatinine (p<0.001) and urea (p<0.001) concentrations were significantly lower in the MEL+TH+IR group than in the MEL+IR and TH+IR groups. CONCLUSION: The combination of melatonin (MEL) and topical hypothermia (TH) better protects against renal I/R injury than does MEL or TH alone.


Assuntos
Hipotermia Induzida/métodos , Rim/irrigação sanguínea , Melatonina/uso terapêutico , Traumatismo por Reperfusão/prevenção & controle , Animais , Terapia Combinada , Modelos Animais de Doenças , Masculino , Malondialdeído/metabolismo , Estresse Oxidativo , Ratos , Ratos Wistar , Traumatismo por Reperfusão/patologia , Superóxido Dismutase/metabolismo
11.
Acta cir. bras. ; 33(3): 197-206, mar. 2018. ilus, graf
Artigo em Inglês | VETINDEX | ID: vti-19581

RESUMO

Purpose: To evaluate whether their combination was more effective than either alone in decreasing renal damage due to ischemia/reperfusion (I/R) injury in rats. Methods: Thirty-two Wistar rats were assigned to four groups. Following right nephrectomy, their left kidneys were subjected to warm ischemia (IR), cold ischemia (TH+IR), intraperitoneal injection of 10 mg/kg melatonin (MEL+IR), or injection of 10 mg/kg melatonin followed by cold ischemia (MEL+TH+IR). Eight randomly assigned right kidneys constituted the control group. After 240 min of reperfusion, left nephrectomy was performed for histopathological evaluation, lipid peroxidation, and measurement of antioxidant enzyme activity. Serum was collected to measure urea and creatinine concentrations. Results: Histopathological damage induced by ischemia and reperfusion was more attenuated in the MEL+TH+IR group than in the MEL+IR and TH+IR groups (p<0.037). Superoxide dismutase activity was significantly higher (p<0.029) and creatinine (p<0.001) and urea (p<0.001) concentrations were significantly lower in the MEL+TH+IR group than in the MEL+IR and TH+IR groups. Conclusion: The combination of melatonin (MEL) and topical hypothermia (TH) better protects against renal I/R injury than does MEL or TH alone.(AU)


Assuntos
Animais , Ratos , Hipotermia Induzida , Melatonina , Traumatismo por Reperfusão , Ratos Wistar , Nefropatias , Rim
12.
Acta cir. bras ; Acta cir. bras;33(3): 197-206, Mar. 2018. graf
Artigo em Inglês | LILACS | ID: biblio-886272

RESUMO

Abstract Purpose: To evaluate whether their combination was more effective than either alone in decreasing renal damage due to ischemia/reperfusion (I/R) injury in rats. Methods: Thirty-two Wistar rats were assigned to four groups. Following right nephrectomy, their left kidneys were subjected to warm ischemia (IR), cold ischemia (TH+IR), intraperitoneal injection of 10 mg/kg melatonin (MEL+IR), or injection of 10 mg/kg melatonin followed by cold ischemia (MEL+TH+IR). Eight randomly assigned right kidneys constituted the control group. After 240 min of reperfusion, left nephrectomy was performed for histopathological evaluation, lipid peroxidation, and measurement of antioxidant enzyme activity. Serum was collected to measure urea and creatinine concentrations. Results: Histopathological damage induced by ischemia and reperfusion was more attenuated in the MEL+TH+IR group than in the MEL+IR and TH+IR groups (p<0.037). Superoxide dismutase activity was significantly higher (p<0.029) and creatinine (p<0.001) and urea (p<0.001) concentrations were significantly lower in the MEL+TH+IR group than in the MEL+IR and TH+IR groups. Conclusion: The combination of melatonin (MEL) and topical hypothermia (TH) better protects against renal I/R injury than does MEL or TH alone.


Assuntos
Animais , Masculino , Ratos , Traumatismo por Reperfusão/prevenção & controle , Hipotermia Induzida/métodos , Rim/irrigação sanguínea , Melatonina/uso terapêutico , Superóxido Dismutase/metabolismo , Traumatismo por Reperfusão/patologia , Ratos Wistar , Terapia Combinada , Estresse Oxidativo , Modelos Animais de Doenças , Malondialdeído/metabolismo
13.
Br J Soc Psychol ; 57(2): 346-366, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29322509

RESUMO

A visceral feeling of oneness with a group - identity fusion - has proven to be a stronger predictor of pro-group behaviours than other measures of group bonding, such as group identification. However, the relationship between identity fusion, other group alignment measures and their different roles in predicting pro-group behaviour is still controversial. Here, we test whether identity fusion is related to, but different from, unidimensional and multidimensional measures of group identification. We also show that identity fusion explains further variance of the endorsement of pro-group behaviour than these alternative measures and examine the structural and discriminant properties of identity fusion and group identification measures in three different contexts: nationality, religion, and football fandom. Finally, we extend the fusion literature to a new culture: Brazil. To the best of our knowledge, this is the first research explicitly addressing a comparison between these two forms of group alignment, identity fusion and identification with a group, and their role in predicting pro-group behaviours.


Assuntos
Cultura , Emoções , Futebol Americano/psicologia , Religião e Psicologia , Identificação Social , Adolescente , Adulto , Brasil , Feminino , Humanos , Masculino , Adulto Jovem
14.
Sci Rep ; 7(1): 16122, 2017 11 23.
Artigo em Inglês | MEDLINE | ID: mdl-29170383

RESUMO

Humans have a strong need to belong to social groups and a natural inclination to benefit ingroup members. Although the psychological mechanisms behind human prosociality have extensively been studied, the specific neural systems bridging group belongingness and altruistic motivation remain to be identified. Here, we used soccer fandom as an ecological framing of group membership to investigate the neural mechanisms underlying ingroup altruistic behaviour in male fans using event-related functional magnetic resonance. We designed an effort measure based on handgrip strength to assess the motivation to earn money (i) for oneself, (ii) for anonymous ingroup fans, or (iii) for a neutral group of anonymous non-fans. While overlapping valuation signals in the medial orbitofrontal cortex (mOFC) were observed for the three conditions, the subgenual cingulate cortex (SCC) exhibited increased functional connectivity with the mOFC as well as stronger hemodynamic responses for ingroup versus outgroup decisions. These findings indicate a key role for the SCC, a region previously implicated in altruistic decisions and group affiliation, in dovetailing altruistic motivations with neural valuation systems in real-life ingroup behaviour.


Assuntos
Altruísmo , Motivação/fisiologia , Recompensa , Futebol , Adulto , Encéfalo/diagnóstico por imagem , Encéfalo/fisiologia , Empatia/fisiologia , Feminino , Força da Mão/fisiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Córtex Pré-Frontal/diagnóstico por imagem , Córtex Pré-Frontal/fisiologia , Comportamento Social , Curetagem Subgengival
15.
Int. braz. j. urol ; 43(2): 304-310, Mar.-Apr. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-840818

RESUMO

ABSTRACT Objectives To assess patient satisfaction and quality of life after urethroplasty using two different self-reported outcome measures and to compare it with objective clinical data. Materials and Methods We prospectively collected data from 35 consecutive patients who underwent urethroplasty from January 2013 to September 2014. Patient demographics, International Prostate Symptom Score (IPSS), quality of life score, urethral stricture surgery patient-reported outcome measure (USS-PROM), maximum flow rate (Qmax) and post-void residual urine were collected before, two and eight months after surgery. Failure occurred when any postoperative instrumentation was performed. General estimation equation was used to compare the results and linear regression analysis to correlate both questionnaires with objective data. Results Mean age was 61 years. Urethroplasties were equally divided between anastomotic and buccal mucosa grafts and 19 patients (59.3%) had a previous urethral procedure. Overall success rate was 87.5%. IPSS improved from a mean 19 at baseline to 5.32 at 8 months (p <0.001). The mean USS-PROM score also improved from 13.21 preoperatively to 3.36 after surgery (p <0.001) and 84.3% of patients were satisfied or very satisfied with surgical results. Mean Qmax increased from 4.64mL/s to 11mL/s (p <0.001). Strong negative correlation was found respectively between flow rate and USS-PROM (r=-0.531, p <0.001) and with IPSS (r=-0.512, p <0.001). Conclusions Significant improvements in urinary symptoms and in quality of life are expected after urethroplasty and they are correlated with objective measures.


Assuntos
Humanos , Masculino , Adulto , Idoso , Idoso de 80 Anos ou mais , Adulto Jovem , Qualidade de Vida , Uretra/cirurgia , Estreitamento Uretral/cirurgia , Satisfação do Paciente/estatística & dados numéricos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Autorrelato/normas , Período Pós-Operatório , Micção/fisiologia , Estudos Prospectivos , Seguimentos , Resultado do Tratamento , Análise Custo-Benefício , Medidas de Resultados Relatados pelo Paciente , Pessoa de Meia-Idade
16.
Int Braz J Urol ; 43(2): 304-310, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28128915

RESUMO

OBJECTIVES: To assess patient satisfaction and quality of life after urethroplasty using two different self-reported outcome measures and to compare it with objective clinical data. MATERIALS AND METHODS: We prospectively collected data from 35 consecutive patients who underwent urethroplasty from January 2013 to September 2014. Patient demographics, International Prostate Symptom Score (IPSS), quality of life score, urethral stricture surgery patient-reported outcome measure (USS-PROM), maximum flow rate (Qmax) and post-void residual urine were collected before, two and eight months after surgery. Failure occurred when any postoperative instrumentation was performed. General estimation equation was used to compare the results and linear regression analysis to correlate both questionnaires with objective data. RESULTS: Mean age was 61 years. Urethroplasties were equally divided between anastomotic and buccal mucosa grafts and 19 patients (59.3%) had a previous urethral procedure. Overall success rate was 87.5%. IPSS improved from a mean 19 at baseline to 5.32 at 8 months (p < 0.001). The mean USS-PROM score also improved from 13.21 preoperatively to 3.36 after surgery (p< 0.001) and 84.3% of patients were satisfied or very satisfied with surgical results. Mean Qmax increased from 4.64mL/s to 11mL/s (p< 0.001). Strong negative correlation was found respectively between flow rate and USS-PROM (r=-0.531, p< 0.001) and with IPSS (r=-0.512, p < 0.001). CONCLUSIONS: Significant improvements in urinary symptoms and in quality of life are expected after urethroplasty and they are correlated with objective measures.


Assuntos
Satisfação do Paciente/estatística & dados numéricos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Qualidade de Vida , Autorrelato/normas , Uretra/cirurgia , Estreitamento Uretral/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise Custo-Benefício , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Medidas de Resultados Relatados pelo Paciente , Período Pós-Operatório , Estudos Prospectivos , Resultado do Tratamento , Micção/fisiologia , Adulto Jovem
17.
Estud. psicol. (Natal) ; 18(2): 223-229, Apr.-June 2013.
Artigo em Português | LILACS | ID: lil-685449

RESUMO

O comportamento religioso por muito tempo foi objeto de estudo apenas das ciências humanas, havendo poucas tentativas sistemáticas de uma interpretação Darwiniana de seu surgimento e/ou manutenção nas populações humanas. No entanto, as ciências naturais, juntamente com pesquisadores das mais diversas áreas, estão se voltando para o estudo sistemático do comportamento religioso através de uma perspectiva evolucionista. Em função desse novo e crescente campo de pesquisa, iremos apresentar algumas das principais hipóteses evolucionistas para a manutenção do comportamento religioso nas populações humanas e analisar os principais resultados empíricos encontrados até o momento. Apesar da enorme riqueza de crenças e reconhecida relevância dada à religião no nosso país, pouquíssimos pesquisadores brasileiros trabalham com esse tema. Acreditamos que essa revisão poderá ser importante para a divulgação e incentivo ao estudo do comportamento religioso pela perspectiva evolucionista no nosso país por pesquisadores das mais diversas áreas...


Religious behavior has long been the object of study by the humanities, with only few attempts to analyze its emergence and maintenance in human population from a Darwinian perspective. However, the natural sciences, together with researchers from various fields, are turning to the systematic study of religious behavior through an evolutionary perspective. Due to this new and growing field of research, we will review some of the major evolutionary hypotheses for the maintenance of religious behavior in human populations and analyze the main empirical results obtained until now. Despite the diversity of beliefs and recognized importance given to religion in our country, very few Brazilian researchers are working on this theme. We believe that this review may be important to raise awareness and encourage the study of religious behavior by evolutionary perspective on our country by scholars from different fields...


El comportamiento religioso ha sido durante mucho tiempo objeto de estudio sólo de las humanidades, y considerado el resultado de las influencias culturales y sin influencia biológica. Sin embargo, las ciencias naturales, junto con investigadores de diversos campos, están recurriendo al estudio sistemático de la conducta religiosa a través de una perspectiva evolutiva. Debido a este nuevo y creciente campo de la investigación, vamos a presentar algunas de las principales hipótesis evolutivas para el mantenimiento de la conducta religiosa en las poblaciones humanas y analizar los principales resultados empíricos obtenidos hasta ahora. A pesar de la gran cantidad de creencias y reconocida importancia dada a la religión en nuestro país, muy pocos investigadores brasileños trabajan en este tema. Creemos que este examen puede ser importante para difundir y fomentar el estudio de la conducta religiosa por la perspectiva evolutiva en nuestro país por investigadores de diversos campos...


Assuntos
Humanos , Evolução Biológica , Religião e Ciência , Seleção Genética
18.
Estud. psicol. (Natal) ; 18(2): 223-229, abr.-jun. 2013.
Artigo em Português | Index Psicologia - Periódicos | ID: psi-59357

RESUMO

O comportamento religioso por muito tempo foi objeto de estudo apenas das ciências humanas, havendo poucas tentativas sistemáticas de uma interpretação Darwiniana de seu surgimento e/ou manutenção nas populações humanas. No entanto, as ciências naturais, juntamente com pesquisadores das mais diversas áreas, estão se voltando para o estudo sistemático do comportamento religioso através de uma perspectiva evolucionista. Em função desse novo e crescente campo de pesquisa, iremos apresentar algumas das principais hipóteses evolucionistas para a manutenção do comportamento religioso nas populações humanas e analisar os principais resultados empíricos encontrados até o momento. Apesar da enorme riqueza de crenças e reconhecida relevância dada à religião no nosso país, pouquíssimos pesquisadores brasileiros trabalham com esse tema. Acreditamos que essa revisão poderá ser importante para a divulgação e incentivo ao estudo do comportamento religioso pela perspectiva evolucionista no nosso país por pesquisadores das mais diversas áreas.(AU)


Religious behavior has long been the object of study by the humanities, with only few attempts to analyze its emergence and maintenance in human population from a Darwinian perspective. However, the natural sciences, together with researchers from various fields, are turning to the systematic study of religious behavior through an evolutionary perspective. Due to this new and growing field of research, we will review some of the major evolutionary hypotheses for the maintenance of religious behavior in human populations and analyze the main empirical results obtained until now. Despite the diversity of beliefs and recognized importance given to religion in our country, very few Brazilian researchers are working on this theme. We believe that this review may be important to raise awareness and encourage the study of religious behavior by evolutionary perspective on our country by scholars from different fields.(AU)


El comportamiento religioso ha sido durante mucho tiempo objeto de estudio sólo de las humanidades, y considerado el resultado de las influencias culturales y sin influencia biológica. Sin embargo, las ciencias naturales, junto con investigadores de diversos campos, están recurriendo al estudio sistemático de la conducta religiosa a través de una perspectiva evolutiva. Debido a este nuevo y creciente campo de la investigación, vamos a presentar algunas de las principales hipótesis evolutivas para el mantenimiento de la conducta religiosa en las poblaciones humanas y analizar los principales resultados empíricos obtenidos hasta ahora. A pesar de la gran cantidad de creencias y reconocida importancia dada a la religión en nuestro país, muy pocos investigadores brasileños trabajan en este tema. Creemos que este examen puede ser importante para difundir y fomentar el estudio de la conducta religiosa por la perspectiva evolutiva en nuestro país por investigadores de diversos campos.(AU)


Assuntos
Evolução Biológica , Religião e Ciência , Seleção Genética
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