RESUMO
An epidemic that occurred at the Hospital Infantil de México is reported. Salmonella poona (roup G) was isolated in 154 patients: 122 in stool cultures, 23 in blood cultures and 9 in meningitis; out of the latter, 6 were newborns under 2 months of age. The strain showed resistance to several antibiotics: ampicillin, chloramphenicol, gentamicin, kanamycin, tetracycline, carbenicillin, cephalosporine, streptomycin and sulfonamides. Seventy per cent of the strains were resistant to 500 mcg/ml (highest concentration used) and 65% to the same dose of chloramphenicol.
Assuntos
Antibacterianos/farmacologia , Resistência às Penicilinas , Infecções por Salmonella/epidemiologia , Salmonella/efeitos dos fármacos , Ampicilina/uso terapêutico , Criança , Cloranfenicol/uso terapêutico , Surtos de Doenças , Avaliação de Medicamentos , Humanos , Lactente , Recém-Nascido , México , Testes de Sensibilidade Microbiana , Salmonella/classificação , Salmonella/isolamento & purificação , Infecções por Salmonella/tratamento farmacológicoRESUMO
The authors report two newborn infants, one with sepsis and the other one with meningitis, discussing clinical and epidemiological aspects of this infection.
Assuntos
Doenças do Recém-Nascido/microbiologia , Listeria monocytogenes/isolamento & purificação , Meningite por Listeria/microbiologia , Sepse/microbiologia , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Doenças do Prematuro/microbiologiaRESUMO
Staphylococcus aureus is a bacterium which has shown variations, as to susceptibility, to antimicrobial agents. By the plate dilution method, response to 12 different antibiotics is studied in 609 strains isolated from children admitted, or who attended the outpatient clinic of the Hospital Infantil de México, between 1973 and 1974. Ninety per cent or over, of all strains, were sensitive to eight of the antibiotics. The most effective were: gentamicin, (99.8%), cephalothin and cloxacillin (99%). Lesser sensitivity was found to penicillin (28.7%), ampicillin (33.5%) and tetracycline (49%). In general, resistance was greater in cases of surgical wounds and abscesses, and lesser in respiratory infections (pharyngeal exudates and bronchoaspirations). All strains isolated from purulent ophthalmias showed resistance to penicillin and 91%, to ampicillin.