1.
J Pediatr
; 121(4): 650-1, 1992 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1403405
RESUMO
A 16-year-old boy with short stature and mild primary hypothyroidism received subcutaneous injections of either recombinant human growth hormone or placebo in diluent that contained glycerol and m-cresol as a preservative. While he was receiving the study drug, myalgia developed and serum creatine kinase values were elevated. Both resolved when injections were stopped and recurred when injections of diluent alone were given. The myalgia and elevated creatine kinase activity were apparently caused by a component of the diluent.
Assuntos
Creatina Quinase/sangue , Cresóis/efeitos adversos , Doenças Musculares/induzido quimicamente , Dor/induzido quimicamente , Conservantes Farmacêuticos/efeitos adversos , Adolescente , Hormônio do Crescimento/administração & dosagem , Humanos , Injeções Subcutâneas , Masculino , Doenças Musculares/enzimologia , Dor/enzimologia
2.
J Pediatr
; 105(4): 666-8, 1984 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6481548
3.
J Pediatr
; 94(5): 841-3, 1979 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-448504
4.
J Pediatr
; 93(4): 619-21, 1978 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-702239
5.
J Pediatr
; 83(2): 345, 1973 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4717593