RESUMO
RESUMEN La dermatitis actínica crónica (DAC) - dermatitis por fotosensibilidad, reacción solar persistente o su variante extrema el reticuloide actínico- es una fotodermatosis crónica, propia del adulto más frecuente en el sexo masculino provocada por rayos ultravioletas (UVB), (UVA) y luz visible. El diagnóstico es clínico, caracterizado por placas eccematosas y liquenificadas pruriginosas en aéreas expuestas al sol. Se cree que el DAC se debe a la fotosensibilización secundaria de un antígeno endógeno de la piel.
ABSTRACT Chronic actinic dermatitis (ACD) - photosensitivity dermatitis, persistent solar reaction or its extreme variant actinic reticuloid - is a chronic photodermatosis, typical of the adult male caused by ultraviolet (UVB), (UVA) and visible light. The diagnosis suggested by clinical researchers, characterized by eczematous and lichenified pruritic plaques in areas exposed to the sun. It is believed that DAC is due to the secondary photosensitization of an endogenous skin antigen.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Transtornos de Fotossensibilidade/diagnóstico , Transtornos de Fotossensibilidade/terapia , Dermatite/fisiopatologia , Diagnóstico DiferencialRESUMO
Motivados por la falta de datos estadísticos de cáncer de piel en nuestra provincia, realizamos un estudio retrospectivo en 3325 biopsias realizadas en nuestro servicio entre los años 1982 y 1999; encontrando un total de 326 casos de piel, de los cuales 222 corresponden a epitolioma basocelular, 71 a epitelioma espinocelular y 33 melanoma maligno
Assuntos
Humanos , Estudos Retrospectivos , Neoplasias Cutâneas , Neoplasias Cutâneas/classificaçãoRESUMO
Motivados por la falta de datos estadísticos de cáncer de piel en nuestra provincia, realizamos un estudio retrospectivo en 3325 biopsias realizadas en nuestro servicio entre los años 1982 y 1999; encontrando un total de 326 casos de piel, de los cuales 222 corresponden a epitolioma basocelular, 71 a epitelioma espinocelular y 33 melanoma maligno(AU)
Assuntos
Humanos , Neoplasias Cutâneas/diagnóstico por imagem , Neoplasias Cutâneas/classificação , Estudos RetrospectivosRESUMO
The antinociceptive effects of morusin (1), the main prenylflavonoid present in the Morus nigra root barks have been investigated in classical models of pain in mice. The results showed that 1 exhibits a promising antinociceptive or analgesic profile by the intraperitoneal route, being more potent than some standard drugs used as reference. The mechanism by which the morusin exerts antinociceptive activity still remains undetermined, but our results strongly suggest that it involves the participation of the opioid system.
Assuntos
Analgésicos/farmacologia , Flavonoides/farmacologia , Plantas Medicinais/química , Analgésicos/isolamento & purificação , Animais , Relação Dose-Resposta a Droga , Feminino , Flavonoides/isolamento & purificação , Masculino , Camundongos , Raízes de Plantas/químicaRESUMO
Se efctua un estudio retrospectivo de la consulta estomatológica en el servicio de dermatología pediátrica desde mayo de 1997 a mayo de 1999. Mostramos la prevalencia de la patología, tipo de lesiones, su frecuencia y su relación con la edad y el sexo. Concluímos que las patologías más frecuentes fueron Mucocele y Enfermedad Mano-pie-boca, con un predominio en ambas del sexp femenino
Assuntos
Humanos , Pré-Escolar , Masculino , Feminino , Medicina Bucal , Prevalência , Encaminhamento e ConsultaRESUMO
Se efctua un estudio retrospectivo de la consulta estomatológica en el servicio de dermatología pediátrica desde mayo de 1997 a mayo de 1999. Mostramos la prevalencia de la patología, tipo de lesiones, su frecuencia y su relación con la edad y el sexo. Concluímos que las patologías más frecuentes fueron Mucocele y Enfermedad Mano-pie-boca, con un predominio en ambas del sexp femenino(AU)
Assuntos
Humanos , Pré-Escolar , Masculino , Feminino , Medicina Bucal , Prevalência , Encaminhamento e ConsultaRESUMO
Se presentan dos casos de melanoma acral de localización imterdigital en una mujer de 67 años y en un hombre de 65. Se realiza una reseña bibliográfica de 28 trabajos de la literatura médica, con 843 casos de esta enfermedad. Se aprecia de este modo que la mayor frecuencia es la plantar seguida por la ungueal, siendo la ubicada en los espacios de los dedos, la de menor cuantía
Assuntos
Humanos , Masculino , Feminino , Idoso , Doenças do Pé/diagnóstico , Doenças do Pé/cirurgia , Melanoma/classificaçãoRESUMO
Se presentan dos casos de melanoma acral de localización imterdigital en una mujer de 67 años y en un hombre de 65. Se realiza una reseña bibliográfica de 28 trabajos de la literatura médica, con 843 casos de esta enfermedad. Se aprecia de este modo que la mayor frecuencia es la plantar seguida por la ungueal, siendo la ubicada en los espacios de los dedos, la de menor cuantía(AU)
Assuntos
Humanos , Masculino , Feminino , Idoso , Melanoma/classificação , Doenças do Pé/diagnóstico , Doenças do Pé/cirurgiaRESUMO
The authors report the clinical and angiographical findings of two cases of familial hemifacial spasm. This is the fifth description in the literature and presents mother and daughter at the ages of 76 and 51 respectively, in whom the left side was affected. They underwent exams of angioresonance that showed dolichobasilar with left side origin in both patients. The exams also demonstrated postero-inferior cerebellar artery very developed and irregularities in the walls of the vertebral and basilar arteries suggestive of arteriosclerosis in the mother and slightly elongated intracranial vessels in the daughter. Literature review and etiology data of the hemifacial spasm are focused.
Assuntos
Espasmo Hemifacial/genética , Idoso , Toxinas Botulínicas Tipo A/uso terapêutico , Feminino , Espasmo Hemifacial/diagnóstico , Espasmo Hemifacial/tratamento farmacológico , Humanos , Angiografia por Ressonância Magnética , Pessoa de Meia-Idade , Fármacos Neuromusculares/uso terapêuticoRESUMO
Using scintigraphy, we have studied the lacrimal drainage from the conjunctival sac of normal subjects and patients who have undergone dacryocystorhinostomy. A mathematical model of drainage was constructed that accurately described the complete activity curves for both groups. The initial rate of drainage was shown to be a relevant parameter to characterize drainage, and it was found to be different from normals to patients, indicating that the lacrimal pump mechanism is affected by dacryocystorhinostomy.
Assuntos
Dacriocistorinostomia , Doenças do Aparelho Lacrimal/fisiopatologia , Aparelho Lacrimal/fisiopatologia , Lágrimas/fisiologia , Adolescente , Adulto , Idoso , Análise de Variância , Humanos , Aparelho Lacrimal/diagnóstico por imagem , Doenças do Aparelho Lacrimal/cirurgia , Pessoa de Meia-Idade , Modelos Teóricos , Cintilografia , Tecnécio , Resultado do TratamentoRESUMO
The case of 22-year old, white woman with bilateral orbital myositis following an acute upper respiratory tract infection is reported. The most important clinical findings were ocular pain, proptosis, restricted eye motility and swelling of the eyelids. The enlarged eye muscles were seen on orbital computerized tomography scan. The clinical findings of inflammatory orbital myositis and clinical response to corticotherapy are emphasized.
Assuntos
Pseudotumor Orbitário , Doença Aguda , Adulto , Feminino , Glucocorticoides/uso terapêutico , Humanos , Pseudotumor Orbitário/diagnóstico por imagem , Pseudotumor Orbitário/tratamento farmacológico , Pseudotumor Orbitário/virologia , Prednisona/uso terapêutico , Infecções Respiratórias/complicações , Tomografia Computadorizada por Raios XRESUMO
Blepharospasm is form of focal dystonia characterized by involuntary and repetitive contractions involving the orbicular oculi muscle. Fourteen patients with blepharospasm were submitted to botulinum toxin type A injections. Of these 14 cases, 6 were male and 8 female. The mean age was 58 years (range: 33 to 76 years) with illness duration ranging from 1 to 25 years (average: 7.3 years). All patients have been treated with conventional therapies with poor results, but presented a good response to botulinum toxin type A. The average latent period was 3 days (range: 0 to 10); maximum effect of treatment was observed after 16 days. The mean duration of maximum response was 90 days. The main side effects of botulinum toxin injections were ptosis and lagophtalmos.
Assuntos
Antidiscinéticos/uso terapêutico , Blefarospasmo/tratamento farmacológico , Toxinas Botulínicas/uso terapêutico , Adulto , Idoso , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Tempo de ReaçãoRESUMO
Nine patients with "idiopathic" hemifacial spasm were evaluated with cranial magnetic resonance imaging and angiography. Alterations of the posterior fossa vasculature, possibly related to the facial nerve irritation, were found in 8 patients (88%). Magnetic resonance angiography is a noninvasive procedure and appears to be a sensitive method to evaluate the hemifacial spasm etiology.
Assuntos
Músculos Faciais/patologia , Doenças do Nervo Facial/diagnóstico , Angiografia por Ressonância Magnética , Espasmo/diagnóstico , Adulto , Idoso , Músculos Faciais/fisiopatologia , Doenças do Nervo Facial/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Contração Muscular , Sensibilidade e Especificidade , Espasmo/etiologiaRESUMO
We report the case of a 56-years-old woman patient, born to unrelated parents, who since 26-years-old gradually developed bradykinesia, rigidity, tremor of both hands, and speech and gait difficulties. Her past history was unremarkable. There was no family history of neurologic disease. She was admitted to our Hospital at age 39 and at that time she presented a full parkinsonian syndrome. The following tests were normal or negative: routine blood studies, serum copper, ceruloplasmin and cerebrospinal fluid examination. There was not Kayser-Fleicher ring, and fundoscopic examination revealed no abnormalities. Levodopa was introduced and response was good for more than ten years, despite early-onset of dyskinesias (three months after the introduction of the drug). After 30 years under levodopa she still presents a moderate response but with severe fluctuations of the motor performance. Except for slowness of cognition she developed no other neuropsychological impairments, and a recent neurological examination disclosed no abnormalities besides a parkinsonian syndrome. One year ago, a magnetic resonance imaging (MRI) was performed and showed bilateral, symmetrical lesions with "eye-of-the-tiger" pattern. This case illustrates the pathological heterogeneity of early-onset parkinsonism and suggests the possibility to find the typical MRI lesions seen in Hallervorden-Spatz disease in other degenerative affections involving globus pallidus.