RESUMO
The aim of this article is to introduce the museum we have at the Pathology Department, School of Medicine of the National University of Rosario, Argentina. The origin dates from to 1922 when Dermatology Professor Dr. Enrique P. Fidanza bought moulages at L'Hôpital Saint-Louis in Paris for the purpose of teaching. The collection included around 100 moulages and was worth approximately 1000 dollars. These pieces were exhibited at the Dermatology Department for many years and later moved to the Pathology Department where some pieces started being repaired, whereas others have deteriorated. The collection is composed of 100 moulages done by a French craftsman by the name of Niclet and 258 made by Argentine craftsmen including Alba Ramirez and G. Rouzaut, among others. The pieces are classified according to different dermatological diseases such as: the different stages of syphilis, lupus, benign and malignant neoplasm, infectious diseases, etc.
Assuntos
Dermatologia/história , Medicina nas Artes/história , Modelos Anatômicos , Dermatopatias/história , História do Século XIX , História do Século XX , Humanos , MuseusRESUMO
La docimasia pulmonar es una prueba muy útil en la actividad médica forense para investigar y diagnosticar la existencia de vida extrauterina del recién nacido, para establecer si el feto nació muerto o sufrió el delito de homicidio. Una cita repetida en algunos textos de Medicina Legal, de la cual no se menciona en ningún caso la fuente, mostró varias curiosidades al intentar verificarla. Las obras sobre Historia de la Medicina consultadas no lograron despejar las dudas sobre la veracidad del dato y tampoco agotan los temas tratados. Este sería el caso de Galeno, cuya obra y personalidad tanta influencia tuvieron durante mil quinientos años de nuestra era y aún continúan generando controversias. No se halló ningún dato concreto sobre el conocimiento atribuido a Galeno de la docimasia pulmonar hidrostática, aunque tampoco se encontraron datos que rechacen categóricamente el aserto. Paradójicamente, las referencias históricas relacionadas con la mencionada docimasia en los textos de Medicina Legal no mencionan al holandés Jan Swammerdam, quien habría sido el que la describió y fundamentó (AU)
Hydrostatic pulmonary docimasy is a very useful test in forensic medical activity to investigate and diagnose the existence of extra-uterine life of the newborn, to determine whether the fetus was stillborn or was murdered. A repeated reference in some texts of Forensic Medicine, without mention of the source, showed several paradoxes when we tried to verify it. Books on the History of Medicine consulted failed to dispel doubts about the veracity of the data and did not go to the bottom of the issue. This is the case of Galen, whose work and personality had much influence during 1,500 years of our era and continues to generate controversy. No firm information was found about the knowledge Galen might have had on hydrostatic pulmonary docimasy; but no source categorically rejected the possibility. Paradoxically, the historical references on docimasy mentioned in the texts of Forensic Medicine fail to mention name of the Dutch Jan Swammerdam, who described and explained the method (AU).
Assuntos
Humanos , Recém-Nascido , História do Século XVII , Medicina Legal/história , Medicina Legal/métodos , História da Medicina , Recém-NascidoRESUMO
La docimasia pulmonar es una prueba muy útil en la actividad médica forense para investigar y diagnosticar la existencia de vida extrauterina del recién nacido, para establecer si el feto nació muerto o sufrió el delito de homicidio. Una cita repetida en algunos textos de Medicina Legal, de la cual no se menciona en ningún caso la fuente, mostró varias curiosidades al intentar verificarla. Las obras sobre Historia de la Medicina consultadas no lograron despejar las dudas sobre la veracidad del dato y tampoco agotan los temas tratados. Éste sería el caso de Galeno, cuya obra y personalidad tanta influencia tuvieron durante mil quinientos años de nuestra era y aún continúan generando controversias. No se halló ningún dato concreto sobre el conocimiento atribuido a Galeno de la docimasia pulmonar hidrostática, aunque tampoco se encontraron datos que rechacen categóricamente el aserto. Paradójicamente, las referencias históricas relacionadas con la mencionada docimasia en los textos de Medicina Legal no mencionan al holandés Jan Swammerdam, quien habría sido el que la describió y fundamentó
Hydrostatic pulmonary docimasy is a very useful test in forensic medical activity to investigate and diagnose the existence of extra-uterine life of the newborn, to determine whether the fetus was stillborn or was murdered. A repeated reference in some texts of Forensic Medicine, without mention of the source, showed several paradoxes when we tried to verify it. Books on the History of Medicine consulted failed to dispel doubts about the veracity of the data and did not go to the bottom of the issue. This is the case of Galen, whose work and personality had much influence during 1,500 years of our era and continues to generate controversy. No firm information was found about the knowledge Galen might have had on hydrostatic pulmonary docimasy; but no source categorically rejected the possibility. Paradoxically, the historical references on docimasy mentioned in the texts of Forensic Medicine fail to mention name of the Dutch Jan Swammerdam, who described and explained the method .
Assuntos
Humanos , Recém-Nascido , História do Século XVII , Medicina Legal/história , Medicina Legal/métodos , História da Medicina , Recém-NascidoRESUMO
Endosulfan can induce convulsions that could lead to brain damage. The variability and lack of specificity of neurological signs and symptoms in the pre-convulsive stages makes early diagnosis difficult. We sought to determine if electrophysiological exploration of the cerebral cortex could yield objective signs of endosulfan intoxication at levels that do not elicit convulsions. Endosulfan was administered intravenously to Sprague-Dawley adult rats under urethane anesthesia at doses from 0.5 to 4mg/kg. EEG power and the evoked potentials (EP) to forepaw electrical stimulation were studied over the contralateral (S1CL) and homolateral (S1HL) cortical somatosensory areas and the contralateral visual area (V1CL). At each area, five EP waves were measured. Arterial blood pressure, heart rate and body temperature were also recorded. Endosulfan induced a dose-related increase in EPs at all sites. At S1CL, EP peak amplitude was greater than baseline at 1, 2 and 4mg/kg for the first negative, second positive and third negative waves, and at 2 and 4mg/kg for the first and third positive waves. Similar but less marked trends were observed at S1HL and V1CL. A shift of EEG power to higher frequencies (alpha and beta EEG bands) was only present at 4mg/kg. In conclusion, endosulfan induced a large increase of cortical evoked potentials amplitudes at doses that did not elicit convulsions. These responses could be used as a non-invasive diagnostic tool to detect low-level endosulfan intoxication in humans and to help establish the NOAEL and LOAEL levels of this pollutant.