RESUMO
BACKGROUND: Hepatic circulatory disturbances have been associated with obesity and fatty liver in humans. In the veterinary literature, however, there is limited information regarding the effects of different body condition scores (BCS) on liver hemodynamic indices in dogs. OBJECTIVES: To investigate the influence of BCS on liver hemodynamic indices. ANIMALS: Fifty-three client-owned dogs of various breeds were included. METHODS: Prospective observational study. Dogs were divided into 3 BCS groups using a 5-point scale: G1 - 12 ideal dogs, G2 - 21 overweight dogs, G3 - 20 obese dogs. Mean portal velocity (MPV), portal blood flow volume (PBFV), portal congestion index (PCI), hepatic artery resistivity index (HARI), and hepatic vein (HV) spectral wave were obtained by pulsed Doppler sonography. Alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), and alanine aminotransferase (ALT) activities were determined. Liver enzymes activities and liver hemodynamic indices were compared among groups. RESULTS: Obese dogs had lower MPV, higher percentage of abnormal hepatic vein spectral wave and higher median ALP activity than did ideal dogs (P < 0.05). Overweight and obese dogs had lower PBFV than ideal dogs (P < 0.01). Overweight dogs had higher median GGT activity than ideal dogs (P < 0.05). No difference was observed for PCI, HARI and median ALT activity among the groups. CONCLUSIONS AND CLINICAL IMPORTANCE: Obesity was associated with changes in portal vein indices and in HV spectral wave. These changes were accompanied by significant differences in some liver enzymes activities and could be a sign of early liver disease.
Assuntos
Doenças do Cão/fisiopatologia , Fígado/irrigação sanguínea , Obesidade/veterinária , Sobrepeso/veterinária , Animais , Doenças do Cão/diagnóstico por imagem , Cães , Feminino , Hemodinâmica/fisiologia , Fígado/diagnóstico por imagem , Circulação Hepática/fisiologia , Masculino , Obesidade/diagnóstico por imagem , Obesidade/fisiopatologia , Sobrepeso/diagnóstico por imagem , Sobrepeso/fisiopatologia , Ultrassonografia Doppler/veterináriaRESUMO
O Schistosomus reflexus (SR) é uma anomalia congênita fatal e rara, primariamente observada em ruminantes, a qual apresenta feto com dorsoflexão da coluna vertebral, exposição das vísceras abdominais e torácicas e escoliose. Foi realizada uma cesariana de ovelha da raça Dorper, em propriedade da região de Botucatu-SP. Pelas características gerais e achados de necropsia, tratava-se de um caso de SR. A radiografia revelou acentuado desvio ventrodorsal do segmento da coluna vertebral toracolombar e deformidades das costelas. Na tomografia computadorizada, observou-se presença da integridade dos ossos e órgãos, exceto ausência de uma vértebra lombar. Não havia dados na literatura de diagnóstico por imagem de SR em ovinos, portanto procedeu-se, de forma inédita, a exames radiográfico e tomográfico do feto.
Schistosomus reflexus (SR) is a rare and fatal congenital anomaly, primarily observed in ruminants, presenting fetus with dorsiflexion of the vertebral column, exposure of thoracic and visceral organs, and scoliosis. A caesarian was performed on a Dorper sheep on a farm in Botucatu-SP and according to the general characteristics and findings observed in the necropsy of the fetus it was an SR case. The radiography indicated a marked ventro-dorsal deviation of the thoracolumbar column segment and deformity of the ribs. On the computed tomography the integrity of the bones and organs were detected, except for the absence of a lumbar vertebra. No data were available in the literature for SR diagnosis in sheep by image, so radiographic and tomographic exams of the fetus were done.
Assuntos
Animais , Patologia , Schistosoma , Ruminantes , RadiografiaRESUMO
O Schistosomus reflexus (SR) é uma anomalia congênita fatal e rara, primariamente observada em ruminantes, a qual apresenta feto com dorsoflexão da coluna vertebral, exposição das vísceras abdominais e torácicas e escoliose. Foi realizada uma cesariana de ovelha da raça Dorper, em propriedade da região de Botucatu-SP. Pelas características gerais e achados de necropsia, tratava-se de um caso de SR. A radiografia revelou acentuado desvio ventrodorsal do segmento da coluna vertebral toracolombar e deformidades das costelas. Na tomografia computadorizada, observou-se presença da integridade dos ossos e órgãos, exceto ausência de uma vértebra lombar. Não havia dados na literatura de diagnóstico por imagem de SR em ovinos, portanto procedeu-se, de forma inédita, a exames radiográfico e tomográfico do feto.(AU)
Schistosomus reflexus (SR) is a rare and fatal congenital anomaly, primarily observed in ruminants, presenting fetus with dorsiflexion of the vertebral column, exposure of thoracic and visceral organs, and scoliosis. A caesarian was performed on a Dorper sheep on a farm in Botucatu-SP and according to the general characteristics and findings observed in the necropsy of the fetus it was an SR case. The radiography indicated a marked ventro-dorsal deviation of the thoracolumbar column segment and deformity of the ribs. On the computed tomography the integrity of the bones and organs were detected, except for the absence of a lumbar vertebra. No data were available in the literature for SR diagnosis in sheep by image, so radiographic and tomographic exams of the fetus were done.(AU)