RESUMO

Crude extracts of Agave americana contain two utero-active compounds. One of these, tentatively named "Fraction B", has been purified to chromatographic homogeneity. Its pharmacological actions are similar to those of acetylcholine. However its chromatographic and electrophoretic mobilities are different. Some chemical properties of fraction B are compatible with the structure of an acyl derivative of choline different from acetylcholine

Assuntos

Ratos , Animais , Feminino , Extratos Vegetais/farmacologia , Útero , Cromatografia em Camada Fina , Extratos Vegetais/isolamento & purificação , Ratos Endogâmicos

Assuntos

Ratos , Animais , Feminino , Ácidos Nicotínicos/farmacologia , Etanol/antagonistas & inibidores , Piridoxina/farmacologia , Cloretos/metabolismo , Combinação de Medicamentos , Ácido gama-Aminobutírico/metabolismo , Ratos Endogâmicos , Receptores de GABA-A/efeitos dos fármacos , Receptores de GABA-A/metabolismo , Sono , Transporte Biológico