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Arch Physiol Biochem ; 115(1): 28-33, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19267280

RESUMO

AIM: To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians. METHODS: It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels, lipid profiles and glucose were measured in fasting blood samples. RESULTS: Adiponectin levels were significantly lower (P = 0.003) in diabetics (n = 60) than non diabetics (n = 73). No correlation between adiponectin and inflammatory markers was found. Adiponectin levels were negatively correlated with BMI adjusting for age and diabetic status, and gender (beta = -0.200, P = 0.020; beta = -0.235, P = 0.004). CONCLUSIONS: No correlation exists between adiponectin and inflammatory markers. Adiponectin levels are lower in type 2 diabetic Trinidadians than in non-diabetics and decreases with increasing adiposity, using BMI as the marker.


Assuntos
Adiponectina/sangue , Biomarcadores/sangue , Diabetes Mellitus Tipo 2/sangue , Inflamação/sangue , Obesidade/sangue , Adolescente , Adulto , Idoso , Antropometria , Proteína C-Reativa/metabolismo , Estudos Transversais , Feminino , Humanos , Interleucina-6/sangue , Masculino , Pessoa de Meia-Idade , Trinidad e Tobago , Fator de Necrose Tumoral alfa/sangue , Adulto Jovem
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