RESUMO
AIM: To analyse several physicochemical properties of AH Plus (Dentsply DeTrey, Konstanz, Germany), including setting time, flow, radiopacity and the degree of conversion (DC); and to correlate the results with the source of the material: from the beginning, middle or end of the tubes in which they were supplied. METHODOLOGY: Three experimental groups were established for each property investigated. Group 1 corresponded to material taken from the beginning of tubes A and B; Group 2 corresponded to material taken from the middle of each tube; and group 3 corresponded to that from the end of each tube. The setting time, flow and radiopacity were studied according to American National Standards Institute/American Dental Association (ANSI/ADA) Specification 57. DC was determined from infrared spectra, which were recorded at 1-h intervals for the first 6 h; then, at 2-h intervals for the next 14 h; then, at 24 and 30 h. Data were analysed statistically by analysis of variance (anova), Tukey-Kramer, Kruskal-Wallis and Dunn tests, with a significance level of 5%. RESULTS: Group 1 had a significantly longer setting time (2303 ± 1058 min) (P < 0.05). Group 3 had the lowest flowability (30.0 ± 0.7 mm) and the highest radiopacity (14.85 ± 1.8 mm Al) (P < 0.05). No differences were found for the DC test (P > 0.05). CONCLUSION: The results suggest that segregation occurs between the organic and inorganic components of AH Plus sealer, thereby changing the setting time, flow and radiopacity.
Assuntos
Resinas Epóxi/química , Cimentos de Resina/química , Materiais Restauradores do Canal Radicular/química , Análise de Variância , Fenômenos Químicos , Meios de Contraste , Resinas Epóxi/normas , Hidrodinâmica , Teste de Materiais , Polimerização , Cimentos de Resina/normas , Materiais Restauradores do Canal Radicular/normasRESUMO
PURPOSE: To compare percutaneous coronary intervention (PCI) using stent implantation versus coronary artery bypass graft (CABG) in patients with multiple vessel disease with involvement of the proximal left anterior descending coronary artery (LAD). METHODS: 230 patients with multiple vessel disease and severe stenosis of the proximal LAD (113 with PCI, 117 with CABG). They were a cohort of patients from the randomised ERACI (Argentine randomized trial of percutaneous transluminal coronary angioplasty versus coronary artery bypass surgery in multivessel disease) II study. RESULTS: Both groups had similar baseline characteristics. There were no significant differences in 30 day major adverse cardiac events (death, myocardial infarction, stroke, and repeat procedures) between the strategies (PCI 2.7% v CABG 7.6%, p = 0.18). There were no significant differences in survival (PCI 96.4% v CABG 95%, p = 0.98) and survival with freedom from myocardial infarction (PCI 92% v CABG 89%, p = 0.94) at 41.5 (6) months' follow up. However, freedom from new revascularisation procedures (CABG 96.6% v PCI 73%, p = 0.0002) and frequency of angina (CABG 9.4% v PCI 22%, p = 0.025) were superior in the CABG group. CONCLUSION: Patients with multivessel disease and significant disease of the proximal LAD randomly assigned in the ERACI II trial to PCI or CABG had similar survival and survival with freedom from myocardial infarction at long term follow up. Repeat revascularisation procedures were higher in the PCI group.
Assuntos
Angioplastia Coronária com Balão/métodos , Ponte de Artéria Coronária/métodos , Doença das Coronárias/terapia , Stents , Idoso , Estudos de Coortes , Doença das Coronárias/cirurgia , Estenose Coronária/cirurgia , Estenose Coronária/terapia , Estudos Cross-Over , Feminino , Seguimentos , Mortalidade Hospitalar , Hospitalização , Humanos , Masculino , Revascularização Miocárdica/métodos , Análise de Sobrevida , Resultado do TratamentoRESUMO
OBJECTIVE: The purpose of this study was to compare percutaneous transluminal coronary revascularization (PTCR) employing stent implantation to conventional coronary artery bypass graft surgery (CABG) in symptomatic patients with multivessel coronary artery disease. BACKGROUND: Previous randomized studies comparing balloon angioplasty versus CABG have demonstrated equivalent safety results. However, CABG was associated with significantly fewer repeat revascularization procedures. METHODS: A total of 2,759 patients with coronary artery disease were screened at seven clinical sites, and 450 patients were randomly assigned to undergo either PTCR (225 patients) or CABG (225 patients). Only patients with multivessel disease and indication for revascularization were enrolled. RESULTS: Both groups had similar clinical demographics: unstable angina in 92%; 38% were older than 65 years, and 23% had a history of peripheral vascular disease. During the first 30 days, PTCR patients had lower major adverse events (death, myocardial infarction, repeat revascularization procedures and stroke) compared with CABG patients (3.6% vs. 12.3%, p = 0.002). Death occurred in 0.9% of PTCR patients versus 5.7% in CABG patients, p < 0.013, and Q myocardial infarction (MI) occurred in 0.9% PTCR versus 5.7% of CABG patients, p < 0.013. At follow-up (mean 18.5 +/- 6.4 months), survival was 96.9% in PTCR versus 92.5% in CABG, p < 0.017. Freedom from MI was also better in PTCR compared to CABG patients (97.7% vs. 93.4%, p < 0.017). Requirements for new revascularization procedures were higher in PTCR than in CABG patients (16.8% vs. 4.8%, p < 0.002). CONCLUSIONS: In this selected high-risk group of patients with multivessel disease, PTCR with stent implantation showed better survival and freedom from MI than did conventional surgery. Repeat revascularization procedures were higher in the PTCR group.
Assuntos
Angioplastia Coronária com Balão , Ponte de Artéria Coronária , Doença das Coronárias/terapia , Stents , Idoso , Argentina , Doença das Coronárias/mortalidade , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Taxa de SobrevidaRESUMO
Antituberculosis therapy commonly used for pulmonary tuberculosis in Brazil include isoniazid (440 mg), rifampicin (600 mg) both for six months plus pyrazinamide (2 g) together in the first two months. Such therapy may induce acute or chronic liver damage in some individuals. The purpose of this study is to evaluate 1096 patients treated with antituberculous drugs, being 773 males and 323 females. Clinical and laboratory signs of hepatic cell injury was present in 66 patients. Serum bilirubin and transaminase levels were evaluated in 21 (31.81%) and 45 (68.19%) respectively, with a female preponderance. Early return to normal values occurred more frequently among alcoholic drinkers and non-cigarette smokers. Liver injury was characterized as being mild and moderate and the type of injury associated was represented by pure cholestasis and hepatocanalicular lesions. Probably, rifampicin is the drug responsible for this kind of evolution aggravating the hepatotoxicity induces by isoniazid and pyrazinamide.
Assuntos
Antituberculosos/efeitos adversos , Doença Hepática Induzida por Substâncias e Drogas , Isoniazida/efeitos adversos , Pirazinamida/efeitos adversos , Rifampina/efeitos adversos , Tuberculose Pulmonar/tratamento farmacológico , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores SexuaisRESUMO
El objetivo fue demostrar las ventajas de un sistema de "recuperación posoperatoria rápida" mediante el uso de un "área de recuperación cardio-quirúrgica", con el fin de reducir costos en cirugía cardíaca. En el grupo I (n=140) se limitó la transfusión homóloga, se extubó tempranamente y se realizó monitoreo mínimamente invasivo. El grupo II (n=160) se sometió a una recuperación convencional. En el Grupo I se redujo significativamente el tiempo de intubación, la morbilidad respiratoria, el uso de monitoreo invasivo y de estudios complementarios posoperatorios, con la consecuente reducción de costos (AU)
Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Cirurgia Torácica/economia , Cirurgia Torácica/reabilitação , Análise Custo-Benefício/economia , Sala de Recuperação , Cuidados Pós-OperatóriosRESUMO
El objetivo fue demostrar las ventajas de un sistema de "recuperación posoperatoria rápida" mediante el uso de un "área de recuperación cardio-quirúrgica", con el fin de reducir costos en cirugía cardíaca. En el grupo I (n=140) se limitó la transfusión homóloga, se extubó tempranamente y se realizó monitoreo mínimamente invasivo. El grupo II (n=160) se sometió a una recuperación convencional. En el Grupo I se redujo significativamente el tiempo de intubación, la morbilidad respiratoria, el uso de monitoreo invasivo y de estudios complementarios posoperatorios, con la consecuente reducción de costos
Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Análise Custo-Benefício/economia , Cirurgia Torácica/economia , Cirurgia Torácica/reabilitação , Cuidados Pós-Operatórios , Sala de RecuperaçãoRESUMO
This study was performed to investigate the relation between total oxygen consumption (VO2) and the velocity of reheating in patients undergoing cardiopulmonary bypass with hypothermia. A total of 17 males undergoing this procedure were studied prospectively (mean age: 63 years, range: 52-72); during surgery they were cooled at 28 degrees C whole-body temperature. Before rewarming, patients were divided at random in two groups. Group A (n = 8) was reheated between 10 and 25 minutes, and group B (n = 9) between 26 and 50 minutes. In group A, VO2 expressed in ml.min-1 x m-2 increased from 76.6 +/- 6.99 at 28 degrees C until 100.0 +/- 6.72 at 34 degrees C; in group B increased from 68.4 +/- 4.55 until 129.1 +/- 4.73 at similar temperatures (analysis of variance: p < 0.01 at 28 degrees C). A greater VO2 in group B could indicate that slow rewarming would cause an even distribution of temperature with enough time for tissues to rid of their oxygen debt.
Assuntos
Circulação Extracorpórea , Temperatura Alta/uso terapêutico , Hipotermia Induzida , Consumo de Oxigênio , Idoso , Análise de Variância , Temperatura Corporal , Método Duplo-Cego , Circulação Extracorpórea/estatística & dados numéricos , Humanos , Hipotermia Induzida/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Revascularização Miocárdica/estatística & dados numéricos , Estudos Prospectivos , Fatores de TempoAssuntos
Enalapril/uso terapêutico , Hipertensão/tratamento farmacológico , Adulto , Pressão Sanguínea/efeitos dos fármacos , Brasil , Ensaios Clínicos como Assunto , Enalapril/administração & dosagem , Enalapril/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Multicêntricos como AssuntoRESUMO
Se presentaron 3 pacientes portadores de aneurismas del cayado aortico tratados con la ayuda de hipotermia profunda y paro circulatorio.Todos recuperaron la conciencia luego de isquemia cerebral de 36, 45 y 46 minutos. Dos enfermos fueron dados de alta y retornaron a su actividad normal.El tercero fallecio por sepsis a los 23 dias del postoperatorio
Assuntos
Pessoa de Meia-Idade , Humanos , Masculino , Aorta Torácica , Aneurisma Aórtico , Isquemia Encefálica , HipotermiaRESUMO
Se presenta una serie de 81 enfermos a los que se les efectuo interrupcion del flujo en la vena cava inferior haciendo hincapie en las indicaciones, evolucion y complicaciones
Assuntos
Adulto , Pessoa de Meia-Idade , Humanos , Masculino , Feminino , Embolia Pulmonar , Veia Cava InferiorRESUMO
La incidencia de complicaciones en 477 implantes endocavitarios de marcapasos definitivos fue significativamente menor en aquellos en los que se utilizaron electrodos con aletas (3,7% vs. 18,1%)
Assuntos
Humanos , Eletrodos , Marca-Passo ArtificialRESUMO
El aumento en el gradiente alveoloarterial para el oxigeno encontrado en este estudio fue el princial factor influenciado por la anestesia general y la toracotomia. Probablemente, ambos, incrementaron el valor de la admision venosa y la hipoxemia observada 24 horas despues de la operacion. La disminucion de la PO2 arterial encontrada por otros investigadores, podria estar relacionada con el tipo de pacientes, principalmente los afectados de lesion mitral y sometidos a la cirugia cardiaca con circulacion extracorporea
Assuntos
Adolescente , Adulto , Humanos , Masculino , Feminino , Circulação Extracorpórea , Insuficiência Cardíaca , Defeitos dos Septos CardíacosRESUMO
Se presentaron 3 pacientes portadores de aneurismas del cayado aortico tratados con la ayuda de hipotermia profunda y paro circulatorio.Todos recuperaron la conciencia luego de isquemia cerebral de 36, 45 y 46 minutos. Dos enfermos fueron dados de alta y retornaron a su actividad normal.El tercero fallecio por sepsis a los 23 dias del postoperatorio
Assuntos
Pessoa de Meia-Idade , Humanos , Masculino , Aneurisma Aórtico , Aorta Torácica , Hipotermia , Isquemia EncefálicaRESUMO
Se presenta una serie de 81 enfermos a los que se les efectuo interrupcion del flujo en la vena cava inferior haciendo hincapie en las indicaciones, evolucion y complicaciones
Assuntos
Adulto , Pessoa de Meia-Idade , Idoso , Humanos , Masculino , Feminino , Embolia Pulmonar , Veia Cava InferiorRESUMO
La incidencia de complicaciones en 477 implantes endocavitarios de marcapasos definitivos fue significativamente menor en aquellos en los que se utilizaron electrodos con aletas (3,7% vs. 18,1%)
Assuntos
Humanos , Eletrodos , Marca-Passo ArtificialRESUMO
El aumento en el gradiente alveoloarterial para el oxigeno encontrado en este estudio fue el princial factor influenciado por la anestesia general y la toracotomia. Probablemente, ambos, incrementaron el valor de la admision venosa y la hipoxemia observada 24 horas despues de la operacion. La disminucion de la PO2 arterial encontrada por otros investigadores, podria estar relacionada con el tipo de pacientes, principalmente los afectados de lesion mitral y sometidos a la cirugia cardiaca con circulacion extracorporea