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1.
Eur J Appl Physiol ; 2023 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-38032386

RESUMO

The study aimed to investigate the effects of sodium bicarbonate (NaHCO3) intake with divergent verbal and visual information on constant load cycling time-to-task failure, conducted within the severe intensity domain. Fifteen recreational cyclists participated in a randomized double-blind, crossover study, ingesting NaHCO3 or placebo (i.e., dextrose), but with divergent information about its likely influence (i.e., likely to induce ergogenic, inert, or harmful effects). Performance was evaluated using constant load cycling time to task failure trial at 115% of peak power output estimated during a ramp incremental exercise test. Data on blood lactate, blood acid-base balance, muscle electrical activity (EMG) through electromyography signal, and the twitch interpolation technique to assess neuromuscular indices were collected. Despite reduced peak force in the isometric maximal voluntary contraction and post-effort peripheral fatigue in all conditions (P < 0.001), neither time to task failure, EMG nor, blood acid-base balance differed between conditions (P > 0.05). Evaluation of effect sizes of all conditions suggested that informing participants that the supplement would be likely to have a positive effect (NaHCO3/Ergogenic: 0.46; 0.15-0.74; Dextrose/Ergogenic: 0.45; 0.04-0.88) resulted in improved performance compared to control. Thus, NaHCO3 ingestion consistently induced alkalosis, indicating that the physiological conditions to improve performance were present. Despite this, NaHCO3 ingestion did not influence performance or indicators of neuromuscular fatigue. In contrast, effect size estimates indicate that participants performed better when informed that they were ingesting an ergogenic supplement. These findings suggest that the apparently ergogenic effect of NaHCO3 may be due, at least in part, to a placebo effect.

2.
Biol Sport ; 40(4): 993-1001, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37867732

RESUMO

This study compared the effects of two sprint-jump training programmes, performed on either sand or grass surfaces, on the sprint and jump performance of elite young soccer players over an 8-week training period. Fifteen under-20 soccer players were randomly allocated to the sand (n = 7) or grass (n = 8) group. Athletes performed 12 training sessions, comprising vertical and horizontal jump exercises, and linear and change-of-direction (COD) sprint drills. Pre- and post-measurements were completed in the following order: vertical jump, sprint speed at 10 m and 17 m, curve sprint (CS), and modified Zigzag COD tests. Between-group differences were determined using a two-way ANOVA with repeated measures and effect sizes (ES). No improvements in jump performance were found in either group. Significant increases were observed in the sand group for acceleration in 0-10 m and for 10- and 17-m linear sprint velocity (ES = 1.15, 1.16, and 1.81, respectively; P < 0.05). In contrast, no significant differences were detected for acceleration and linear sprint velocity in the grass group, comparing pre- and post-tests (ES ranging from 0.01 to 0.47; P > 0.05). Both sand and grass groups revealed similar increases in the CS and COD velocities after the training period (ES ranging from 0.98 to 1.93; P < 0.05). In conclusion, sprint-jump training programmes performed on both grass and sand surfaces elicited significant improvements in CS and COD performances, whereas acceleration and linear sprint velocity increased only in the sand group, after a short-term training period. The sand training surface was proven to be a practical strategy to improve sprint performance in all its forms in soccer players, which is of great interest and importance for coaches and sport scientists working in elite soccer.

3.
Mol Genet Genomics ; 298(3): 735-754, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37017807

RESUMO

Trichoderma atroviride and Trichoderma harzianum are widely used as commercial biocontrol agents against plant diseases. Recently, T. harzianum IOC-3844 (Th3844) and T. harzianum CBMAI-0179 (Th0179) demonstrated great potential in the enzymatic conversion of lignocellulose into fermentable sugars. Herein, we performed whole-genome sequencing and assembly of the Th3844 and Th0179 strains. To assess the genetic diversity within the genus Trichoderma, the results of both strains were compared with strains of T. atroviride CBMAI-00020 (Ta0020) and T. reesei CBMAI-0711 (Tr0711). The sequencing coverage value of all genomes evaluated in this study was higher than that of previously reported genomes for the same species of Trichoderma. The resulting assembly revealed total lengths of 40 Mb (Th3844), 39 Mb (Th0179), 36 Mb (Ta0020), and 32 Mb (Tr0711). A genome-wide phylogenetic analysis provided details on the relationships of the newly sequenced species with other Trichoderma species. Structural variants revealed genomic rearrangements among Th3844, Th0179, Ta0020, and Tr0711 relative to the T. reesei QM6a reference genome and showed the functional effects of such variants. In conclusion, the findings presented herein allow the visualization of genetic diversity in the evaluated strains and offer opportunities to explore such fungal genomes in future biotechnological and industrial applications.


Assuntos
Trichoderma , Filogenia , Trichoderma/genética , Genômica
4.
J Strength Cond Res ; 37(9): 1828-1833, 2023 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-36723059

RESUMO

ABSTRACT: Pereira, LA, Freitas, TT, Zabaloy, S, Ferreira, RCA, Silva, ML, Azevedo, PHSM, and Loturco, I. Sprint and jump training on sand versus grass surfaces: effects on the physical performance of young soccer players. J Strength Cond Res 37(9): 1828-1833, 2023-The aims of this study were to (a) examine the effects of a 6-week sand training program including both sprint and jump exercises on the speed-related and vertical jump performance of elite young soccer players and (b) compare the changes induced by a sand training scheme with those induced by a similar training program (in volume, intensity, and exercise types) performed on grass. Twenty-four under-20 soccer players were randomly allocated to 2 training groups, as follows: "sand" ( n = 12) or "grass" ( n = 12) groups. Athletes performed squat and countermovement jumps, linear sprints, and Zigzag change-of-direction speed tests at pre-, mid- (after 6 training sessions), and postintervention (after 12 training sessions). Both groups exhibited similar increases in the vertical jump and Zigzag performance after the 6-week training period ( p values ranging from 0.0001 to 0.025; effect size ranging from 1.05 to 3.78, for main effect of time). No significant changes were detected for the linear sprint velocity for both the groups ( p values ranging from 0.079 to 1.00; effect size ranging from 0.07 to 0.65, for main effect of time). In summary, training on sand or grass surfaces resulted in similar improvements in the physical performance of elite young soccer players. This study confirms the current evidence on the effectiveness of both soft and harder training surfaces in improving the sprint and jump performance of team-sport athletes.


Assuntos
Desempenho Atlético , Treinamento Resistido , Corrida , Futebol , Humanos , Força Muscular , Desempenho Físico Funcional , Treinamento Resistido/métodos , Areia
5.
Microorganisms ; 11(2)2023 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-36838413

RESUMO

Salmonella Typhimurium is the most frequent serovar in pigs and causes infections in humans. However, the dosage used for experimentation is not well defined. The present study aimed to evaluate a dosage for oral inoculation with Salmonella Typhimurium to assess immunological and growth performance alterations in pigs. Gilts were randomly allocated into one of three experimental treatments: no Salmonella Typhimurium inoculation (Basal), or oral inoculation of 1 × 108 or 1.5 × 108 colony-forming units of Salmonella Typhimurium. Growth rate, rectal temperature, and fecal Salmonella shedding were recorded. Blood samples were taken. Inoculated pigs shed the bacteria for up to 7 days, but no differences were observed between the groups. No differences were observed in rectal temperature, body weight, or average daily feed intake. However, reductions in average daily gain (-17 and -22%) and feed efficiency (-14 and -20%) were observed in pigs inoculated with 1 × 108 and 1.5 × 108 colony-forming units, respectively. The hemoglobin and hematocrit concentrations increased in challenged pigs compared to Basal pigs. The oral dosage of 1.5 × 108 colony-forming units of Salmonella Typhimurium is suitable for activating the immune system of pigs and assessing the impact of Salmonella on pig performance.

6.
Biol Sport ; 40(1): 193-200, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36636185

RESUMO

We aimed to evaluate the effect of 4 weeks of plyometric training (PT), performed in the pre-competitive period, on the vertical jump performance of professional volleyball athletes. We recruited 17 professional female volleyball players (age: 19 ± 3 years; weight: 67.2 ± 5.50 kg; height: 1.81 ± 0.22 m; body fat: 14.4 ± 2.12%; squat 1RM test: 75.5 ± 7.82 kg; training time experience: 6.2 ± 3.4 years) to participate in four weeks of training and assessments. They were divided into an experimental group (EG = 9) and a control group (CG = 8). Both groups were submitted to friendly matches, technical, tactical and resistance training (4 weeks/˜9 sessions per week), and internal load monitoring was carried out. The EG performed PT twice a week. At the beginning and end of the four weeks, jump tests were performed. The main findings are: 1) PT when incorporated into the pre-competitive period can induce greater improvements in jumping performance (EG = 28.93 ± 3.24 cm to 31.67 ± 3.39 cm; CG = 27.91 ± 4.64 cm to 28.97 ± 4.58 cm; when comparing the percentage delta, we found a difference between groups with ES of 1.04 and P = 0.02); 2) this result is observed when the training load is similar between groups and increases over the weeks, respecting the linear progression principle. Therefore, including plyometric training in the preparatory period for volleyball, with low monotony and training strain increment, is an effective strategy for further CMJ performance improvement.

7.
Sci Rep ; 13(1): 855, 2023 01 16.
Artigo em Inglês | MEDLINE | ID: mdl-36646725

RESUMO

The effect of different proportions of cactus pear (Opuntia ficus-indica Mill) silage (CPS) and intermittent water supply (IWS) to crossbreed goats' diets on carcass traits and meat quality were evaluated. The IWS caused a reduction (p = 0.03) in the percentage of leg fat in the animals. The rib eye area, carcass weight, and physical-chemical characteristics were not affected (p > 0.05) by the CPS or IWS. The IWS reduced (p = 0.04) the elongase enzyme activity. The CPS inclusion in the diet reduced C22:0 (p = 0.01), some branched-chain fatty acid (BCFA), C20:1 (p = 0.03), c13-C18:1 (p = 0.01) fatty acids. Therefore, in situations of water scarcity, an intermittent water supply of up to 48 h and diets with up to 42% cactus pear silage, can be adopted in goat feedlot, without affecting carcass traits and meat quality.


Assuntos
Opuntia , Silagem , Animais , Ração Animal/análise , Cabras , Dieta/veterinária , Ácidos Graxos , Carne/análise , Abastecimento de Água
8.
São Paulo; s.n; 2023. 72 p.
Tese em Português | LILACS | ID: biblio-1512870

RESUMO

Esta dissertação destaca a importância da indústria da construção civil na economia global e enfatiza o papel crucial do setor no gerenciamento e minimização do desperdício de resíduos gerados em uma obra de médio porte vertical com finalidade residencial, que é um passo além do desperdício de matéria prima que resulta na geração de resíduos. Os objetivos específicos é identificar a quantidade de resíduo de construção civil (RCC) gerado por m² em cada uma das obras estudadas, caracterizar os fatores que influenciam no desperdício de RCC e por fim, elaborar um guia de boas práticas na construção civil. Devido ao aumento das atividades construtivas, a geração de resíduos sólidos tem crescido proporcionalmente, o que demanda estudos aprofundados sobre a gestão desses resíduos no setor. A falta de capacitação técnica e conscientização dos profissionais do setor tem contribuído significativamente para o desperdício de matéria-prima e a geração excessiva de resíduos. A construção civil é a maior consumidora de recursos naturais não renováveis, e o uso de métodos e procedimentos obsoletos, ainda hoje agrava ainda mais o problema do desperdício de resíduos. No contexto da região de Mogi das Cruzes (SP), a dissertação identifica várias possibilidades de destinação final dos resíduos gerados na construção civil, evidenciando o potencial de reaproveitamento e a contribuição para a redução da pressão antropogênica sobre o meio ambiente nesta localidade. O objetivo principal desta pesquisa é contribuir para a área de conhecimento da construção civil, aumentando a eficiência nos canteiros de obras e, consequentemente, reduzindo o desperdício de resíduos. Com foco na questão do desperdício de resíduos, sabendo que este pode ser reaproveitado na própria obra ou enviado a usinas transformadoras foi possível. A dissertação reforça a importância de desenvolver e implementar práticas sustentáveis no setor de construção civil, a fim de garantir a preservação dos recursos naturais para as gerações futuras e promover uma abordagem mais responsável e consciente no gerenciamento dos resíduos gerados nesta indústria. Este projeto gerou, como um produto um guia de boas práticas na construção civil de obras residenciais verticais, concluindo que há possibilidade de promover avanços na melhoria da qualidade da mão de obra em todos os níveis, reduzindo o impacto ambiental em concordância com o desenvolvimento sustentável do setor.


This dissertation highlights the importance of the civil construction industry in the global economy and emphasizes the crucial role of the sector in the management and minimization of the waste of waste generated in a medium-sized vertical work with a residential purpose, which is a step beyond the waste of raw materials. which results in the generation of waste. The specific objectives are to identify the amount of civil construction waste (RCC) generated per m² in each of the works studied, to characterize the factors that influence the waste of RCC and finally, to elaborate a guide of good practices in civil construction. Due to the increase in construction activities, the generation of solid waste has grown proportionally, which demands in-depth studies on the management of this waste in the sector. The lack of technical training and awareness of professionals in the sector has contributed significantly to the waste of raw materials and the excessive generation of waste. Civil construction is the biggest consumer of non-renewable natural resources, and the use of obsolete methods and procedures, even today, further aggravates the problem of lost waste. In the context of the region of Mogi das Cruzes (SP), the dissertation identifies several possibilities for the final destination of waste generated in civil construction, highlighting the potential for reuse and the contribution to reducing anthropogenic pressure on the environment in this location. The main objective of this research is to contribute to the area of knowledge of civil construction, increasing efficiency at construction sites and, consequently, reducing waste. Focusing on the issue of lost waste, knowing that it can be reused on site or sent to processing plants was possible. The dissertation reinforces the importance of developing and implementing sustainable practices in the civil construction sector, in order to guarantee the preservation of natural resources for future generations and to promote a more responsible and conscious approach in the management of waste generated in this industry. This project generated, as a product, a guide to good practices in the civil construction of vertical residential works, concluding that there is the possibility of promoting advances in improving the quality of labor at all levels, reducing the environmental impact in accordance with sustainable development of the sector.


Assuntos
Resíduos Sólidos , Indústria da Construção , Gerenciamento de Resíduos
11.
Biol Sport ; 39(2): 443-449, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35309524

RESUMO

The purpose of this study was to evaluate the effects of altering the duration of the eccentric phase in isotonic contractions on muscle hypertrophy and strength of the quadriceps femoris. Ten healthy young adults (8 men and 2 women: Height: 173.3 ± 9.6 cm: Body mass: 69.84 ± 10.88 kg; Body fat: 19.47 ± 8.42%; Age: 25.3 ± 4.8 years) performed unilateral isotonic knee extension exercise, whereby each leg was randomly allocated to perform the eccentric phase of movement with a duration of either 2 seconds (G2S) or 4 seconds (G4S). Both conditions carried out the concentric phase of each repetition at a 1 second duration with no rest in the transition phases. Each condition performed 5 sets using 70% of 1 repetition maximum until muscle failure with 3 minutes of rest between sets for 8 weeks. The change in muscle strength was assessed by 1RM knee extension and muscle thickness was assessed by A-mode ultrasound. For each outcome variable, linear mixed-effects models were fit using restricted maximum likelihood. Hedges' g effect sizes were calculated to provide insights into the magnitude of effects. Results showed all muscles increased in size over time; mean effects were similar in all muscles except for the vastus medialis, which favored the G4S condition. Conversely, only a trivial and highly variable effect was observed between interventions for strength gain. Our results suggest different eccentric durations produce similar increases in hypertrophy of the vastus lateralis and rectus femoris; however, the vastus medialis showed greater growth from the slower eccentric duration. Eccentric duration did not differentially affect strength-related adaptations.

12.
Biosci. j. (Online) ; 38: e38001, Jan.-Dec. 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1361655

RESUMO

This study aimed to determine the frequency of infection by intestinal protozoa diagnosed in patients from a clinical analysis laboratory in Maceió, Alagoas, Brazil. This was a retrospective descriptive study, using a database of stool examination results from July to December 2015. The study population consisted of males and females of all ages, from the greater area of Alagoas. Data on epidemiological variables such as age and gender were obtained using a collection instrument. Protozoan species were identified from stool examinations. Results on the prevalence of intestinal parasites are described as simple and relative frequencies. We examined a total of 1277 stool samples, of which 12.69% were positive for one or more protozoa. 43.83% were from men and 56.17% were from women. Endolimax nana was the most prevalent (59.22%) protozoan species followed by Entamoeba coli (23.45%). Although non-pathogenic, they indicate fecal contamination of drinking water. The highest number (23.46%) of infected individuals was observed among children in the 0 to 11 years age group. A high prevalence (93.83%) of monoparasitism was noted. We concluded that there was a high frequency of infection and a high prevalence of E. nana. Infections were more common in women than in men. Our results emphasize the need for preventive measures to control intestinal parasitic infections.


Assuntos
Doenças Parasitárias/epidemiologia , Infecções/parasitologia
13.
J Strength Cond Res ; 36(3): 862-866, 2022 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-32168177

RESUMO

ABSTRACT: Loturco, I, Pereira, LA, Reis, VP, Abad, CCC, Freitas, TT, Azevedo, PHSM and Nimphius, S. Change of direction performance in elite players from different team sports. J Strength Cond Res 36(3): 862-866, 2022-The primary aim of this study was to examine the differences in change of direction (COD) deficit between elite futsal, soccer, handball, and rugby players. A secondary aim was to compare the performance in both COD and linear speed tests among these athletes. One-hundred sixty-one elite male players from 4 team sports performed a 20-m linear sprint speed and a Zigzag COD speed test. The COD deficit was calculated as the difference between linear and Zigzag test velocities. Differences in COD speed, COD deficit, and sprint velocity were assessed via 1-way analysis of variance. The significance level was set at p < 0.05. Soccer players displayed significantly lower performance than the remaining team sports, and rugby players performed better than all the other groups in the Zigzag COD test. Moreover, the COD deficit was significantly higher in soccer players in comparison with the other disciplines (p < 0.05). No differences were observed in the COD deficit among rugby, futsal, and handball players (p > 0.05). In summary, soccer players were slower than futsal, handball, and rugby players to change direction and presented the greatest COD deficit magnitude. By contrast, the fastest athletes in the COD speed test (rugby players) were not more effective than futsal and handball players at changing direction (as they exhibited similar levels of COD deficit). Coaches should be aware of this evidence, which reinforces previous findings, indicating that very specialized training strategies might be required to improve COD performance in professional athletes.


Assuntos
Desempenho Atlético , Corrida , Futebol , Atletas , Humanos , Masculino , Esportes de Equipe
14.
Int J Sports Med ; 43(4): 305-316, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34749417

RESUMO

Training-intensity distribution (TID) is considered the key factor to optimize performance in endurance sports. This systematic review aimed to: I) characterize the TID typically used by middle-and long-distance runners; II) compare the effect of different types of TID on endurance performance and its physiological determinants; III) determine the extent to which different TID quantification methods can calculate same TID outcomes from a given training program. The keywords and search strategy identified 20 articles in the research databases. These articles demonstrated differences in the quantification of the different training-intensity zones among quantification methods (i. e. session-rating of perceived exertion, heart rate, blood lactate, race pace, and running speed). The studies that used greater volumes of low-intensity training such as those characterized by pyramidal and polarized TID approaches, reported greater improvements in endurance performance than those which used a threshold TID. Thus, it seems that the combination of high-volume at low-intensity (≥ 70% of overall training volume) and low-volume at threshold and high-intensity interval training (≤ 30%) is necessary to optimize endurance training adaptations in middle-and long-distance runners. Moreover, monitoring training via multiple mechanisms that systematically encompasses objective and subjective TID quantification methods can help coaches/researches to make better decisions.


Assuntos
Treino Aeróbico , Treinamento Intervalado de Alta Intensidade , Corrida , Treino Aeróbico/métodos , Humanos , Consumo de Oxigênio , Resistência Física/fisiologia , Corrida/fisiologia
15.
Rev. med. (Säo Paulo) ; 101(1): e-192193, jan.-fev. 2022.
Artigo em Inglês, Português | LILACS-Express | LILACS | ID: biblio-1381289

RESUMO

Introdução: O Coronavírus é um vírus zoonótico de RNA, tratando-se também de uma família de vírus que causam infecções respiratórias, em que um dos tipos conhecidos é o SARS-CoV-2, que é um novo coronavírus descrito no final de 2019, sendo responsável por provocar a doença chamada de COVID-19. Além do trato respiratório, tal patologia pode afetar vários sistemas orgânicos e dentre esses, o sistema neuromuscular tem sido apontado como alvo do SARS-CoV-2. Objetivo: Verificar se há relação entre a COVID-19 e o surgimento de doenças neuromusculares. Metodologia: Revisão sistemática pelo método PRISMA, com coleta de dados realizada nas bases PubMed e BVS, verificando a relação entre a COVID-19 e o surgimento ou intensificação das doenças neuromusculares. Os artigos coletados foram publicados entre janeiro de 2020 e março de 2021. Foram encontrados 1366 artigos e aprovados 56 para a revisão sistemática. Resultados: 56 estudos apontaram ligação entre a COVID-19 e o desenvolvimento de patologias neuromusculares, destacando-se: Síndrome de Guillain-Barré e suas variações (n=37), Miastenia de Gravis (n=4), Mielite (n=2). Discussão: Em relação a Síndrome de Guillain-Barré e sua associação com a COVID-19, observou-se que os principais sinais e sintomas neuromusculares relatados foram: déficits quantitativos dos reflexos (hiporreflexia ou arreflexia), parestesia, paralisia, diminuição da força muscular, dormência e formigamento. Por conseguinte, notou-se que há diversas relações entre a COVID-19 e o desenvolvimento de doenças ou síndromes neuromusculares. Conclusão: É possível perceber que há forte indícios da relação entre a fisiopatologia da COVID-19 e o surgimento de síndromes neuromusculares, sendo a Síndrome de Guillain-Barré a disfunção mais relatada em diferentes localidades do mundo. Nesse sentido, é interessante o desenvolvimento de pesquisas com maior tamanho amostral, bem como, necessidade de compreensão do mecanismo de ação viral sobre o sistema nervoso, a fim de obter tratamentos mais eficientes para esses quadros clínicos. [au]


Introduction: Coronaviruses are zoonotic RNA viruses, and are also a family of viruses that cause respiratory infections. One of the known types is SARS-CoV-2, a new coronavirus described in late 2019, responsible for causing the COVID-19. Besides the respiratory tract, such pathology can affect several organ systems and among these, the neuromuscular system has been pointed out as a target of SARS-CoV-2. Objective: To determine whether there is a relationship between COVID-19 and the emergence of neuromuscular diseases. Methodology: Systematic review using the PRISMA method, with data collection carried out in PubMed and BVS, verifying the relationship between COVID-19 and the emergence or intensification of neuromuscular diseases. The collected articles were published between January 2020 and March 2021. A total of 1366 articles were found and 56 were approved for the systematic review. Results: 56 studies pointed out a link between COVID-19 and the development of neuromuscular pathologies, highlighting: Guillain-Barré syndrome and its variations (n=37), Gravis myasthenia (n=4), Myelitis (n=2). Discussion: Regarding Guillain-Barré Syndrome and its association with COVID-19, it was observed that the main neuromuscular signs and symptoms reported were: quantitative reflex deficits (hyporeflexia or arreflexia), paresthesia, paralysis, decreased muscle strength, numbness and tingling. Therefore, it was noted that there are several relationships between COVID-19 and the development of neuromuscular diseases or syndromes. Conclusion: It is possible to see that there is strong evidence of a relationship between the pathophysiology of COVID-19 and the emergence of neuromuscular syndromes, with Guillain-Barré Syndrome being the most reported dysfunction in different locations around the world. In this sense, it is interesting the development of research with a larger sample size, as well as the need to understand the mechanism of viral action on the nervous system in order to obtain more efficient treatments for these clinical pictures [au]

16.
Braz. J. Pharm. Sci. (Online) ; 58: e19500, 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1383990

RESUMO

Abstract The pursuit of quality of life, which has become marked in recent years, has translated into important population health benefits. This study assessed the quality of life of patients with type 2 diabetes (T2DM) who received pharmaceutical care, and their satisfaction with the service provided in community pharmacies. This single blind, randomized controlled clinical trial included 100 patients. The intervention group (N=47) received pharmaceutical care by a clinical pharmacist and the control group (N=42) received standard care. The Quality of Life Diabetes Questionnaire (DQOL) was used to measure all participants´ quality of life at study enrollment and six months later. Satisfaction of the participants in the intervention group was measured using a validated 14-items questionnaire. At the end of the study, participants in the intervention group had a statistically significant improvement in DQOL scores ( -0.62 x 1.57, p < 0.001) and were highly satisfied with the intervention (96% excellent satisfaction scores). Pharmaceutical care practice was associated with high satisfaction and increased quality of life scores in T2DM patients. These results underscore the important role of pharmacists to improve the health of diabetic patients.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pacientes/classificação , Qualidade de Vida , Ensaio Clínico Controlado Aleatório , Padrões de Prática dos Farmacêuticos/ética , Assistência Farmacêutica , Satisfação do Paciente , Diabetes Mellitus Tipo 2/patologia
17.
PLoS One ; 16(12): e0261554, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34919579

RESUMO

The objective of this study were to examine the effects of diets containing spineless cactus associated with hays of different legume species [gliricidia (Gliricidia sepium), "catingueira" (Caesalpinia bracteosa), "sabiá" (Mimosa caesalpiniifolia Benth) and "catanduva" (Piptadenia moniliformis Benth)] on the intake, digestibility, performance and carcass traits of lambs. Twenty-four ½ Santa Inês × ½ Soinga lambs with an average body weight of 21.4 ± 2.53 kg were distributed into four treatments in a completely randomized design. Treatments consisted of diets formulated with the association of spineless cactus (Opuntia ficus-indica Mill) and hay of four legume species, namely, "catanduva", "sabiá" "catingueira" and gliricidia. The lowest intakes (P<0.05) of dry matter (DM), organic matter (OM), neutral detergent fiber (NDF) and total carbohydrates occurred in the animals that received the diet containing catingueira hay. However, there were no diet effects (P>0.05) on the intakes of crude protein (CP), ether extract and non-fibrous carbohydrates. The diets also did not change (P>0.05) the weight gain (0.197 kg/day) or final weight (33.18 kg) of the lambs or the apparent digestibility coefficients of DM, OM, CP and NDF. Consequently, the parameters of live weight at slaughter (34.10 kg), hot carcass weight (14.81 kg), cold carcass weight (14.66 kg), hot carcass yield (45.60%) and cold carcass yield (45.07%) exhibited the no response to treatment. In addition to these variables, the diets also did not influence subcutaneous fat thickness (2.54 mm), longissimus muscle area (13.34 cm2), morphometric measurements of the carcass, or the proportions of muscle and fat. Therefore, legume hays associated with spineless cactus can be used to feed ½ Santa Inês × ½ Soinga lambs in the feedlot, as this strategy provides heavy animals at the time of slaughter and carcasses with desirable degrees of muscularity and adiposity.


Assuntos
Ração Animal/análise , Fenômenos Fisiológicos da Nutrição Animal/fisiologia , Cactaceae , Dieta/veterinária , Fabaceae , Adiposidade/fisiologia , Animais , Masculino , Músculos Paraespinais/fisiologia , Ovinos , Aumento de Peso
18.
Int J Exerc Sci ; 14(2): 295-303, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34055152

RESUMO

The purpose of this study was to verify whether cooling between sets during high-intensity resistance exercise improves physical performance and to compare performance among different sites of cooling. It is important because delaying the muscular fatigue could improve total volume at a training session which could lead to greater hypertrophy. Nine healthy and recreational resistance training experienced men, performed six tests of a biceps curl exercise on different days. The first test was the one-repetition maximum test (1RM). Following, we applied five sessions, in crossover and randomized (counter-balanced) design. The subjects received different cooling strategies in each session for 1-min (inter-set rest interval): Control (C) (no Cooling); Palm Cooling (PC); Neck Cooling (NC); Local Cooling (LC) or Tunnel Temperature Cooling (TTC). We analyzed the maximum number of repetitions and the rating of perceived exertion (RPE). The Bayesian analysis showed that no cooling strategy was able to improve performance compared to control, and just NC, when compared to control, showed a 71% probability of increasing the total volume of repetitions. Also, RPE was not modulated by any cooling strategy compared to control, but NC has a chance to reduce individuals' RPE by 52%. In conclusion, no cooling strategy was efficient to improve physical performance during a high-intensity resistance exercise.

19.
Sci Rep ; 11(1): 11148, 2021 05 27.
Artigo em Inglês | MEDLINE | ID: mdl-34045508

RESUMO

This study investigated the effects of inspiratory muscle pre-activation (IMPA) on the interactions among the technical-tactical, physical, physiological, and psychophysiological parameters in a simulated judo match, based on the centrality metrics by complex network model. Ten male athletes performed 4 experimental sessions. Firstly, anthropometric measurements, maximal inspiratory pressure (MIP) and global strenght of the inspiratory muscles were determined. In the following days, all athletes performed four-minute video-recorded judo matches, under three conditions: without IMPA (CON), after IMPA at 15% (IMPA15), and at 40% (IMPA40) of MIP using an exerciser device. Blood lactate, heart rate and rating of perceived exertion were monitored, and the technical-tactical parameters during the match were related to offensive actions and the time-motion. Based on the complex network, graphs were constructed for each scenario (CON, IMPA15, and IMPA40) to investigate the Degree and Pagerank centrality metrics. IMPA40 increased the connectivity of the physical and technical-tactical parameters in complex network and highlighted the combat frequency and average combat time in top-five ranked nodes. IMPA15 also favoured the interactions among the psychophysiological, physical, and physiological parameters. Our results suggest the positive effects of the IMPA, indicating this strategy to prepare the organism (IMPA15) and to improve performance (IMPA40) in judo match.


Assuntos
Desempenho Atlético/fisiologia , Músculos Respiratórios/fisiologia , Atletas , Força da Mão/fisiologia , Frequência Cardíaca/fisiologia , Humanos , Ácido Láctico/sangue , Masculino , Artes Marciais , Modelos Teóricos , Adulto Jovem
20.
J Dairy Res ; 88(2): 166-169, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-34036927

RESUMO

We investigated the effects of pathogens associated with subclinical intramammary infections on yield, composition and quality indicators of goat milk. By means of a longitudinal study, individual half udder milk samples (n = 132) were collected at different lactation periods and assessed for milk yield and physicochemical composition, somatic cell count (SCC), total bacteria count (TBC) and microbiological culture. Staphylococci species accounted for the great majority of the isolates (96.1%). Intramammary infections significantly reduced fat and total solids in goat milk and increased both SCC and TBC. However, these indicators were significantly higher in udder halves affected by S. aureus compared with other staphylococci species.


Assuntos
Infecções Bacterianas/veterinária , Doenças das Cabras/microbiologia , Mastite/veterinária , Leite/química , Leite/microbiologia , Animais , Infecções Bacterianas/microbiologia , Carga Bacteriana/veterinária , Contagem de Células/veterinária , Feminino , Cabras , Lactação , Estudos Longitudinais , Glândulas Mamárias Animais/microbiologia , Mastite/microbiologia , Leite/citologia , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/veterinária , Staphylococcus aureus/isolamento & purificação
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