RESUMO
Background: Cutaneous papillomas are benign proliferative neoplasms. The aetiology and pathogenesis of the disease are very complex. Papillomatosis lesions can be detected anywhere on the body, frequently appearing on the surface of the head, neck, teats, udder, external genital mucosa and upper part of the gastrointestinal tract. The disease is not life threatening but due to loss of productivity, owners often cull animals with papillomatosis. The relationships between trace elements, heavy metals and cancer are still researching. The aim of this study was the evaluation of the relationships between trace elements and antioxidant metabolism, and cutaneous papillomatosis, in cattle.Materials, Methods & Results: Eleven cattle with cutaneous papillomatosis and 10 healthy cattle constituted the study group and control group, respectively. Clinical examinations were performed on all animals. Blood samples were collected and Cr, Cu, Fe, Mg, Mn, Se, Zn, As, B, Ni, Si and Co levels were determined. The analyses were conducted with an inductively coupled plasma-optical emission spectrophotometer. In addition, catalase (CAT), glutathione (GSH), malondialdehyde (MDA) and ceruloplasmin (Cp) concentrations were measured. The Ni, Si and MDA levels of the study group were significantly higher than those of the control group (P < 0.05) but the Se levels of the study group were significantly lower than in the control group (P < 0.05). The normality of the data was determined with the Shapiro-Wilk Test and the Independent Samples t-Test or Mann-Whitney U test was used for statistical comparison of the groups.Discussion: Trace elements are essential components of biological systems. The levels of trace elements, such as Cu, Co, I, Se, Zn and Mn, which are affected by grazing activity, influence ruminants reproductive performance and other production parameters.[...]
Assuntos
Animais , Bovinos , Antioxidantes/análise , Antioxidantes/metabolismo , Neoplasias Cutâneas/imunologia , Neoplasias Cutâneas/veterinária , Oligoelementos/análise , Papiloma/veterinária , ImunidadeRESUMO
Background: Cutaneous papillomas are benign proliferative neoplasms. The aetiology and pathogenesis of the disease are very complex. Papillomatosis lesions can be detected anywhere on the body, frequently appearing on the surface of the head, neck, teats, udder, external genital mucosa and upper part of the gastrointestinal tract. The disease is not life threatening but due to loss of productivity, owners often cull animals with papillomatosis. The relationships between trace elements, heavy metals and cancer are still researching. The aim of this study was the evaluation of the relationships between trace elements and antioxidant metabolism, and cutaneous papillomatosis, in cattle.Materials, Methods & Results: Eleven cattle with cutaneous papillomatosis and 10 healthy cattle constituted the study group and control group, respectively. Clinical examinations were performed on all animals. Blood samples were collected and Cr, Cu, Fe, Mg, Mn, Se, Zn, As, B, Ni, Si and Co levels were determined. The analyses were conducted with an inductively coupled plasma-optical emission spectrophotometer. In addition, catalase (CAT), glutathione (GSH), malondialdehyde (MDA) and ceruloplasmin (Cp) concentrations were measured. The Ni, Si and MDA levels of the study group were significantly higher than those of the control group (P < 0.05) but the Se levels of the study group were significantly lower than in the control group (P < 0.05). The normality of the data was determined with the Shapiro-Wilk Test and the Independent Samples t-Test or Mann-Whitney U test was used for statistical comparison of the groups.Discussion: Trace elements are essential components of biological systems. The levels of trace elements, such as Cu, Co, I, Se, Zn and Mn, which are affected by grazing activity, influence ruminants reproductive performance and other production parameters.[...](AU)
Assuntos
Animais , Bovinos , Papiloma/veterinária , Neoplasias Cutâneas/imunologia , Neoplasias Cutâneas/veterinária , Oligoelementos/análise , Antioxidantes/análise , Antioxidantes/metabolismo , ImunidadeRESUMO
Background: Some blood parameters have diagnostic and prognostic importance for the infections in human medicine. However, there is insufficient research regarding the importance of blood parameters and their correlations in veterinary medicine. Increased blood cell distribution width (RDW) and platelet activity can link with the important inflammatory markers. The main objective of the present study was the evaluation of the relationship among some important blood parameters namely RDW, platelet count (PLT), platelet distribution width (PDW), mean platelet volume (MPV), plateletcrit (PCT), their potential usage in the diagnosis and determination of the clinical severity in dogs with hemorrhagic enteritis. Materials, Methods & Results: In this study, the case records of 29 dogs with hemorrhagic enteritis were evaluated and the records of 10 healthy dogs were used as controls. The animals of the study group were presented at the Ondokuz Mayis University, Veterinary Internal Medicine Clinic. The complete blood count (CBC), which includes the total WBC, RBC, hematocrit (HCT), hemoglobin concentration (Hgb), MCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), RDW, PLT, MPV, PCT, and PDW, was determined. Significant positive correlations between RDW and RBC, HCT, MCHC, PLT and PDW, and a negative correlation with MCV, were determined. PDW was positively correlated with the lymphocyte count, MCHC and RDW, and negatively correlated with PCT. PLT was negatively correlated with MCV and MPV and positively correlated with RBC and RDW. In addition, MPV was positively correlated with MCV and MCH, and negatively correlated with PLT. Furthermore, there were significant differences between the granulocyte, WBC, HCT, RDW and PDW values (P < 0.001) and monocyte count, Hgb and MCV (P < 0.05), of the study and control groups. [ ]
Assuntos
Animais , Cães , Contagem de Eritrócitos/veterinária , Contagem de Plaquetas/veterinária , Enterite/diagnóstico , Enterite/veterinária , Contagem de Células Sanguíneas/veterinária , Hemorragia , Padrões de ReferênciaRESUMO
Background: Respiratory disease negatively affects the physiological performance of racehorses. Inflammatory Airway Disease (IAD) is a typical respiratory disease that affects young horses. The pathogenesis of IAD remains incompletely defined but it is thought to be associated with the inhalation of irritants such as barn dust and air pollution. Although noninfectious agents are likely to be central to the development of IAD, infectious agents can be associated with the disease. The main objective of the present study was to determine the relationships between IAD and antioxidant capacity, ceruloplasmin levels and bacterial and fungal infection status, in racehorses. Materials, Methods & Results: In this study, 25 thoroughbred race horses with exercise intolerance and respiratory system symptoms were evaluated as the study group and 10 healthy horses were included in the control group. Clinical examinations, endoscopic evaluation and tracheal lavage were administered to all horses. Mucus accumulation in the trachea was scored and the horses having a mucus score of ≥ 3 were included the study group. Tracheal lavage fluids were investigated to determine the microbiological status of all animals. In addition, blood samples were collected and total oxidant capacity (TOC), total antioxidant capacity (TAC) and ceruloplasmin (Cp) levels were determined with a spectroscopic method. Exercise intolerance and various respiratory system symptoms such as coughing, nasal discharge and noisy breathing, were the common findings from horses in the study group. Fungal culture was negative and only Streptococcus equi subsp. zooepidemicus strain was isolated from 6 samples. No statistical difference was determined between the TOC, TAC and Cp levels of the groups (P > .05).[...]
Assuntos
Animais , Antioxidantes/análise , Cavalos , Ceruloplasmina/análise , Doenças Respiratórias/veterinária , Infecções Bacterianas/veterinária , Micoses/veterináriaRESUMO
Background: Respiratory disease negatively affects the physiological performance of racehorses. Inflammatory Airway Disease (IAD) is a typical respiratory disease that affects young horses. The pathogenesis of IAD remains incompletely defined but it is thought to be associated with the inhalation of irritants such as barn dust and air pollution. Although noninfectious agents are likely to be central to the development of IAD, infectious agents can be associated with the disease. The main objective of the present study was to determine the relationships between IAD and antioxidant capacity, ceruloplasmin levels and bacterial and fungal infection status, in racehorses. Materials, Methods & Results: In this study, 25 thoroughbred race horses with exercise intolerance and respiratory system symptoms were evaluated as the study group and 10 healthy horses were included in the control group. Clinical examinations, endoscopic evaluation and tracheal lavage were administered to all horses. Mucus accumulation in the trachea was scored and the horses having a mucus score of ≥ 3 were included the study group. Tracheal lavage fluids were investigated to determine the microbiological status of all animals. In addition, blood samples were collected and total oxidant capacity (TOC), total antioxidant capacity (TAC) and ceruloplasmin (Cp) levels were determined with a spectroscopic method. Exercise intolerance and various respiratory system symptoms such as coughing, nasal discharge and noisy breathing, were the common findings from horses in the study group. Fungal culture was negative and only Streptococcus equi subsp. zooepidemicus strain was isolated from 6 samples. No statistical difference was determined between the TOC, TAC and Cp levels of the groups (P > .05).[...](AU)
Assuntos
Animais , Ceruloplasmina/análise , Cavalos , Doenças Respiratórias/veterinária , Antioxidantes/análise , Infecções Bacterianas/veterinária , Micoses/veterináriaRESUMO
Background: Some blood parameters have diagnostic and prognostic importance for the infections in human medicine. However, there is insufficient research regarding the importance of blood parameters and their correlations in veterinary medicine. Increased blood cell distribution width (RDW) and platelet activity can link with the important inflammatory markers. The main objective of the present study was the evaluation of the relationship among some important blood parameters namely RDW, platelet count (PLT), platelet distribution width (PDW), mean platelet volume (MPV), plateletcrit (PCT), their potential usage in the diagnosis and determination of the clinical severity in dogs with hemorrhagic enteritis. Materials, Methods & Results: In this study, the case records of 29 dogs with hemorrhagic enteritis were evaluated and the records of 10 healthy dogs were used as controls. The animals of the study group were presented at the Ondokuz Mayis University, Veterinary Internal Medicine Clinic. The complete blood count (CBC), which includes the total WBC, RBC, hematocrit (HCT), hemoglobin concentration (Hgb), MCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), RDW, PLT, MPV, PCT, and PDW, was determined. Significant positive correlations between RDW and RBC, HCT, MCHC, PLT and PDW, and a negative correlation with MCV, were determined. PDW was positively correlated with the lymphocyte count, MCHC and RDW, and negatively correlated with PCT. PLT was negatively correlated with MCV and MPV and positively correlated with RBC and RDW. In addition, MPV was positively correlated with MCV and MCH, and negatively correlated with PLT. Furthermore, there were significant differences between the granulocyte, WBC, HCT, RDW and PDW values (P < 0.001) and monocyte count, Hgb and MCV (P < 0.05), of the study and control groups. [ ](AU)