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1.
Bioengineering (Basel) ; 11(7)2024 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-39061779

RESUMO

INTRODUCTION: Peripheral nerve injury (PNI) is increasingly prevalent and challenging to treat despite advances in microsurgical techniques. In this context, adipose tissue derivatives, such as adipose-derived stem cells, nanofat, and stromal vascular fraction have been gaining attention as potential allies in peripheral nerve regeneration. OBJECTIVES: This study aims to explore the use of adipose tissue derivatives in nerve regeneration following peripheral nerve transection in murine models. Thus, we assess and synthesize the key techniques and methods used for evaluating the obtained nerve regeneration to guide future experimental research and clinical interventions. METHODOLOGY: A systematic review was conducted in February 2024, adhering to the Cochrane and PRISMA 2020 guidelines, using the PubMed, SciELO, and LILACS databases. The focus was on experimental studies involving adipose tissue derivatives in nerve regeneration in animal models post-transection. Only experimental trials reporting nerve regeneration outcomes were included; studies lacking a comparator group or evaluation methods were excluded. RESULTS: Out of 273 studies initially identified from MEDLINE, 19 were selected for detailed analysis. The average study included 32.5 subjects, with about 10.2 subjects per intervention subgroup. The predominant model was the sciatic nerve injury with a 10 mm gap. The most common intervention involved unprocessed adipose-derived stem cells, utilized in 14 articles. CONCLUSIONS: This review underscores the significant potential of current methodologies in peripheral nerve regeneration, particularly highlighting the use of murine models and thorough evaluation techniques.

2.
Rev. bras. cir. plást ; 37(4): 474-484, out.dez.2022. ilus
Artigo em Inglês, Português | LILACS-Express | LILACS | ID: biblio-1413219

RESUMO

Introdução: As Ligas Acadêmicas de Cirurgia Plástica (LCP) são organizações estudantis que objetivam complementar a formação acadêmica em cirurgia plástica. Atuam por meio dos pilares de ensino, pesquisa e extensão que promovem o contato dos estudantes com a realidade social em que estão inseridos, permitindo-os entender as verdadeiras necessidades da população e atuar como agentes de transformação social. No entanto, a abordagem do tema na literatura ainda é incipiente. O presente trabalho objetiva descrever a atuação das LCP vinculadas à Associação Brasileira das Ligas de Cirurgia Plástica (ABLCP). Métodos: Tratou-se de um estudo transversal, descritivo, multicêntrico de abordagem qualiquantitativa, mediante a aplicação de um questionário de 19 perguntas construídas de modo a evitar os vieses demonstrados no Catálogo de Vieses em Questionários. Resultados: Foi observado que existem 78 LCPs e 1873 ligantes, presentes em 58 cidades ao longo de 20 estados, sendo a Região Sudeste com o maior número de ligas e ligantes, já a Região Norte apresenta a menor quantidade de ligas e alunos. Além do mais, foi visto que 78,2% das ligas são vinculadas à ABLCP e apresentam atividades nos três eixos (educação, pesquisa e extensão). Em geral, as ligas têm menos participação em pesquisa. Conclusão: A ABLCP objetiva melhorar a performance das ligas, inspecionar e estimular suas atividades, uma vez que as ligas possuem um papel importante na educação médica.


Introduction: The Academic Leagues are non-profit autonomous civil and scientific student entities, of indefinite duration, which brings together medical students and professors. The Brazilian Association of Plastic Surgery Leagues (ABLCP) is an organization linked to the Brazilian Society of Plastic Surgery (SBCP), considered its academic segment, thus establishing the proximity between Academic Leagues of Plastic Surgery (PSL) and SBCP. The present study aims to describe the profile of the associated leagues. Methods: This was a cross-sectional, descriptive, multicenter study with qualitative and quantitative approach through application of an online questionnaire with 19 questions. Duplicated or unfinished records were excluded. Results: It was observed that there are 78 PSLs and 1873 binders, present in 58 cities arranged in 20 federative units, being the Southeast region with the largest number of alloys and binders and the one with the smallest number was the North region. In addition, it was observed that 78.2% of the PSLs linked to the ABLCP presented activities in the three axes (Education, Research and Extension/Assistance) simultaneously. In general, the Leagues obtained less participation in research. Conclusions: ABLCPs performance in relation to LCPs has the objective of seeking alignment, inspection and stimulus for their activities, since alloys have an important role in medical education.

3.
Rev. para. med ; 28(1)jan.-mar. 2014. tab
Artigo em Português | LILACS-Express | LILACS | ID: lil-712230

RESUMO

Objetivo: Descrever o perfil clínico-epidemiológico dos pacientes diagnosticados com ISC; identificar eventuais fatores de risco; e avaliar sua relação com o escore de risco NNIS. Método: trata-se de um estudo descritivo e retrospectivo, que avaliou dados de 241 pacientes submetidos a procedimentos em cirurgia geral, em um hospital terciário, no período de janeiro a dezembro de 2012. Resultados: a taxa de incidência global de ISC foi de 8,7% (IC95%: 5,2 a 12,3%). Somente 38,1% dos diagnósticos se deram na internação hospitalar. A faixa etária com maior incidência foi a de 61 a 75 anos (17,7%). O sexo masculino apresentou maior taxa de ISC, ?10,4% contra 7,4%. As comorbidades mais prevalentes foram: a hipertensão arterial sistêmica (22%); o tabagismo (15,8%), obesidade (14,1%) e o diabetes (6,6%). Conclusão: das variáveis estudadas, comportaram-se como fator de risco: o tabagismo, a imunossupressão, o índice ASA e o potencial de contaminação do procedimento cirúrgico. E como fator protetor: a ausência de comorbidades. Por fim, o estudo demonstra que o diagnóstico pós- alta hospitalar é bastante representativo sobre a taxa global de ISC, e que existe uma real associação entre a ocorrência da ISC e o aumento da classificação do escore de risco NNIS


Objective: Describe the clinical and epidemiological opment of patients diagnosed with SSI; identify possible risk factors and to evaluate its relationship with the NNIS risk score. Method: was a descriptive and retrospective study that evaluated data from 241 patients undergoing general surgery in a tertiary hospital from January to December 2012. Results: the overall incidence rate of SSI was 8.7% (95% CI: 5.2 to 12.3%). Only 38.1% of diagnoses were given in the hospital. The age group with the highest incidence was 61-75 years (17.7%). Males had higher rates of SSI, 10.4% versus 7.4%. The most prevalent comorbidities were hypertension (22%), smoking (15.8%), obesity (14.1%) and diabetes (6.6%). Conclusion: of the variables studied, behaved as risk factors: smoking, immunosuppression, the ASA index and the potential contamination of the surgical procedure. And as a protective factor: the absence of comorbidities. Finally, the study demonstrated that the post-hospital discharge diagnosis is fairly representative of the overall rate of SSI, and that there is a real association between the occurrence of SSI and increased risk score classification of NNIS.

4.
Acta Cir Bras ; 28(6): 467-73, 2013 Jun.
Artigo em Inglês, Português | MEDLINE | ID: mdl-23743686

RESUMO

PURPOSE: To evaluate the scientific production from the surgical areas from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB), Brazil. METHODS: The scientific productions of professors in the last five years were classified according to the Qualis system of CAPES-Medicine III (http://qualis.capes.gov.br/webqualis/publico/pesquisaPublicaClassificacao.seam?conversationPropagation=begin) and it was computed the number of guidance of students scientific projects. RESULTS: Seventy-four professors were included, 31 with Master and 43 with PhD degrees. UFPA presented more publications (49% out of the total), which 32% of them in Journals B1 or higher. Otorhinolaryngology presented the greatest number of publications (29% out of the total); however, 98% of them in B3 or lower. Gastroenterological Surgery, which is responsible for 23% out of the total, had 57% of its publications in B1 or higher. The most frequent type of guidance was the one about scientific work of completion of undergraduate course (63%). Gynecology and Obstetrics presented the greatest number of student's guidance (35% out of the total) and Gastroenterological Surgery the largest number of Master's degree and PhD degree supervisions. CONCLUSIONS: The specialties Gynecology and Obstetrics and Gastroenterological Surgery from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB) presented the greatest number of professors with academic degrees. Gastroenterological Surgery presented the largest scientific productions at higher strata of WebQualis CAPES classification and also the largest number of Master and PhD directed.


Assuntos
Pesquisa Biomédica/estatística & dados numéricos , Docentes/estatística & dados numéricos , Cirurgia Geral/estatística & dados numéricos , Publicações Periódicas como Assunto/estatística & dados numéricos , Brasil , Humanos , Fator de Impacto de Revistas , Universidades/estatística & dados numéricos
5.
Acta cir. bras ; Acta cir. bras;28(6): 467-473, June 2013. tab
Artigo em Inglês | LILACS | ID: lil-675583

RESUMO

PURPOSE: To evaluate the scientific production from the surgical areas from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB), Brazil. METHODS: The scientific productions of professors in the last five years were classified according to the Qualis system of CAPES-Medicine III (http://qualis.capes.gov.br/webqualis/publico/pesquisaPublicaClassificacao.seam?conversationPropagation=begin) and it was computed the number of guidance of students scientific projects. RESULTS: Seventy-four professors were included, 31 with Master and 43 with PhD degrees. UFPA presented more publications (49% out of the total), which 32% of them in Journals B1 or higher. Otorhinolaryngology presented the greatest number of publications (29% out of the total); however, 98% of them in B3 or lower. Gastroenterological Surgery, which is responsible for 23% out of the total, had 57% of its publications in B1 or higher. The most frequent type of guidance was the one about scientific work of completion of undergraduate course (63%). Gynecology and Obstetrics presented the greatest number of student's guidance (35% out of the total) and Gastroenterological Surgery the largest number of Master's degree and PhD degree supervisions. CONCLUSIONS: The specialties Gynecology and Obstetrics and Gastroenterological Surgery from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB) presented the greatest number of professors with academic degrees. Gastroenterological Surgery presented the largest scientific productions at higher strata of WebQualis CAPES classification and also the largest number of Master and PhD directed.


Assuntos
Humanos , Pesquisa Biomédica/estatística & dados numéricos , Docentes/estatística & dados numéricos , Cirurgia Geral/estatística & dados numéricos , Publicações Periódicas como Assunto/estatística & dados numéricos , Brasil , Fator de Impacto de Revistas , Universidades/estatística & dados numéricos
6.
Acta cir. bras. ; 28(6): 467-473, 2013. tab
Artigo em Inglês | VETINDEX | ID: vti-8997

RESUMO

PURPOSE: To evaluate the scientific production from the surgical areas from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB), Brazil. METHODS: The scientific productions of professors in the last five years were classified according to the Qualis system of CAPES-Medicine III (http://qualis.capes.gov.br/webqualis/publico/pesquisaPublicaClassificacao.seam?conversationPropagation=begin) and it was computed the number of guidance of students scientific projects. RESULTS: Seventy-four professors were included, 31 with Master and 43 with PhD degrees. UFPA presented more publications (49% out of the total), which 32% of them in Journals B1 or higher. Otorhinolaryngology presented the greatest number of publications (29% out of the total); however, 98% of them in B3 or lower. Gastroenterological Surgery, which is responsible for 23% out of the total, had 57% of its publications in B1 or higher. The most frequent type of guidance was the one about scientific work of completion of undergraduate course (63%). Gynecology and Obstetrics presented the greatest number of student's guidance (35% out of the total) and Gastroenterological Surgery the largest number of Master's degree and PhD degree supervisions. CONCLUSIONS: The specialties Gynecology and Obstetrics and Gastroenterological Surgery from the State University of Para (UEPA), Federal Universities of Para (UFPA) and of Paraiba (UFPB) presented the greatest number of professors with academic degrees. Gastroenterological Surgery presented the largest scientific productions at higher strata of WebQualis CAPES classification and also the largest number of Master and PhD directed.(AU)


Assuntos
Humanos , Animais , Instituições Acadêmicas/estatística & dados numéricos , Disciplinas das Ciências Biológicas , Docentes/estatística & dados numéricos
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