RESUMO
The objective was to evaluate the association of an abnormal second trimester prenatal biochemical screening with the subsecuent development of pregnancy complications in women carrying chromosomally normal fetuses. A prospective study of 123 pregnant patients was performed. Specimens were assayed for alpha-fetoprotein, unconjugated estriol, free alpha hCG, and total hCG. The study included the evaluation of the mean and standard desviation as well as multiple of the median. Six women (4.6%) had positive results. The frequency of pregnancy complications in this group was 33.3%, while in the group with negative screening was 11.1%. As conclusion, positive four marker screening is associated with a adverse pregnancy evolution. However the usefulness of four marker screening for to predict pregnancy complications needs more investigations.
Assuntos
Estriol/análise , Subunidade alfa de Hormônios Glicoproteicos/análise , Complicações na Gravidez/diagnóstico , alfa-Fetoproteínas/análise , Adulto , Gonadotropina Coriônica/análise , Feminino , Humanos , Valor Preditivo dos Testes , Gravidez , Prognóstico , Estudos ProspectivosRESUMO
The purpose of this trial is to demonstrate that a women with high body mass index (BMI > or = 28) has greater bone mineral density (BMD) from that with lower BMI. We studied 922 healthy women who met the inclusion criteria. They were classified into four groups according to their BMI (> or = 28 and < 28) and age (> or = 35 and < 35 years). Bone mineral measurement was performed by dual-energy X-ray absorptiometry (DEXA) in the hip and at the lumbar region. BMD in overweight women older than 35 years was significantly higher in comparison with that of women with lower BMI, both in the hip and the lumbar spine. In overweight women younger than 35 years, we found greater BMD in the hip reaching statistical significance, but not at the lumbar spine. We conclude that obesity is associated with greater BMD (4% at the lumbar spine; 11% at the hip) probably due to both greater physical stress and higher estrogen levels.
Assuntos
Índice de Massa Corporal , Densidade Óssea , Calcificação Fisiológica , Obesidade/metabolismo , Adulto , Estrogênios/análise , Feminino , Articulação do Quadril/química , Humanos , Vértebras Lombares/química , México , Estudos de AmostragemRESUMO
Today, million of woman in the world lived enough to experience the menopause ant it's seculae. In the last few years the research of the events associated with this age has gained enormous attention. Hormonal replacement therapy has been shown to reduce the incidence of cardiovascular disease, osteoporosis and other complications in postmenopausal woman. In this paper we review the endocrinology of the menopause, benefits and risks of hormonal replacement therapy, Prescription choices, compliance and health care professional attitudes are too analysed.
Assuntos
Climatério/fisiologia , Terapia de Reposição de Estrogênios , Menopausa/fisiologia , Adulto , Doenças Cardiovasculares/prevenção & controle , Feminino , Humanos , Pessoa de Meia-Idade , Osteoporose/prevenção & controle , Pós-Menopausa , Pré-MenopausaRESUMO
The purpose of the present study is to determine the efficacy of an artificial insemination program with frozen donor sperm as an alternative therapy for male factor infertility. Twenty six women underwent 86 insemination cycles with frozen donor sperm. Clomiphene citrate or human menopausal gonadotropins were utilized for ovulation induction; human chorionic gonadotropins, 10,000 IU, was administered with one or more dominant follicles > or = 16 mm; intrauterine insemination was performed 36 hours after the injection. The pregnancy rate per cycle was 16.6%, and the cumulative pregnancy rate was 58.3%. It is concluded that intrauterine insemination with frozen donor sperm is a good alternative, instead of adoption, for male factor infertility with no available treatment.