RESUMO
Abstract Erythema ab igne is a condition characterized by skin changes due to chronic exposure to moderate temperature. We describe a female patient with continuous use of a laptop computer on exposed legs for 6 months and consequent development of reticulated hyperpigmentation at the area. Histopathological examination revealed epidermal atrophy, collagen fragmentation, and vacuolar changes in the basal layer, among other signs. We consider this case to be a modern cause of erythema ab igne.
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Microcomputadores , Hiperpigmentação/etiologia , Hiperpigmentação/patologia , Eritema/etiologia , Eritema/patologia , Temperatura Alta/efeitos adversos , Epiderme/patologiaRESUMO
Erythema ab igne is a condition characterized by skin changes due to chronic exposure to moderate temperature. We describe a female patient with continuous use of a laptop computer on exposed legs for 6 months and consequent development of reticulated hyperpigmentation at the area. Histopathological examination revealed epidermal atrophy, collagen fragmentation, and vacuolar changes in the basal layer, among other signs. We consider this case to be a modern cause of erythema ab igne.
Assuntos
Eritema/etiologia , Eritema/patologia , Temperatura Alta/efeitos adversos , Hiperpigmentação/etiologia , Hiperpigmentação/patologia , Microcomputadores , Epiderme/patologia , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
Photodynamic Therapy (PDT) with 5-aminolevulinic acid (ALA) is known to be limited for applications in tumours of large volume mainly due to the limited penetration of topical photosensitization. The results show that micro-holes created using a femtosecond laser before PDT significantly increased the depth of PDT effect in the healthy tissue. The combination of ultrashort laser ablation technique with PDT showed an important scientific breakthrough related to transportation and delivery of drugs into the deeper regions of the tissue.