RESUMO
Cutaneous larva migrans is a common infestation among travelers. Although the diagnosis may be suspected clinically, cases can show atypical presentations. We present the ultrasound features of 4 cases at 18 and 70 MHz. Small linear hyperechoic and hyper-refringent subepidermal and intrafollicular structures suggestive of fragments of larvae, hypoechoic dermal and hypodermal tunnels that match with dilatation of lymphatic ducts, and inflammatory dermal and hypodermal ultrasound signs can support the diagnosis. This work suggests that larvae can penetrate the cutaneous basement membrane through the ostia of the hair follicles and potentially disseminate through the dermal and hypodermal lymphatic network.
Assuntos
Larva Migrans/diagnóstico por imagem , Adulto , Feminino , Humanos , Ultrassonografia/métodosAssuntos
Adenoma/diagnóstico , Adenoma/cirurgia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/cirurgia , Eritema/diagnóstico , Eritema/cirurgia , Papiloma/diagnóstico , Papiloma/cirurgia , Adenoma/complicações , Idoso , Neoplasias da Mama/complicações , Diagnóstico Diferencial , Eritema/complicações , Feminino , Humanos , Mamilos/patologia , Mamilos/cirurgia , Papiloma/complicaçõesRESUMO
Abstract: Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. The lesions recurred once monthly at the same sites, mimicking a fixed drug eruption. Although the histopathology was compatible with fixed drug eruption, positive intradermal testing and symptomatic improvement after using oral contraceptive pills gave us a clue to the diagnosis.
Assuntos
Humanos , Feminino , Adulto , Progesterona/efeitos adversos , Doenças Autoimunes/diagnóstico , Toxidermias/diagnóstico , Dermatite/diagnósticoRESUMO
Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. The lesions recurred once monthly at the same sites, mimicking a fixed drug eruption. Although the histopathology was compatible with fixed drug eruption, positive intradermal testing and symptomatic improvement after using oral contraceptive pills gave us a clue to the diagnosis.
Assuntos
Doenças Autoimunes/diagnóstico , Dermatite/diagnóstico , Toxidermias/diagnóstico , Progesterona/efeitos adversos , Adulto , Feminino , HumanosRESUMO
Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
Assuntos
Porocarcinoma Écrino/patologia , Neoplasias Primárias Múltiplas/patologia , Poroma/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Idoso , Biópsia , Diagnóstico Diferencial , Porocarcinoma Écrino/diagnóstico , Humanos , Masculino , Neoplasias Primárias Múltiplas/diagnóstico , Poroma/diagnóstico , Neoplasias das Glândulas Sudoríparas/diagnósticoRESUMO
Abstract: Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
Assuntos
Humanos , Masculino , Idoso , Neoplasias das Glândulas Sudoríparas/patologia , Poroma/patologia , Porocarcinoma Écrino/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias das Glândulas Sudoríparas/diagnóstico , Biópsia , Diagnóstico Diferencial , Poroma/diagnóstico , Porocarcinoma Écrino/diagnóstico , Neoplasias Primárias Múltiplas/diagnósticoRESUMO
Finasteride is a 5-α reductase inhibitor that is widely used in the management of benign prostate hyperplasia and male pattern hair loss. It is well known that these agents improve the quality of life in men suffering from these conditions. However, they are associated with some transient and even permanent adverse effects. The aim of this article is to clarify the controversies about the safety of finasteride by analyzing the evidence available in the literature.
Assuntos
Humanos , Masculino , Finasterida/efeitos adversos , Inibidores de 5-alfa Redutase/efeitos adversos , Hiperplasia Prostática/tratamento farmacológico , Neoplasias da Próstata/prevenção & controle , Espermatogênese/efeitos dos fármacos , Glicemia/metabolismo , Finasterida/uso terapêutico , Alopecia/tratamento farmacológico , Metabolismo dos Lipídeos/efeitos dos fármacos , Inibidores de 5-alfa Redutase/uso terapêutico , Disfunção Erétil/induzido quimicamenteRESUMO
Finasteride is a 5-α reductase inhibitor that is widely used in the management of benign prostate hyperplasia and male pattern hair loss. It is well known that these agents improve the quality of life in men suffering from these conditions. However, they are associated with some transient and even permanent adverse effects. The aim of this article is to clarify the controversies about the safety of finasteride by analyzing the evidence available in the literature.