RESUMO
BACKGROUND: Individuals with cardiovascular exercise limitations present oxygen pulse morphology with early flattening (plateau) during the cardiopulmonary exercise test (CPET). Although this oxygen pulse response is well known in cardiac patients, these changes' prevalence and clinical relevance in asymptomatic individuals are not known. We aimed to quantify the proportion of asymptomatic adults with an early flattening of the oxygen pulse and investigate its association with classical cardiovascular risk factors. METHODS: We carried out a cross-sectional study with a sample of 824 adults aged between 18 and 80 years. We assessed anthropometry, body composition, and cardiovascular risk. In addition, we obtained cardiorespiratory and metabolic responses during a ramp protocol treadmill CPET. RESULTS: The prevalence of early flattening of the oxygen pulse was 36.8%. These participants were predominantly females, older, less educated, with a higher body mass and percentage of fat and a lower percentage of lean body mass. After a multinominal multiple logistic regression analysis, we identified female sex (odds ratio, 5.46: 95% confidence interval, 3.73-7.99), low education (2.24: 1.47-3.42), dyslipidemia (1.67: 1.14-2.45), smoking (1.64: 1.00-2.69), and physical inactivity (1.39: 1.02-1.96) as the leading independent predictors of the early flattening of oxygen pulse. CONCLUSION: The early flattening of oxygen pulse is common in asymptomatic adults and is highly determined by modifiable cardiovascular risk factors. These results suggest that identifying the early flattening of oxygen pulse may be helpful in the prevention of cardiovascular diseases.
Assuntos
Doenças Cardiovasculares , Teste de Esforço , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Cardiovasculares/diagnóstico , Doenças Cardiovasculares/epidemiologia , Estudos Transversais , Feminino , Fatores de Risco de Doenças Cardíacas , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio , Consumo de Oxigênio/fisiologia , Fatores de Risco , Adulto JovemRESUMO
Abstract Aim Evaluate and compare the proportion of PI and associated factors by IPAQ questionnaire, triaxial accelerometry and the combination of both. Adults aged ( 18 years were enrolled (n = 250). Methods We considered PI as < 600 MET-min/wk in the IPAQ total score, < 150 min/wk of moderate-to-vigorous physical activity in 7 days accelerometry, and the combination of both criteria. Clinical assessment, spirometry, cardiopulmonary exercise test, bioelectrical impedance, isokinetic dynamometry, postural balance, and six-minute walk test were also performed. For participants practicing aquatic, martial arts or cycling, only the IPAQ criterion was considered. Results Proportions of PI were significantly different among methods (IPAQ, 10%; accelerometry, 20%; combination, 25%). After multivariate logistic regressions, PI was determined by age, sex, educational level, risk factors for cardiovascular disease, lean body mass, cardiorespiratory fitness, and postural balance. Conclusion Thus, the combined method for determining PI and associated factors in adults showed great validity, indicating that questionnaires and accelerometers are complementary and should be utilized in combination in epidemiological studies.(AU)