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1.
Ginecol. obstet. Méx ; Ginecol. obstet. Méx;87(1): 60-66, ene. 2019. graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1154271

RESUMO

Resumen ANTECEDENTES: La enfermedad de Paget mamaria es una alteración poco frecuente, caracterizada por cambios en el área del pezón-areola, que puede asociarse con carcinoma de mama in situ o invasor. CASO CLÍNICO: Paciente de 69 años, con lesión mamaria de tres años de evolución, cambios en la coloración del pezón y descamación, acompañados de prurito, de aspecto eritematoso y escamoso en el área del pezón-areola izquierda, con retracción del pezón; se obtuvo una biopsia del área del pezón-areola. El estudio de patología reportó células neoplásicas grandes, con infiltración a la epidermis, aisladas o en pequeños grupos, con citoplasma claro, vacuolado, núcleo agrandado y nucléolo prominente, característico de la enfermedad de Paget mamaria. El estudio de inmunohistoquímica reportó positividad para CK7 y HER2, y negatividad para p53 a células neoplásicas, con lo que se estableció el diagnóstico definitivo de enfermedad de Paget mamaria. La mastografía no mostró alteraciones y la mastectomía reportó carcinoma intraductal. CONCLUSIÓN: El conocimiento de la enfermedad de Paget mamaria tiene importancia clínica, puesto que representa una afección poco frecuente, que debe considerarse en el diagnóstico diferencial de lesiones benignas del complejo areola-pezón.


Abstract BACKGROUND: The Paget´s disease mammary is an uncommon malignancy that presents with changes in the nipple-areolar region that may be associated with an underlying breast cancer. CLINICAL CASE: A 69-year-old patient with a breast lesion of three years of evolution, changes in nipple, characterized by coloration and scaling, pruritus, with an erythematous and scaly appearance in the nipple-areola left region, and nipple retraction. A biopsy of the nipple-areola was obtained. The Pathology service reported large neoplastic cells, with infiltration to the epidermis, isolated or in small groups, with clear cytoplasm, vacuolated, enlarged nucleus and prominent nucleolus, characteristic of Paget's disease mammary. The immunohistochemistry study reported positivity for CK7 and HER2, and negativity for p53 to neoplastic cells, which established the definitive diagnosis of Paget's disease of the breast. The mammography was normal and the mastectomy reported intraductal carcinoma. CONCLUSION: The knowledge of mammary Paget's disease is of clinical importance, since it represents a rare condition, which must be considered in the differential diagnosis of benign lesions of the areola-nipple complex.

2.
Ginecol Obstet Mex ; 79(6): 382-5, 2011 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-21966831

RESUMO

We report the case of a 44-year-old, who was resected of a vulvar tumor. The pathological report was leiomyoma with focal myxoid degeneration, which is an infrequent benign tumor.


Assuntos
Leiomioma/cirurgia , Neoplasias Vulvares/cirurgia , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Leiomioma/diagnóstico , Leiomioma/patologia , Neoplasias Vulvares/diagnóstico , Neoplasias Vulvares/patologia
3.
Ginecol Obstet Mex ; 75(10): 636-40, 2007 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-18800583

RESUMO

Verrucose epidermal nevus is a benign and congenital hyperplasia of the superficial epidermis and annexes. It expresses itself during the firs year of life, grows during childhood and in adolescence reaches its largest size. It can appear everywhere in skin surface. We present a case of late verrucose epidermal nevus with genital onset. Differential diagnosis was done with acuminated condylomas.


Assuntos
Hamartoma , Complicações na Gravidez , Dermatopatias , Adulto , Biópsia , Cauterização , Condiloma Acuminado/diagnóstico , Curetagem , Diagnóstico Diferencial , Feminino , Hamartoma/diagnóstico , Hamartoma/patologia , Hamartoma/cirurgia , Humanos , Gravidez , Complicações na Gravidez/diagnóstico , Complicações na Gravidez/patologia , Pele/patologia , Dermatopatias/diagnóstico , Dermatopatias/patologia , Dermatopatias/cirurgia
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