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Biomed Res Int ; 2019: 9641456, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31911931

RESUMO

The necessity to manufacture graft materials with superior biocompatibility capabilities and biodegradability characteristics for tissue regeneration has led to the production of extracellular matrix- (ECM-) based scaffolds. Among their advantages are better capacity to allow cell colonization, which enables its successful integration into the tissue surrounding the area to be repaired. In addition, it has been shown that some of these scaffolds have antimicrobial activity, preventing possible infections; therefore, it could be used as an alternative to control surgical infection and decrease the use of antimicrobial agents. The purpose of this review is to collect the existing information about antimicrobial activity of the ECM and their components.


Assuntos
Antibacterianos , Materiais Biocompatíveis , Matriz Extracelular , Engenharia Tecidual/métodos , Alicerces Teciduais , Animais , Bactérias/efeitos dos fármacos , Cães , Mucosa Intestinal/citologia , Ratos , Bexiga Urinária/citologia
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