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1.
Rev. cuba. med. trop ; 59(2)Mayo-ago. 2007.
Artigo em Espanhol | CUMED | ID: cum-34905

RESUMO

Se presentó el caso de un paciente con transplante renal, de 64 años, trabajador de una granja avícola, que sufrió una meningoencefalitis a los 6 meses de recibir tratamiento inmunosupresor. El diagnóstico rápido se realizó a partir de una muestra de líquido cefalorraquídeo mediante el empleo de partículas de látex para la detección de antígeno de Cryptococcus spp. Después se confirmó con el cultivo de la muestra clínica empleando agar-Sabouraud-cloranfenicol; la identificación bioquímica se realizó con el sistema API 20C AUX. Inmediatamente se inició el tratamiento con anfotericina B, con posterior cambio a fluconazol hasta negativizar los exámenes microbiológicos. Pasados 5 meses presentó una recaída, y se reinició el tratamiento específico. Se le dio seguimiento por consulta y presentó una evolución favorable hasta 2 años después del trasplante de órgano(AU)


This article presented the case of a 64 years-old renal transplant recipient, who was a poultry farm worker and had suffered meningoencephalitis six months after receiving immunosuppressive therapy. Rapid diagnosis was based on a cerebrospinal fluid sample analyzed with latex particles for Cryptococcus spp antigen detection. Culture of the clinical sample in agar-Sabouraund-chloramphenicol medium confirmed the initial diagnosis whereas biochemical identification was made with the API 20C AUX system. Amphotericin B treatment was immediately applied to the patient and later fluconazole until microbiological tests yielded negative results. After 5 months, the patient relapsed and restarted the specific treatment. He was followed up on outpatient service and two year after the organ transplantation, his recovery was favourable(AU)


Assuntos
Humanos , Masculino , Transplante de Rim , Imunossupressores/efeitos adversos , Meningoencefalite/diagnóstico , Meningoencefalite/terapia
2.
Rev. cuba. med. trop ; 59(2)mayo-ago. 2007.
Artigo em Espanhol | LILACS | ID: lil-489529

RESUMO

Se presentó el caso de un paciente con transplante renal, de 64 años, trabajador de una granja avícola, que sufrió una meningoencefalitis a los 6 meses de recibir tratamiento inmunosupresor. El diagnóstico rápido se realizó a partir de una muestra de líquido cefalorraquídeo mediante el empleo de partículas de látex para la detección de antígeno de Cryptococcus spp. Después se confirmó con el cultivo de la muestra clínica empleando agar-Sabouraud-cloranfenicol; la identificación bioquímica se realizó con el sistema API 20C AUX. Inmediatamente se inició el tratamiento con anfotericina B, con posterior cambio a fluconazol hasta negativizar los exámenes microbiológicos. Pasados 5 meses presentó una recaída, y se reinició el tratamiento específico. Se le dio seguimiento por consulta y presentó una evolución favorable hasta 2 años después del trasplante de órgano.


This article presented the case of a 64 years-old renal transplant recipient, who was a poultry farm worker and had suffered meningoencephalitis six months after receiving immunosuppressive therapy. Rapid diagnosis was based on a cerebrospinal fluid sample analyzed with latex particles for Cryptococcus spp antigen detection. Culture of the clinical sample in agar-Sabouraund-chloramphenicol medium confirmed the initial diagnosis whereas biochemical identification was made with the API 20C AUX system. Amphotericin B treatment was immediately applied to the patient and later fluconazole until microbiological tests yielded negative results. After 5 months, the patient relapsed and restarted the specific treatment. He was followed up on outpatient service and two year after the organ transplantation, his recovery was favourable.


Assuntos
Humanos , Masculino , Imunossupressores/efeitos adversos , Transplante de Rim , Meningoencefalite/diagnóstico , Meningoencefalite/terapia
3.
Rev Cubana Med Trop ; 59(2): 169-72, 2007.
Artigo em Espanhol | MEDLINE | ID: mdl-23427453

RESUMO

This article presented the case of a 64 years-old renal transplant recipient, who was a poultry farm worker and had suffered meningoencephalitis six months after receiving immunosuppressive therapy. Rapid diagnosis was based on a cerebrospinal fluid sample analyzed with latex particles for Cryptococcus spp antigen detection. Culture of the clinical sample in agar-Sabouraund-chloramphenicol medium confirmed the initial diagnosis whereas biochemical identification was made with the API 20C AUX system. Amphotericin B treatment was immediately applied to the patient and later fluconazole until microbiological tests yielded negative results. After 5 months, the patient relapsed and restarted the specific treatment. He was followed up on outpatient service and two year after the organ transplantation, his recovery was favourable.


Assuntos
Criação de Animais Domésticos , Transplante de Rim , Meningite Criptocócica/etiologia , Doenças Profissionais/etiologia , Infecções Oportunistas/etiologia , Anfotericina B/farmacologia , Anfotericina B/uso terapêutico , Animais , Antifúngicos/farmacologia , Antifúngicos/uso terapêutico , Cryptococcus neoformans/efeitos dos fármacos , Cryptococcus neoformans/isolamento & purificação , Reservatórios de Doenças , Fluconazol/farmacologia , Fluconazol/uso terapêutico , Humanos , Hospedeiro Imunocomprometido , Terapia de Imunossupressão/efeitos adversos , Masculino , Meningite Criptocócica/líquido cefalorraquidiano , Meningite Criptocócica/diagnóstico , Pessoa de Meia-Idade , Doenças Profissionais/líquido cefalorraquidiano , Doenças Profissionais/diagnóstico , Doenças Profissionais/microbiologia , Exposição Ocupacional , Infecções Oportunistas/líquido cefalorraquidiano , Infecções Oportunistas/diagnóstico , Infecções Oportunistas/microbiologia , Aves Domésticas/microbiologia , Recidiva
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