RESUMO

Because high-dose oral dexamethasone therapy has been reported to be effective for adults with idiopathic thrombocytopenic purpura, we assessed the short-term efficacy and toxicity of dexamethasone in seven children with chronic or refractory idiopathic thrombocytopenic purpura. Dexamethasone therapy was effective and well tolerated; further long-term studies are warranted.

Assuntos

Anti-Inflamatórios/uso terapêutico , Dexametasona/uso terapêutico , Púrpura Trombocitopênica/tratamento farmacológico , Adolescente , Anti-Inflamatórios/administração & dosagem , Criança , Pré-Escolar , Dexametasona/administração & dosagem , Dexametasona/efeitos adversos , Relação Dose-Resposta a Droga , Feminino , Humanos , Masculino , Contagem de Plaquetas