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Acta Gastroenterol Latinoam ; 36(4): 174-81, 2006 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-17225444

RESUMO

The goal of this population-based clinical, biochemical and ultrasonographic study was to assess the prevalence of liver diseases in Lara, a small rural community isolated in the mountain heights of Tucumán, a Province of Argentina with the highest reported rates of HAV infection in children. Inhabitants of Lara lack electricity, potable water and a sewer system. The study included 102 individuals representing 41% of the total population. Anti-HBc and anti-HCV were negative in all cases. No children showed clinical, biochemical or ecographic abnormalities. Among adults, 41% referred alcohol consumption and 12% blood transfusions. Only 3 adults (6%) had mildly elevated ALT. Ultrasound showed steatosis in 8 individuals (16%), gallstones in 7 (14%), parenchymal micro-calcifications in 5 (10%) and parasitic cysts in 4 (8%). Prevalence of HAV infection in Lara was 89% in adults and 35% in children, being significantly lower than that of children of medium/high (53%, p = 0.05) and low (74%, p = 0.0006) socioeconomic level from the city of Tucumán (control groups). These differences were more marked in children aged < 5 years (anti-HAV in 0%, 53% and 75% respectively). Serologic tests for echinoccocal disease were positive in 3/4 individuals with parasitic cysts, 2/5 with micro-calcifications and 17/85 (20%) with normal ultrasound, thus suggesting a high rate of false-positive results of the Elisa test utilized. This study showed that in Lara there is a high prevalence of steatosis, gallstones and equinoccocal disease in adults, absence of HBVand HCV infection and low exposure to HAV in children especially in those aged < 5 years.


Assuntos
Altitude , Hepatopatias/epidemiologia , Adulto , Argentina/epidemiologia , Criança , Pré-Escolar , Estudos Transversais , Equinococose Hepática/sangue , Equinococose Hepática/diagnóstico por imagem , Equinococose Hepática/epidemiologia , Fígado Gorduroso/sangue , Fígado Gorduroso/diagnóstico por imagem , Fígado Gorduroso/epidemiologia , Feminino , Hepatite A/sangue , Hepatite A/diagnóstico por imagem , Hepatite A/epidemiologia , Humanos , Lactente , Litíase/sangue , Litíase/diagnóstico por imagem , Litíase/epidemiologia , Hepatopatias/sangue , Hepatopatias/diagnóstico por imagem , Masculino , Prevalência , Fatores de Risco , Saúde da População Rural , Ultrassonografia
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