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BACKGROUND: The Osteoarthritis Knowledge Scale (OAKS) is a validated tool for assessing knowledge about hip and knee osteoarthritis (OA). However, to date, there has been no translation and adaptation of the OAKS for the Turkish population. OBJECTIVES: To translate and cross-culturally adapt the OAKS into Turkish and to assess its psychometric properties in the Turkish population with and without hip or knee OA. METHODS: The OAKS was translated following accepted guidelines. A validation study assessed internal consistency, test-retest reliability and measurement error. An exploratory factor analysis was conducted to assess the factor structure. RESULTS: A total of 278 participants (n = 70 with hip OA, n = 105 with knee OA, and n = 103 without OA) were included. Internal consistency was 0.72, 0.79 and 0.79 for participants with hip OA, knee OA, and no OA, respectively. The test-retest intraclass correlation coefficient was 0.72 (95% CI; 0.45-0.85), 0.89 (95% CI; 0.82-0.93) and 0.88 (95% CI; 0.79-0.93) for participants with hip OA, knee OA and no OA, respectively. It had three principal components accounting for 57.2% of the total variance. CONCLUSIONS: The Turkish version of the OAKS is a reliable and valid tool for measuring OA knowledge in the Turkish population, including those with and without hip and knee OA. Test-retest reliability was below acceptable levels in the population with hip OA only. Therefore, we recommend that the ICC be interpreted with caution when used in this population.
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Osteoartritis de la Cadera , Osteoartritis de la Rodilla , Psicometría , Traducciones , Humanos , Femenino , Masculino , Turquía , Persona de Mediana Edad , Osteoartritis de la Cadera/psicología , Anciano , Reproducibilidad de los Resultados , Conocimientos, Actitudes y Práctica en Salud , Encuestas y Cuestionarios/normas , Comparación TransculturalRESUMEN
Epilepsy is a frequent chronic and genetic brain disease. In diagnose of genetic and craniofacial disease, the face is one of the gold standard phenotypic features. This study was carried out to determine the angle and linear measurements of face region in Turkish healthy and epilepsy subjects, and to apply a feature selection method to identify the most important attributes that affect epilepsy decision. The retrospective and observational study was conducted with 120 subjects with epilepsy aged between 18 to 60 years (56 males; 64 females) and 60 healthy subjects aged between 18 and 55 years (29 males, 31 females). Pyramidal angle performed from 3 reference points, nasal bone length, the width of piriform aperture, nasofrontal angle, nasolabial angle, distance between glabella and nasion were measured on computed tomography. Also, we used supervised machine learning to learn classification models to detect epilepsy as our dataset has class label where 1 means epilepsy, 2 means healthy. The well-known classification model learning algorithms implemented in Weka (with version 3.8.6) machine learning toolkit were applied. All parameters excluding nasal bone length were higher in epilepsy patients than in healthy subjects. Also, there was a significant difference in nasal pyramidal angle nasal bone, nasal pyramidal angle nasal tip, piriform aperture, and nasal bone lengths between epilepsy and healthy subjects. However, age related changes for healthy subjects were no seen in healthy subjects. In epilepsy subjects there was a significant difference in 6 measurements all nasal pyramidal angles, piriform aperture width, nasofrontal angle, and nasolabial angle. Gender related changes were found in only nasal pyramidal angle nasal root and nasal bone of healthy subjects, in nasal pyramidal angle nasal bone, nasal bone length, nasofrontal angle of epilepsy subjects. We can say epilepsy may affect the some facial parameters and these, although anthropometric measurements are affected by age and gender parameters. Comprehensive knowledge of this region's normal references ranges is essential for planning, proper selection of silicone implants or osteotomy determining the limitations of the surgical field and minimizing the risk of complication and performing aesthetic facial surgery or rhinoplasty in epilepsy patients.
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Antropometría , Epilepsia , Nariz , Tomografía Computarizada por Rayos X , Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Estudios Retrospectivos , Epilepsia/diagnóstico por imagen , Adolescente , Adulto Joven , Tomografía Computarizada por Rayos X/métodos , Nariz/diagnóstico por imagen , Nariz/anatomía & histología , Antropometría/métodos , Cara/diagnóstico por imagen , Cara/anatomía & histología , Hueso Nasal/diagnóstico por imagen , TurquíaRESUMEN
OBJECTIVE: It is of critical importance to determine the factors that contribute to nurses' disaster preparedness. This study aimed to examine nurses' perceptions of disaster preparedness and the factors affecting it. METHODS: This descriptive study was conducted with 464 nurses working in the East Marmara region of Türkiye. The data were collected online using the "Personal Information Form," "The Scale of Perception of Disaster Preparedness on Nurses," and the "Adult Motivation Scale." Linear regression analysis was used to analyze the influencing factors. RESULTS: It was found that nurses possessed a high level of perceived disaster preparedness, influenced by individual disaster preparedness, status of receiving disaster-related training, willingness to respond in the case of a disaster, disaster plan awareness, experience with caring for disaster victims, extrinsic motivation, and general motivation. CONCLUSIONS: The results of the study offer evidence that can be implemented by managers and educators to better prepare nurses for disasters. Hospital administrators and policy makers should consider the factors affecting nurses' perception of disaster preparedness to develop solutions for such disasters.
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Enfermeras y Enfermeros , Humanos , Estudios Transversales , Adulto , Femenino , Masculino , Encuestas y Cuestionarios , Enfermeras y Enfermeros/psicología , Enfermeras y Enfermeros/estadística & datos numéricos , Turquía , Actitud del Personal de Salud , Persona de Mediana Edad , Percepción , Planificación en Desastres/métodos , Defensa Civil/métodos , Defensa Civil/estadística & datos numéricos , MotivaciónRESUMEN
Monitoring the land use/land cover (LU/LC) changes that have occurred with rapid population growth and urbanization since the Industrial Revolution is important for the optimal configuration of landscape patterns and ensuring the sustainability of ecological functions. Spatiotemporal dynamic pattern of LU/LC change using high-resolution land use data is an indicator to evaluate the landscape ecological risk through landscape pattern index analysis. In this study, the landscape ecological risk index (LERi) based on LU/LC change was calculated using remote sensing images of Landsat TM (Thematic Mapper) and OLI (Operational Land Imager) Rdata of a Gediz Mainstream Sub-basin in Turkiye between 1992 and 2022, and the spatial distribution regularity of LERi values was determined with spatial statistical analysis. According to the results, it was determined that the LERi values of the study area changed by 45% in 30 years. The highest change is in the very high-risk class, with an increase of 10.96%, and the least change occurred in the very low-risk class, with a decrease of 1.29%. According to the obtained statistical analysis results, it was determined that the global spatial autocorrelation values analyzed at different grain levels showed positive autocorrelation for both years and that the LERi values tended to have strong spatial clustering. As a result, it is emphasized that strict control measures should be taken for areas showing High-High (HH) autocorrelation type located in the southeast and north-southwest line of the study area at the local level, and ecological restoration applications should be given priority in these areas.
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Monitoreo del Ambiente , Análisis Espacio-Temporal , Monitoreo del Ambiente/métodos , Turquía , Conservación de los Recursos Naturales , Urbanización , Ecosistema , Medición de Riesgo , Imágenes Satelitales , Ecología , Tecnología de Sensores RemotosRESUMEN
We explore the ways in which residents of Neolithic Çatalhöyük in Anatolia differentiated themselves as well as the ways in which they did not. We integrate numerous data sets in order to assess patterns of inequality (A) across buildings with contemporaneous occupations, (B) between buildings that did or did not burn at abandonment, and (C) through time. We use Gini coefficients so as to maximize comparability with other studies of inequality in the ancient and modern worlds, discussing the underlying data and our results to clarify and enhance the value of the quantitative analyses. We evaluate whether or not trajectories of inequality align across data sets in order to determine how far success in one realm correlated with success in another. Our results indicate no unified trajectory of inequality through time. We perceive broadly similar access to staple foods, but not to goods less directly related to survival; relatively elevated income inequality during the middle portion of the site's occupation, plausibly deliberately tamped down; and no evidence for institutionalized or lasting economic or social inequality. These findings shed light on Neolithic social dynamics and also contribute to broader discussions of inequality and the social ramifications of early agropastoralism.
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Factores Socioeconómicos , Humanos , Renta , Turquía , Agricultura/historia , ArqueologíaRESUMEN
BACKGROUND: The Modified Early Obstetric Warning System (MEOWS) is a score-based or color-coded system that detects changes in physiological parameters and enables earlier diagnosis and care of worsening obstetric patients. The aim of this study is to evaluate the tool's performance and contribute to its use in Türkiye by translating MEOWS into Turkish. METHODS: This prospective and descriptive study, approved by the local ethics committee, included 350 obstetric in-patients who gave birth at Samsun Training and Research Hospital, Gynecology and Children's Hospital between April and August 2022. The study involved patients with a gestational week greater than 28 weeks and up to six weeks postpartum. RESULTS: The average age of the patients was 28.9±5.9 (18-40) years, with trigger values occurring in 34.6% (n=121) and morbidity occurring in 30.9% (n=108) of the cases. The most common trigger among the individual physiological indicators was high systolic blood pressure (28.3%). When the performance of MEOWS was evaluated, a statistically significant correlation was found between trigger and morbidity (Kappa=0.605; p<0.001). The sensitivity of MEOWS in estimating morbidity was 77.78% (95% confidence interval [CI]: 68.76-85.21%), specificity was 84.71% (95% CI: 79.55-89.00%), Positive Predictive Value (PPV) was 69.42% (95% CI: 62.40-75.64%), Negative Predictive Value (NPV) was 89.52% (95% CI: 85.67-92.43%), and accuracy was 82.57% (95% CI: 78.18-86.40%). CONCLUSION: MEOWS was found to be an effective screening tool for predicting morbidity in this study and performs well in Turkish with sufficient sensitivity, specificity, and accuracy. However, the inclusion of long-term results would provide a more comprehensive understanding of the effectiveness of MEOWS.
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Puntuación de Alerta Temprana , Humanos , Femenino , Embarazo , Turquía/epidemiología , Adulto , Estudios Prospectivos , Adolescente , Adulto Joven , Sensibilidad y Especificidad , Complicaciones del Embarazo/diagnóstico , Reproducibilidad de los Resultados , TraduccionesRESUMEN
BACKGROUND: This study aims to determine the prevalence of Attention Deficit Hyperactivity Disorder (ADHD) symptoms and the associated risk factors in children admitted to the Emergency Department (ED) due to traumas. METHODS: EChildren aged 3-16 years admitted to the ED for traumas were included in the study. The control group consisted of children aged between 3-16, who visited the pediatric ED for non-traumatic reasons. The Revised Conners Parent Rating Scale (CPRS-R) was administered to parents who agreed to participate following initial intervention and stabilization. Trauma patients were divided into two groups: those diagnosed with ADHD and those without ADHD. Risk factors likely to increase the identification of ADHD were assessed. RESULTS: The study included 917 children, with both groups showing similar characteristics regarding age, sex, demographic, and cultural factors. The most common reason for ED visits was extremity traumas, accounting for 296 (35.2%) cases. The majority of trauma patients (95.9%) were discharged from the ED after outpatient interventions. All subscale scores of the CPRS-R, except for the social problems subscale, were significantly higher in the study group compared to the control group. Factors that increased the risk of ADHD included admission with extremity traumas (p<0.001), previous ED admissions due to traumas (p<0.001), and having a family member previously diagnosed with ADHD (p<0.001). CONCLUSION: The prevalence of ADHD symptoms may be higher in children admitted to the ED due to traumas. Furthermore, extremity traumas, previous trauma-related ED-admissions, and a family history of ADHD increase the risk of ADHD.
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Trastorno por Déficit de Atención con Hiperactividad , Servicio de Urgencia en Hospital , Heridas y Lesiones , Humanos , Trastorno por Déficit de Atención con Hiperactividad/epidemiología , Niño , Femenino , Masculino , Servicio de Urgencia en Hospital/estadística & datos numéricos , Factores de Riesgo , Prevalencia , Adolescente , Preescolar , Heridas y Lesiones/epidemiología , Turquía/epidemiología , Estudios de Casos y ControlesRESUMEN
BACKGROUND: Firearm injuries (FI) remain a significant cause of morbidity and mortality globally. Antibiotic use, supported by guideline recommendations for preventing post-injury infections in FI cases, encounters uncertainties regarding the selection of anti-microbial agents and associated outcomes. This study aimed to investigate the relationship between Injury Severity Scores (ISS) for FI cases presented to the emergency department. METHODS: We empirically revised antimicrobial treatment protocols based on culture results and mortality rates. In the study, 164 firearm injury cases, admitted to the emergency department in 2022 and subsequently hospitalized in clinics and intensive care units (ICU), were evaluated. Cases included in the study were categorized into four groups based on ISS: mild, moderate, severe, and profound injury severity. The study compared the timing of hospital presentation following the injury, hospital length of stay, tissue or blood culture positivity, empirical treatment administered, antimicrobial revision based on culture results, need for ICU admission, mortality status, and ISS among the cases. Data were analyzed using IBM SPSS Statistics 22.0 (SPSS Inc., Chicago, IL). Variables in trauma patients were compared among various groups using Pearson Chi-Square tests. Binary logistic regression tests were performed to identify independent risk factors. A significance level of p<0.05 was considered statistically significant. RESULTS: The study included 164 patients, all of whom were male. The mean age was calculated as 28.9±4.51 years. The average hospital length of stay was 25.54±21.81 days. Eighty-three patients (50.6%) required intensive care. Tissue cultures were obtained from 79 patients (48%). Bacterial growth was observed in 45 of these 79 patients (57%). The appropriate empirical antibiotic treatment rate, assessed among patients who received empirical treatment followed by culture-based antibiotic sensitivity testing, was 48.9%. It was observed that empirical antibiotic regimens were appropriate in 80% of cases in the mild group and 16.7% in the profound severe group (p=0.005). Our study compared the relationship between hospitalization duration and ISS groups. It was observed that hospitalization duration was significantly shorter in the mild group compared to the other groups (p=0.003, p=0.000, p=0.000). It was also observed that the need for ICU admission was higher in groups with higher ISS, indicating a correlation between higher ISS and increased ICU requirements (p=0.000). CONCLUSION: In conclusion, for cases of firearm injuries, we believe empirical antimicrobial therapy should be initiated with narrow-spectrum agents such as beta-lactam + beta-lactamase inhibitor or third-generation cephalosporin + nitroimidazole in the mild group, considering the lack of Pseudomonal activity.
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Servicio de Urgencia en Hospital , Hospitalización , Heridas por Arma de Fuego , Humanos , Masculino , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Adulto , Hospitalización/estadística & datos numéricos , Persona de Mediana Edad , Puntaje de Gravedad del Traumatismo , Antibacterianos/uso terapéutico , Antibacterianos/administración & dosificación , Tiempo de Internación/estadística & datos numéricos , Estudios Retrospectivos , Adulto Joven , Antiinfecciosos/uso terapéutico , Adolescente , Turquía/epidemiologíaRESUMEN
BACKGROUND: Maxillofacial injuries, due to their diverse etiological causes, are often considered a component of multi-trauma and constitute a significant portion of trauma. This study aims to elucidate the incidence of maxillofacial traumas, particularly among military personnel, various clinical courses, and characteristics, thereby contributing to the literature. METHODS: Forensic reports, primarily related to military personnel and organized between 2011 and 2016 at the Forensic Medicine Department of Gülhane Medical Faculty, Health Sciences University, were retrospectively examined. The study involved a detailed analysis of cases with maxillofacial injuries resulting from trauma, focusing on aspects such as age, gender, the origin of the trauma, degree of injury, the presence of bone and dental fractures, and the occurrence of psychiatric disorders as a result of the trauma. RESULTS: This study demonstrated that maxillofacial traumas predominantly occurred in young male individuals, particularly among military personnel. The most common etiological factor identified was interpersonal violence. The majority of injuries were soft tissue damages, with the nasal bone being the most frequently fractured area. Injuries to the head and upper extremities were also detected in some of the cases, showing that multiple injuries are common in such cases. Post-traumatic psychological disorders developed in some cases, with anxiety disorders being the most commonly observed. CONCLUSION: It has been determined that maxillofacial injuries can affect multiple body regions, necessitating a multidisciplinary approach. This study underscores the importance of developing comprehensive strategies and policies for understanding and managing maxillofacial traumas, providing a fundamental reference for future studies in this field.
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Traumatismos Maxilofaciales , Humanos , Traumatismos Maxilofaciales/epidemiología , Traumatismos Maxilofaciales/etiología , Estudios Retrospectivos , Masculino , Femenino , Adulto , Adulto Joven , Persona de Mediana Edad , Adolescente , Personal Militar/estadística & datos numéricos , Turquía/epidemiología , Violencia/estadística & datos numéricos , Medicina Legal , AncianoRESUMEN
BACKGROUND: This study aimed to evaluate the approaches of pediatric surgeons and pediatric urologists in Türkiye regarding the diagnosis and treatment of testicular torsion (TT) and their adherence to the European Association of Urology (EAU) pediatric urology guideline. METHODS: A survey consisting of 19 questions, accompanied by an annotation describing the objective of the study, was emailed to pediatric surgeons and pediatric urologists in June and July 2023. RESULTS: Of the 95 respondents, 62.1% had over 10 years of experience, and 48.4% treated more than five cases of TT annually. Of the participants, 87.4% stated that scrotal Doppler ultrasonography (US) was always used, and 12.6% stated that US was used in cases of doubtful diagnosis. Concerning treatment, 14.7% reported performing manual detorsion, 70.5% never did, and 14.7% did so only if the operating room was unavailable soon. A total of 92.6% of participants opted for emergency surgery. Among participants who perform manual detorsion, 71.4% perform surgery within 24 hours after successful manual detorsion. Regarding fixation of the contralateral testicle, 14.7% never performed it, and 27.4% did so only when they performed an orchiectomy on the torsion testicle. CONCLUSION: While most participants follow EAU pediatric urology guidelines by performing emergency surgery, the rate of manual detorsion is low. Few participants stated that emergency surgery may not be performed after manual detorsion. While all of the participants performed fixation of the torsion testicle in accordance with the guidelines, the same adherence was not observed in the contralateral testicle.
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Torsión del Cordón Espermático , Torsión del Cordón Espermático/cirugía , Torsión del Cordón Espermático/diagnóstico , Torsión del Cordón Espermático/terapia , Torsión del Cordón Espermático/diagnóstico por imagen , Humanos , Masculino , Turquía , Encuestas y Cuestionarios , Pautas de la Práctica en Medicina/estadística & datos numéricos , Niño , Urólogos/estadística & datos numéricos , Cirujanos , Pediatría , Adhesión a Directriz/estadística & datos numéricosAsunto(s)
Identidad de Género , Psiquiatría , Humanos , Femenino , Psiquiatría/ética , Conducta Sexual , Masculino , Códigos de Ética , Ética Profesional , TurquíaRESUMEN
OBJECTIVE: This study aims to assess the efficacy and safety of tricuspid valve (TV) transcatheter edge-to-edge repair (TEER) procedures using the MitraClip or TriClip device in high-risk patients with severe secondary tricuspid regurgitation (TR) and provide Turkish-specific data on procedural outcomes and clinical follow-up. METHODS: This study enrolled 42 high-risk patients with severe secondary TR who underwent transcatheter edge-to-edge repair using either the MitraClip or TriClip device. Patient selection criteria included severe TR, high surgical risk (EuroScore ≥ 8 and Tricuspid Regurgitation Impact Severity Score (TRI-SCORE) ≥ 6), symptomatic despite medical therapy, and anatomical suitability for TriClip. Patients underwent rigorous evaluation by a specialized cardiac team before the procedure, including 2D/3D transesophageal echocardiography to assess eligibility. RESULTS: The study achieved a 100% procedural success rate, defined as successful implantation and at least one-degree reduction in TR severity. Post-procedure assessments revealed that 88.1% of patients had mild to moderate TR, indicating significant improvement, while only 11.9% retained severe TR. During the median follow-up of 11.5 months, rehospitalization occurred in 23.8% of patients, and mortality was observed in 7.1% of patients, demonstrating a favorable safety profile. Comparative analysis between TriClip and MitraClip devices showed similar efficacy and safety outcomes, with no significant differences in procedural durations or complication rates. CONCLUSION: The study demonstrates the effectiveness and safety of TV TEER using TriClip or MitraClip devices in managing severe secondary TR in high-risk patients. Procedure success, improved TR severity, and favorable clinical outcomes were observed, supporting the role of transcatheter techniques in TR management.
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Cateterismo Cardíaco , Insuficiencia de la Válvula Tricúspide , Humanos , Insuficiencia de la Válvula Tricúspide/cirugía , Insuficiencia de la Válvula Tricúspide/diagnóstico por imagen , Masculino , Femenino , Anciano , Resultado del Tratamiento , Cateterismo Cardíaco/métodos , Turquía , Válvula Tricúspide/cirugía , Válvula Tricúspide/diagnóstico por imagen , Ecocardiografía Transesofágica , Persona de Mediana Edad , Anciano de 80 o más Años , Índice de Severidad de la Enfermedad , Implantación de Prótesis de Válvulas Cardíacas/métodosRESUMEN
In this study, spatiotemporal analysis of forest fires in Turkiye was undertaken, with a specific focus on the large-scale atmospheric systems responsible for causing these fires. For this purpose, long-term variations in forest fires were classified based on the occurrence types (i.e. natural/lightning, negligence/inattention, arson, accident, unknown). The role of large-scale atmospheric circulations causing natural originated forest fires was investigated using NCEP/NCAR Reanalysis sea level pressure, and surface wind products for the selected episodes. According to the main results, Mediterranean (MeR), Aegean (AR), and Marmara (MR) regions of Turkiye are highly susceptible to forest fires. Statistically significant number of forest fires in the MeR and MR regions are associated with global warming trend of the Eastern Mediterranean Basin. In monthly distribution, forest fires frequently occur in the MeR part of Turkiye during September, August, and June months, respectively, and heat waves are responsible for forest fires in 2021. As a consequence of the extending summer Asiatic monsoon to the inner parts of Turkiye and the location of Azores surface high over Balkan Peninsula result in atmospheric blocking and associated calm weather conditions in the MeR (e.g. Mugla and Antalya provinces). When this blocking continues for a long time, southerly winds on the back slopes of the Taurus Mountains create a foehn effect, calm weather conditions and lack of moisture in the soil of Antalya and Mugla settlements trigger the formation of forest fires.
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Monitoreo del Ambiente , Bosques , Análisis Espacio-Temporal , Incendios Forestales , Turquía , Atmósfera/química , Incendios , Tiempo (Meteorología)RESUMEN
PURPOSE: Immunodysregulation, Polyendocrinopathy, Enteropathy, and X-linked syndrome (IPEX), caused by pathogenic FOXP3 variants, is a rare autoimmune disorder with diverse clinical features, including early-onset diabetes, eczema, and enteropathy. Atypical cases show milder symptoms and unique signs, requiring different treatments. Therefore, there are ambiguities in the accurate diagnosis and management of IPEX. We sought to present clinical, genetic, and immunological assessments of 12 IPEX patients with long-term follow-up to facilitate the diagnosis and management of the disease. METHODS: Clinical findings and treatment options of the patients were collected over time. Lymphocyte subpopulations, protein expressions, regulatory T (Treg) and circulating T follicular helper (cTFH) cells, and T-cell proliferation were analyzed. RESULTS: Predominant presentations included autoimmunity (91.6%), failure to thrive (66.7%), and eczema (58.3%). There were four classical and eight atypical IPEX individuals. Allergic manifestations were more common in atypical patients. Notably, chronic diarrhea demonstrated heightened severity compared to other manifestations. Four patients (33.3%) demonstrated eosinophilia, and nine (75%) showed high serum IgE levels. Most patients exhibited normal percentages of Treg cells with reduced CD25, FOXP3, and CTLA-4 expressions, corrected after hematopoietic stem cell transplantation (HSCT). Compared to healthy controls, the TH2-like skewing accompanied by reduced TH17-like responses was observed in cTFH and Treg cells of patients. Overall, nine patients (75%) received immunosuppressants (ISs), and six (50%) underwent HSCT, which was the only treatment revealing sustained control. Sirolimus was used in six patients and showed better control than other ISs. CONCLUSIONS: The first cohort from Turkey with long-term follow-up results, comparing typical and atypical cases, provides insights into the outcomes of different therapeutic modalities and T- cell subtype changes in IPEX syndrome.
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Factores de Transcripción Forkhead , Enfermedades Genéticas Ligadas al Cromosoma X , Linfocitos T Reguladores , Humanos , Turquía , Masculino , Preescolar , Factores de Transcripción Forkhead/genética , Factores de Transcripción Forkhead/metabolismo , Enfermedades Genéticas Ligadas al Cromosoma X/diagnóstico , Enfermedades Genéticas Ligadas al Cromosoma X/genética , Enfermedades Genéticas Ligadas al Cromosoma X/inmunología , Enfermedades Genéticas Ligadas al Cromosoma X/terapia , Linfocitos T Reguladores/inmunología , Lactante , Femenino , Niño , Diabetes Mellitus Tipo 1/inmunología , Diabetes Mellitus Tipo 1/diagnóstico , Diabetes Mellitus Tipo 1/genética , Diabetes Mellitus Tipo 1/congénito , Enfermedades del Sistema Inmune/diagnóstico , Enfermedades del Sistema Inmune/genética , Enfermedades del Sistema Inmune/terapia , Enfermedades del Sistema Inmune/congénito , Autoinmunidad , Adolescente , DiarreaRESUMEN
Objectives: To measure the effect of geriatric oral health education on the attitude of dentistry students towards the elderly. METHODS: The interventional study was conducted in December 2022 at Sivas, and comprised students of the Faculty of Dentistry, Sivas Cumhuriyet University, Turkiye in their 4th and 5th academic year. A 20-hour training course was delivered over 3 days by faculty members. Baseline and post-intervention difference was assessed using the Kogan's Attitudes Towards Old People Scale. Data was analysed using SPSS 22. RESULTS: Of the 30 students, 18(60%) were females and 12(40%) were males. The overall mean age was 22.93±1.63 years. Besides, 18(60%) students belonged to 5th year and 12(40%) to the 4th year. The mean Kogan Elderly Attitude Scale score at baseline was 184.13±25.55, while post-intervention it was 195.36±22.36. (p<0.05). CONCLUSIONS: Relevant training was found to have a significant impact on the attitude of dentistry students towards the elderly.
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Actitud del Personal de Salud , Educación en Odontología , Estudiantes de Odontología , Humanos , Estudiantes de Odontología/psicología , Estudiantes de Odontología/estadística & datos numéricos , Femenino , Masculino , Educación en Odontología/métodos , Adulto Joven , Odontología Geriátrica/educación , Turquía , Salud Bucal/educación , AncianoRESUMEN
Objectives: To analyse the phenomenon of "giving birth" on the basis of the lived experiences of women and midwives. METHODS: The qualitative study was conducted in the delivery room of a mother-friendly hospital in western Turkey from March 1 to December 30, 2019, and comprised primiparous women aged 18-35 years having a spontaneous vaginal birth, and midwives who delivered the babies. Data was collected through indepth interviews that were audiorecorded. Additionally, women's written birth stories and researcher's observation regarding the participants were used. Data was subjected to content analysis using NVIVO 12 Pro software. RESULTS: Of the 28 subjects 15(53.6%) were lay women with mean age 24.2±3.87 years (range: 18-30 years), and 13(46.4%) were midwives with mean age 42.61±4.50 years (range: 37-50 years). The most referred conceptual themes in Kolcaba's Theory of Comfort were "enhanced comfort", "mother-friendly hospital policy", and "midwives' comforting interventions." Under the theme of "Increasing Comfort", women cared about psychological and environmental comfort. Women had the most psychospiritual comfort and environmental comfort as well as physical and sociocultural comfort. Women cared about psychological and environmental comfort that facilitated birth. CONCLUSIONS: The mother-friendly hospital policy increased and contributed to the support and comfort provided to women. Kolcaba's Comfort Theory was an appropriate and working theory for birth and midwifery care, indicating that women's comfort should be ensured in the psychospiritual, environmental, physical and sociocultural contexts.
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Partería , Madres , Parto , Investigación Cualitativa , Humanos , Femenino , Adulto , Embarazo , Adulto Joven , Turquía , Madres/psicología , Parto/psicología , Adolescente , Persona de Mediana Edad , Parto Obstétrico/psicologíaRESUMEN
AIM: This study was conducted to examine the mediating role of psychological resilience in the effect of strength of religious faith on coping with stress in people with type 2 diabetes. DESIGN: This study has a cross-sectional descriptive-analytical study. METHODS: It was conducted with 184 people with type 2 diabetes who were admitted to a family health centre in Erzurum, the east of Turkey. The data were collected by using the 'Santa Clara Strength of Religious Faith Questionnaire', 'Brief Resilience Scale (BRS)' and 'Scale of Ways of Coping With Stress (SWCS)'. The study was reported by following the STROBE recommendations. Structural equation modelling and bootstrapping method were used to analyse the data. This study was reported following the STROBE recommendations. RESULTS: In the study, according to the model, the direct effect of strength of religious faith on SWCS (ß = 0.564; p < 0.01) and BRS (ß = 0.545; p < 0.01) was moderate, positive and significant. In addition, the effect of resilience on coping with stress (ß = 0.320; p < 0.01) was also found to be moderate, positive and significant. The total effect of strength of religious faith on coping with stress mediated by resilience (ß = 0.738; p < 0.01) was found to be highly positive and significant. The model explains 61.7% of the variance in coping with stress. Fit index values according to the model were found as χ2 = 2368.02, df: 980, χ2/df 2.368, RMSEA 0.088, CFI 0.773, TLI 0.760 and SRMR 0.083. It was found that strength of religious faith had a positive effect on coping with stress in people with type-2 diabetes, and this effect was strengthened by the mediating role of psychological resilience. PATIENT OR PUBLIC CONTRIBUTION: This study shows the effect of religious belief and psychological resilience in increasing the coping skills of people with type-2 diabetes. Therefore, taking religious beliefs and spirituality into consideration in nursing care may increase patients' coping skills.
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Adaptación Psicológica , Diabetes Mellitus Tipo 2 , Resiliencia Psicológica , Estrés Psicológico , Humanos , Diabetes Mellitus Tipo 2/psicología , Masculino , Femenino , Estudios Transversales , Persona de Mediana Edad , Estrés Psicológico/psicología , Turquía , Encuestas y Cuestionarios , Adulto , Anciano , ReligiónRESUMEN
Background: Plant-derived drugs are often preferred over synthetic drugs because of their superior safety profiles. Phenolic compounds and flavonoids-major plant components-possess antioxidant properties. Limited research has been conducted on the bioactive compounds and biochemical properties of Bellevalia pseudolongipes (Asparagaceae), an important pharmacological species endemic to Turkey. Therefore, the chemical composition and antioxidant properties of B. pseudolongipes were investigated in this study. Methods: The chemical composition of B. pseudolongipes was analyzed using liquid chromatography-high-resolution mass spectrometry, and radical scavenging and antioxidant activities were evaluated using DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) tests. Results: Thirty-eight compounds were identified, including trans-cinnamic acid, caffeic acid, vitexin, schaftoside, orientin, and narirutin. B. pseudolongipes showed high antioxidant activity in antioxidant activity tests. Conclusion: These findings provide novel insights into the potential utility of B. pseudolongipes in the pharmaceutical, food, and cosmetics industries, highlighted by its significant antioxidant capacity.
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Antioxidantes , Espectrometría de Masas , Fitoquímicos , Extractos Vegetales , Antioxidantes/farmacología , Antioxidantes/química , Antioxidantes/análisis , Extractos Vegetales/química , Extractos Vegetales/farmacología , Fitoquímicos/química , Fitoquímicos/análisis , Fitoquímicos/farmacología , Espectrometría de Masas/métodos , Cromatografía Liquida/métodos , Flavonoides/análisis , Flavonoides/química , Turquía , Fenoles/análisis , Fenoles/química , Ácidos Sulfónicos/química , Ácidos Sulfónicos/antagonistas & inhibidores , Compuestos de Bifenilo/química , BenzotiazolesRESUMEN
Current data on fosfomycin usage in children are limited. We present data on the clinical use of intravenous (IV) fosfomycin in children. Hospitalized patients who received ≥3 days of IV fosfomycin between April 2021 and March 2023 were analyzed retrospectively. Forty-three episodes of infection in 39 patients were evaluated. The mean age of the patients was 5.35 (10 days to 17.5 years) years, and 54% were male. Infections were hospital-acquired in 79% of the episodes. Indications for fosfomycin were urinary tract infection (35%), bacteremia (32.6%), catheter-related bloodstream infection (16.3%), soft tissue infection (4.7%), sepsis (4.7%), surgical site infection (2.3%), burn infection (2.3%), and pneumonia (2.3%). Klebsiella pneumoniae was identified in 46.5% of the episodes, and a pan-drug or extensive drug resistance was detected in 75% of them. Carbapenem was used before fosfomycin at significantly higher rates in K. pneumoniae episodes (P = .006). Most (88.5%) patients received fosfomycin as a combination therapy. Culture negativity was achieved in 80% of episodes within a median treatment period of 3 (2-22) days, which was significantly shorter in K. pneumoniae episodes (P < .001). Treatment-related side effects were seen in 9.3% of the episodes. Side effects were significant after 3 weeks of treatment (P = .013). The unresponsivity rate to fosfomycin was 23.3%. Nine (21%) of the patients who were followed up in the intensive care units mainly died because of sepsis (56%). IV fosfomycin is an effective agent in treating severe pediatric infections caused by resistant microorganisms. Fosfomycin can be used in various indications and is generally safe for children.
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Administración Intravenosa , Antibacterianos , Bacteriemia , Fosfomicina , Humanos , Fosfomicina/administración & dosificación , Fosfomicina/uso terapéutico , Masculino , Femenino , Antibacterianos/administración & dosificación , Antibacterianos/uso terapéutico , Niño , Estudios Retrospectivos , Turquía , Lactante , Adolescente , Preescolar , Resultado del Tratamiento , Bacteriemia/tratamiento farmacológico , Recién Nacido , Klebsiella pneumoniae/efectos de los fármacos , Klebsiella pneumoniae/aislamiento & purificación , Infección Hospitalaria/tratamiento farmacológico , Sepsis/tratamiento farmacológico , Infecciones Urinarias/tratamiento farmacológico , Infecciones por Klebsiella/tratamiento farmacológicoRESUMEN
OBJECTIVE: This subgroup analysis of the MORCOR-TURK (Mortality and Morbidity in Coronary Care Units in Türkiye) trial aimed to determine the short-term prognosis, mortality rates, and predictors for elderly patients followed in coronary care units (CCUs) in Türkiye. METHODS: The MORCOR-TURK trial is a national, non-interventional, multicenter observational study conducted in Türkiye (ClinicalTrials.gov number NCT05296694). The study population includes CCU patients from 50 centers selected from all regions of Türkiye (between September 1 and 30, 2022 prospectively). In the subgroup analysis, patients were divided into two groups: Group 1 (ages 65 to < 75 years, n = 923 patients) and Group 2 (ages ≥ 75 years, n = 713 patients). At the end of the analysis, short-term prognosis, mortality rates, and predictors were documented. RESULTS: The mean age of Group 1 was 69 (67-72) years, and Group 2 was 80 (77-84) years. Chest pain was the most common reason for admission (968 patients [59.16%]), and acute coronary syndrome was the most common reason for hospitalization in the CCU (1,053 patients [64%]). Atrial fibrillation (AF) was the most common arrhythmia (356 patients [21.76%]). The mortality rate was 6.11% in elderly patients (4.23% in Group 1 and 8.56% in Group 2). The multivariate regression analysis showed that age (P = 0.046, P = 0.003), chronic kidney disease (P = 0.011, P = 0.045), and ventricular tachycardia/ventricular fibrillation (VT/VF) during hospitalization (P < 0.001) were the main factors that increased mortality in both groups. Other independent mortality risk factors were smoking for Group 1 and aortic stenosis for Group 2. CONCLUSION: This study represents the most comprehensive assessment of the short-term prognosis for elderly patients admitted to CCUs in Türkiye. It showed that coronary artery disease was the most common reason for admission and age over 75 and chronic kidney disease were the main determinants of mortality.