RESUMEN
Solitary fibrous tumours of the pleura (SFTPs) are rare mesenchymal neoplasms usually originating from the visceral pleura, but they have been reported in many other sites. To the best of our knowledge, this report describes the first known case of synchronous SFTP in the left visceral pleura and brain. The SFTP of the brain was resected via craniotomy, whereas the SFTP of the pleura, widely compressing and displacing the left lower lung lobe, was resected via left thoracotomy.
Asunto(s)
Neoplasias Encefálicas/secundario , Tumor Fibroso Solitario Pleural/secundario , Anciano , Biomarcadores de Tumor/análisis , Neoplasias Encefálicas/química , Neoplasias Encefálicas/cirugía , Irradiación Craneana , Craneotomía , Humanos , Imagen por Resonancia Magnética , Masculino , Necrosis , Radioterapia Adyuvante , Tumor Fibroso Solitario Pleural/química , Tumor Fibroso Solitario Pleural/cirugía , Toracotomía , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
Solitary fibrous tumor (SFT) is a rare spindle cell tumor of mesenchymal origin that usually arises from pleura or pericardium but can also arise from many extraserosal sites. Although more than 50 cases of primary SFT of the orbit have been reported, there are no reports to date of a malignant nonophthalmic SFT metastasizing in the orbital soft tissues (although sphenoid wing bony involvement has been reported). The authors report here the first case of a patient with intraorbital metastasis of a CD34-positive malignant SFT. The patient was a 57-year-old man with a history of malignant pleural SFT and a prior kidney metastasis. He presented with the rapid appearance of proptosis and massive conjunctival chemosis preventing eyelid closure, and he was found to have a well-circumscribed metastasis to his lateral rectus muscle. Surgical excision cured his ocular symptoms, although he died 3 months later from brain and widespread metastases.