RESUMEN

We determined the incidence of hypercalciuria (HC) and its association with nephrocalcinosis and nephrolithiasis in 18 consecutive patients with Beckwith-Weidemann syndrome (BWS). Random, nonfasting urine samples were obtained from each patient. All patients had abdominal ultrasonography, most on several occasions. Four patients (22%) had HC. Of these, 2 had nephrocalcinosis, one had hyperechoic kidneys, and one had normal renal imaging. Serum calcium was normal in all patients with HC. Because we found that an increased prevalence in the occurrence of HC and its complications in a group of children with BWS, any child with BWS should be evaluated for HC.

Asunto(s)

Síndrome de Beckwith-Wiedemann/complicaciones , Trastornos del Metabolismo del Calcio/etiología , Trastornos del Metabolismo del Calcio/orina , Cálculos Renales/etiología , Nefrocalcinosis/etiología , Adolescente , Síndrome de Beckwith-Wiedemann/diagnóstico , Síndrome de Beckwith-Wiedemann/genética , Calcio/orina , Trastornos del Metabolismo del Calcio/diagnóstico , Trastornos del Metabolismo del Calcio/epidemiología , Niño , Preescolar , Creatinina/orina , Femenino , Hospitales Pediátricos , Humanos , Incidencia , Cálculos Renales/diagnóstico , Cálculos Renales/epidemiología , Masculino , Nefrocalcinosis/diagnóstico , Nefrocalcinosis/epidemiología , Ontario/epidemiología , Prevalencia , Factores de Riesgo

Asunto(s)

Donantes de Sangre , Trastornos del Metabolismo del Calcio/epidemiología , Calcio/sangre , Adolescente , Adulto , Factores de Edad , Argentina , Femenino , Humanos , Masculino , Persona de Mediana Edad , Factores Sexuales