RESUMEN
During the systematic search of active compounds from endophytic fungi, two new butyrolactones, namely aspernolides L (2) and M (4), together with four known compounds: 1-O-acetylglycerol (1), butyrolactone I (3), butyrolactone VI (5), and (+) alantrypinone (6) were characterized from the EtOAc extract of the endophytic fungus Aspergillus versicolor isolated from the roots of Pulicaria crispa (Asteraceae). Extensive spectroscopic analysis, including 1D, 2D NMR, and HRESIMS, was used to elucidate their structures. Compounds 1, 5, and 6 are reported for the first time from this fungus.
Asunto(s)
4-Butirolactona/análogos & derivados , 4-Butirolactona/aislamiento & purificación , Aspergillus/química , Pulicaria/microbiología , Etanol/química , Espectroscopía de Resonancia Magnética , Estructura Molecular , Raíces de Plantas/microbiología , Solventes/química , Espectrometría de Masa por Ionización de ElectrosprayRESUMEN
Two new ent-clerodane-type diterpenoids, compounds 1 and 2, were isolated from the aerial parts of Pulicaria wightiana, together with three known constituents. Their structures were established based on spectroscopic data, and their antibacterial activities were evaluated (Table 2).