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1.
An. psicol ; 40(2): 179-188, May-Sep, 2024. graf, tab
Artículo en Inglés | IBECS | ID: ibc-232713

RESUMEN

Los trastornos emocionales (TEs) son los trastornos más comunes entre la población joven. El desarrollo de programas preventivos de los TEs es fundamental para evitar su posible aparición. Los programas de prevención transdiagnósticos podrían presentar una ventaja sobre los existentes para mejorar las estrategias de regulación emocional. Así, el objetivo de este estudio ha sido determinar la viabilidad y eficacia preliminar de un programa breve basado en el Protocolo Unificado (PU). El proyecto consistió en un estudio piloto utilizando un diseño experimental de línea base múltiple. Nueve estudiantes universitarios recibieron un programa de 5 sesiones basado en el PU en formato grupal online. Se encontraron diferencias significativas después de la intervención en la regulación de las emociones, el apoyo social percibido y la evitación, con tamaños del efecto moderados-grandes (r de Cohen = .49 - .59). Estas mejoras mostraron aumentos en los seguimientos al mes y a los 3 meses. Esos resultados están en línea con los que muestran que los programas preventivos transdiagnósticos breves podrían ser útiles para la prevención de los TEs en población universitaria.(AU)


Emotional disorders (EDs) are the most common disorders among the young population. The development of preventive programs for EDs is essential to avoid their possible appearance. Transdiagnostic prevention programs could present an advantage over existing ones to im-prove emotional regulation strategies. Thus, the objective of this study has been to determine the preliminary feasibility and effectiveness of a brief program based on the Unified Protocol (UP). The project consisted of a pilot study using a multiple baseline experimental design. Nine university students received a 5-session program based on the UP in online-group format. Significant differences were found after the intervention for emo-tion regulation, perceived social support and avoidance, with moderate-large effect sizes (Cohen's r= .49-.59). These improvements showed in-creases at 1-month and 3-month follow-ups. Those results are in line with those showing that brief transdiagnostic preventive programs could be use-ful for the prevention of EDs in the university population.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Estudiantes/psicología , Salud Mental , Salud del Estudiante , Síntomas Afectivos , Prevención de Enfermedades , Proyectos Piloto , Psicología , Protocolos Clínicos
2.
Br J Nurs ; 33(16): S30-S35, 2024 Sep 05.
Artículo en Inglés | MEDLINE | ID: mdl-39250451

RESUMEN

Colostomy irrigation is a procedure that allows patients to achieve a certain degree of bowel control, and a period free of stoma effluent. It has the potential to improve quality of life, body image and confidence, and reduce patient anxiety. It may also help reduce odour and flatus, prevent/address peristomal skin irritation and alleviate constipation. Because it can reduce or eliminate the need for a colostomy bag, it may also cut expenditure on stoma appliances. However, colostomy irrigation is not offered to patients as standard. A protocol was drawn up to ensure colostomy irrigation was routinely offered to suitable patients and to provide them with a structured follow-up to ensure they were well supported throughout the first year of carrying out the procedure. Quality of life and the efficacy of colostomy irrigation can be monitored using questionnaires on these two issues. Two case studies demonstrate how patients' quality of life can improve when using colostomy irrigation as part of their stoma care routine.


Asunto(s)
Colostomía , Calidad de Vida , Irrigación Terapéutica , Humanos , Colostomía/enfermería , Irrigación Terapéutica/métodos , Femenino , Masculino , Protocolos Clínicos , Persona de Mediana Edad , Anciano
3.
J Nucl Med Technol ; 52(3): 208-211, 2024 Sep 05.
Artículo en Inglés | MEDLINE | ID: mdl-39237335

RESUMEN

Although guidelines for the use of 177Lu-PSMA-617 published by various organizations are important, they do not include all the essential, practical points necessary for a complete institutional protocol. Therefore, a brief survey was performed to assess key components of the 177Lu-PSMA-617 protocol before, during, and after delivery of therapy. This survey demonstrated the wide variability in many aspects of institutional protocols regarding determination of eligibility for and administration of 177Lu-PSMA-617 therapy. The real-world protocol details provided here from a variety of institutions may help new and established theranostic programs.


Asunto(s)
Protocolos Clínicos , Dipéptidos , Compuestos Heterocíclicos con 1 Anillo , Lutecio , Dipéptidos/uso terapéutico , Humanos , Estados Unidos , Encuestas y Cuestionarios , Neoplasias de la Próstata/radioterapia , Antígeno Prostático Específico
4.
BMC Psychiatry ; 24(1): 603, 2024 Sep 05.
Artículo en Inglés | MEDLINE | ID: mdl-39237898

RESUMEN

BACKGROUND: For Attention Deficit/Hyperactivity Disorder (ADHD) youth transitioning from child to adult services, protocols that guide the transition process are essential. While some guidelines are available, they do not always consider the effective workload and scarce resources. In Italy, very few guidelines are currently available, and they do not adhere to common standards, possibly leading to non-uniform use. METHODS: The present study analyzes 6 protocols collected from the 21 Italian services for ADHD patients that took part in the TransiDEA (Transitioning in Diabetes, Epilepsy, and ADHD patients) Project. The protocols' content is described, and a comparison with the National Institute for Clinical Health and Excellence (NICE) guidelines is carried out to determine whether the eight NICE fundamental dimensions were present. RESULTS: In line with the NICE guidelines, the dimensions addresses in the 6 analyzed documents are: early transition planning (although with variability in age criteria) (6/6), individualized planning (5/6), and the evaluation of transfer needs (5/6). All protocols also foresee joint meetings between child and adult services. The need to include the families is considered by 4 out of 6 protocols, while monitoring (2/6), and training programs (1/6) are less encompassed. In general, a highly heterogeneous picture emerges in terms of quality and quantity of regulations provided. CONCLUSIONS: While some solid points and core elements are in common with international guidelines, the content's variability highlights the need to standardize practices. Finally, future protocols should adhere more to the patients' needs and the resources available to clinicians.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad , Servicios de Salud Mental , Transición a la Atención de Adultos , Humanos , Trastorno por Déficit de Atención con Hiperactividad/terapia , Adolescente , Transición a la Atención de Adultos/normas , Servicios de Salud Mental/normas , Italia , Adulto , Guías de Práctica Clínica como Asunto , Masculino , Protocolos Clínicos/normas , Femenino , Adulto Joven
5.
Anesth Analg ; 139(4): 851-856, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39284137

RESUMEN

Prompt recognition and management of critical events is pivotal for the provision of safe anesthetic care. This requires a well-functioning team that focuses on effective communication, timely decision-making, and escalation of potential complications. We believe that variation in bedside care leads to "near-misses," adverse outcomes, and serious safety events (SSEs). The principles of an escalation culture have been used successfully in other highly reliable industries such as aviation, military, and manufacturing. We discuss here the introduction of a unique and compelling thought-process for developing an intraoperative escalation protocol that is specifically tailored for our institution. Inspired by a critical intraoperative event, this departmental protocol was developed based on an analysis of multispecialty literature and expert opinion to decrease the incidence of SSEs. It includes a stepwise approach and incorporates patient-specific information to guide team members who encounter dynamic clinical situations. The implementation of the protocol has facilitated continuous quality improvement through iterative education, improving communication, and enhancing decision-making. Concurrently, we have plans to incorporate technology and electronic decision support tools to enhance real-time communication, monitor performance, and foster a culture of safety.


Asunto(s)
Anestesiología , Humanos , Anestesiología/normas , Anestesiología/métodos , Cuidados Intraoperatorios/normas , Cuidados Intraoperatorios/métodos , Protocolos Clínicos/normas , Grupo de Atención al Paciente/normas , Complicaciones Intraoperatorias/prevención & control , Seguridad del Paciente/normas
6.
Nurs Open ; 11(9): e2232, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-39279282

RESUMEN

AIM: To develop a conceptual framework for nurses' protocol-based care decision-making. DESIGN: Miles & Huberman's bottom-up approach to developing conceptual frameworks was followed, using data collected from a multiple embedded case study examining protocol-based decision-making by nurses in three hospital wards within a university hospital in northern Spain. METHODS: The qualitative data from the case study, obtained through documentary analysis, observations, and interviews, underwent a secondary analysis consisting of four steps: data reduction, data display, comparison, and drawing conclusions. RESULTS: The framework for protocol-based care decision-making comprises four components: (1) protocol-based care, as a balance between standardisation and individualised care, (2) the process, (3) the context, and (4) the elements of protocol-based care decision-making. These components and their relationship as a context-dependent, linear, variable and multifactorial process, directly influenced by the perception of risk, are described and illustrated. CONCLUSIONS: This study provides a rigorous bottom-up framework for nurses' protocol-based care decision-making. The framework could be a valuable resource for managers, clinical nurses, educators, and researchers to guide and evaluate nurses' decision-making, leading to improved care quality and reduced variability in clinical practice. Furthermore, the framework lays a foundation for further research and practical applications. IMPACT: This study addressed the problem of understanding nurses' protocol-based care decision-making and the need for a specific conceptual framework. The main findings of the study contribute to the development of a rigorous bottom-up framework comprising four components of protocol-based care decision-making. The framework has the potential to improve care quality, reduce variability, enhance patient safety, and increase healthcare efficiency by guiding nurses' decision-making in various healthcare settings. NO PATIENT OR PUBLIC CONTRIBUTION: Patient or public contribution was not applicable since the study focused on nurses' decision making.


Asunto(s)
Investigación Cualitativa , Humanos , España , Toma de Decisiones , Enfermeras y Enfermeros/psicología , Protocolos Clínicos , Adulto , Femenino , Personal de Enfermería en Hospital/psicología , Masculino , Toma de Decisiones Clínicas/métodos
7.
J Drugs Dermatol ; 23(9): 790-791, 2024 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-39231073

RESUMEN

Platelet-rich concentrates (PRCs), derived from a patient's blood, are being used in various fields of medicine, including dermatology, for an increasing number of indications. Although considered a generally safe procedure for dermatologic indications, there have been reports in the last several years linking this treatment to cases of blood-borne infections including HIV and hepatitis.1 Patient safety should always be the primary focus for physicians and other health care professionals, and systems-based protocols should exist within care settings to minimize errors. Herein, we review our protocol to decrease the risk of complications related to transmission of blood-borne infections and other medical errors related to PRCs. J Drugs Dermatol. 2024;23(9)790-791. doi:10.36849/JDD.8166.


Asunto(s)
Errores Médicos , Plasma Rico en Plaquetas , Humanos , Errores Médicos/prevención & control , Seguridad del Paciente , Patógenos Transmitidos por la Sangre , Protocolos Clínicos , Dermatología/métodos , Dermatología/normas , Enfermedades de la Piel/terapia
8.
BJS Open ; 8(5)2024 Sep 03.
Artículo en Inglés | MEDLINE | ID: mdl-39226376

RESUMEN

BACKGROUND: Increased length of stay after surgery is associated with increased healthcare utilization and adverse patient outcomes. While enhanced recovery after surgery (ERAS) protocols have been shown to reduce length of stay after colorectal surgery in trial settings, their effectiveness in real-world settings is more uncertain. The aim of this study was to assess the impact of ERAS protocol implementation on length of stay after colorectal surgery, using real-world data. METHODS: In 2012, ERAS protocols were introduced at 15 Ontario hospitals as part of the iERAS study. A cohort of patients undergoing colorectal surgery treated at these hospitals between 2008 and 2019 was created using health administrative data. Mean length of stay was computed for the intervals before and after ERAS implementation. Interrupted time series analyses were performed for predefined subgroups, namely all colorectal surgery, colorectal surgery without complications, right-sided colorectal surgery, and left-sided colorectal surgery. Sensitivity analyses were then conducted using adjusted length of stay, accounting for length of stay predictors, including: patient age, sex, marginalization, co-morbidities, and diagnosis; surgeon volume of cases, years in practice, and colorectal surgery expertise; hospital volume; and other contextual factors, including procedure type and timing, surgical approach, and in-hospital complications. RESULTS: A total of 32 612 patients underwent colorectal surgery during the study interval. ERAS implementation led to a decrease in length of stay of 1.05 days (13.7%). Larger decreases in length of stay were seen with more complex surgeries, with a level change of 1.17 days (15.6%) noted for the subgroup of patients undergoing left-sided colorectal surgery. The observed decreases in length of stay were durable for the length of the study interval in all analyses. When adjusting for predictors of length of stay, the effect of ERAS implementation on length of stay was larger (reduction of 1.46 days). CONCLUSION: Introducing formal ERAS protocols reduces length of stay after colorectal surgery significantly, independent of temporal trends toward decreasing length of stay. These effects are durable, demonstrating that ERAS protocol implementation is an effective hospital-level intervention to reduce length of stay after colorectal surgery.


Asunto(s)
Recuperación Mejorada Después de la Cirugía , Tiempo de Internación , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Femenino , Anciano , Persona de Mediana Edad , Ontario , Cirugía Colorrectal , Análisis de Series de Tiempo Interrumpido , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/prevención & control , Protocolos Clínicos , Recto/cirugía
9.
Rev. Flum. Odontol. (Online) ; 3(65): 87-96, set-dez.2024. ilus
Artículo en Portugués | LILACS, BBO - Odontología | ID: biblio-1567859

RESUMEN

O objetivo do presente estudo foi estabelecer um protocolo clínico de aplicação do produto DSP Desensitizer Gluhem em dentes com exposição radicular sem perda de estrutura dentária, e fazer uma análise dissertativa sobre o principal componente desse produto: glutaraldeído, no tratamento da hipersensibilidade dentinária. Para isso, a paciente apresentou-se à Clínica Odontológica da UFF| Niterói ­ RJ, queixando-se de sensibilidade intensa ao frio nos elementos 13 e 34. Primeiramente, foram coletadas informações durante a anamnese, e ao exame clínico foi observada recessão gengival e exposição radicular nesses elementos, porém não havia perda de estrutura dentária. Inicialmente foi feita a avaliação do nível de dor, com uso da Escala Analógica de Dor que pontua os níveis de dor de 0 a 10, sendo 0 "nenhuma dor' e 10 "pior dor possível". Após o questionamento, fez-se a secagem da região com jato de ar e aplicou-se o dessensibilizante Gluhem em solução por toda região cervical do elemento 13 até a margem gengival por 40 segundos com posterior secagem e lavagem com água. Também foi feita a aplicação da formulação em gel no elemento 34 seguindo o mesmo protocolo. A paciente não reagiu a dor após o protocolo. Conclui-se que o produto DSP Gluhem tanto na apresentação de solução como em gel atuaram efetivamente na sintomatologia dolorosa da HDC nas duas aplicações realizadas.


The objective of the present study was to establish a clinical protocol for the application of the product GSP Desensitizer Gluhem in teeth with root exposure without loss of tooth structure, and to carry out a dissertation analysis on the main component of this product: glutaraldehyde, in the treatment of dentin hypersensitivity. For this, the patient went to the Dental Clinic of UFF| Niterói - RJ, complaining of intense sensitivity to cold in elements 13 and 34. First, information was collected during the anamnesis, and the clinical examination showed gingival recession and root exposure in these elements, but there was no loss of tooth structure. Initially, the pain level was evaluated using the Analog Pain Scale, which scores pain levels from 0 to 10, with 0 being "no pain" and 10 "worst possible pain". After questioning, the region was dried with an air jet and the desensitizing Gluhem solution was applied throughout the entire cervical region of element 13 up to the gingival margin for 40 seconds with subsequent drying and washing with water. The gel formulation was also applied to element 34 following the same protocol. The patient did not react to pain after the protocol. It is concluded that the product DSP Gluhem, both in solution and in gel presentation, effectively acted on the painful symptomatology of HDC in the two applications performed.


Asunto(s)
Humanos , Femenino , Adulto , Protocolos Clínicos , Glutaral/uso terapéutico , Sensibilidad de la Dentina , Desensibilizantes Dentinarios
11.
Curr Opin Ophthalmol ; 35(5): 369-375, 2024 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-39115058

RESUMEN

PURPOSE OF REVIEW: We describe the history, utilization, and series results of panretinal photocoagulation (PRP) and ranibizumab and provide an analysis of PRP and ranibizumab usage before versus after the publication of the 2-year and 5-year results of the Diabetic Retinopathy Clinical Research Network (DRCR.net) Protocol S trial. RECENT FINDINGS: Number of ranibizumabs performed began to increase and number of PRPs performed began to decrease in 2016. After publication of the 2-year results, there was significant negative trend in PRP services and significant positive trend in ranibizumab services (both P < 0.001). After publication of the 5-year results, there was significant negative trend in PRP services (P = 0.003). There were significant negative trends (all P < 0.001) in reimbursement factors for PRP from 2013 to 2020: average work RVU (wRVU), nonfacility physical expense RVU, facility PE RVU, malpractice RVU (MP RVU). SUMMARY: Both PRP and ranibizumab have undergone numerous trials comparing their efficacy to other treatment options or no treatment at all. The publication of the 2-year results of Protocol S was associated with an increase in utilization of ranibizumab and decrease in utilization of PRP, with continued decrease after the publication of the 5-year results.


Asunto(s)
Inhibidores de la Angiogénesis , Retinopatía Diabética , Inyecciones Intravítreas , Coagulación con Láser , Ranibizumab , Ranibizumab/uso terapéutico , Ranibizumab/administración & dosificación , Humanos , Inhibidores de la Angiogénesis/uso terapéutico , Inhibidores de la Angiogénesis/administración & dosificación , Retinopatía Diabética/cirugía , Retinopatía Diabética/terapia , Retinopatía Diabética/tratamiento farmacológico , Coagulación con Láser/métodos , Factor A de Crecimiento Endotelial Vascular/antagonistas & inhibidores , Protocolos Clínicos
12.
Am J Emerg Med ; 84: 87-92, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39106738

RESUMEN

BACKGROUND: Established protocols for implementing high-quality targeted temperature management (TTM) provide guidance concerning the cooling rate, duration of maintenance, and rewarming speed. However, whether compliant to TTM protocols results in improved survival and better neurological recovery has not been examined. METHODS: A retrospective cohort study enrolled 1141 survivors of non-traumatic adult cardiac arrest with a pre-arrest cerebral performance category (CPC) score of 1-2 from 2015 to 2020 at a tertiary medical center. Of the survivors, 330 patients who underwent TTM were further included. Patients with spontaneous hypothermia (<35 °C) (n = 107) and expired during the TTM (n = 21) were excluded. A total of 202 patients were thus enrolled. One hundred and ten patients underwent TTM that completely complied with the protocol (protocol-complaint group), but 92 patients deviated in some manner from the protocol (protocol non-compliant group). RESULTS: Fifty patients (50%) and 46 patients (50%) in the protocol-compliant and non-compliant groups, respectively, did not survive to hospital discharge. In the protocol-compliant group, 42 patients (38.2%) had favorable neurological recovery, compared with 32 patients (34.8%) in the protocol non-compliant group. After adjusting for age, initial shockable rhythm, witnessed collapse, and cardiopulmonary resuscitation duration, protocol non-compliant was associated with the poor neurological outcomes (aOR 2.44, 95% CI = 1.13-5.25), but not with in-hospital mortality (aOR 1.31, 95% CI = 0.70-2.47). The most common reason for noncompliance was a prolonged duration reaching the target temperature (n = 33, 58.7%). The number of phases of non-compliant was not significantly associated with in-hospital mortality or poor neurological recovery. CONCLUSION: Among cardiac arrest survivors undergoing TTM, those who did not receive TTM that in compliance with the protocol were more likely to experience poor neurological recovery than those whose TTM fully complied with the protocols. The most frequently identified deviation was a prolonged duration to reaching the target temperature.


Asunto(s)
Hipotermia Inducida , Humanos , Estudios Retrospectivos , Masculino , Femenino , Hipotermia Inducida/métodos , Persona de Mediana Edad , Anciano , Paro Cardíaco/terapia , Paro Cardíaco/mortalidad , Adhesión a Directriz , Reanimación Cardiopulmonar/métodos , Protocolos Clínicos , Sobrevivientes , Adulto
13.
Am J Emerg Med ; 84: 158-161, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39128170

RESUMEN

Traumatic brain injury (TBIs) necessitates a rapid and comprehensive medical response to minimize secondary brain injury and reduce mortality. Emergency medical services (EMS) clinicians serve a critical role in the management of prehospital TBI, responding during an initial phase of care with significant impact on patient outcomes. We used versions two and three of the Brain Trauma Foundation (BTF) Prehospital Guidelines for the Management of Traumatic Brain Injury and the NASEMSO National Model Clinical Guidelines to determine key elements for a TBI prehospital protocol and included common factors across sources such as recommendations concerning patient monitoring, hypoxia, hypotension, hyperventilation, cerebral herniation, airway management, hyperosmolar therapy, and transport destination. We then conducted a cross-sectional evaluation of publicly available statewide EMS clinical protocols in the US to determine the degree of alignment with national guidelines. We calculated descriptive statistics for each factor in the state protocols. Despite adoption of some evidence-based recommendations for a standard approach to the prehospital management of patients with TBI, we found significant variability in statewide EMS treatment protocols for management of severe TBI, especially in the recommended frequency of patient reassessment and for the management of suspected herniation. Most statewide protocols provided guidance regarding oxygenation, ventilation, and blood pressure management that aligned with evidence-based guidelines. While most protocols did address management of oxygenation and ventilation, one in four protocols had no specific guidance for managing hypoxia and only 31% of protocols recommended avoiding hyperventilation. For the management of suspected cerebral herniation, over half of statewide protocols recommended hyperventilation, whereas only 31% explicitly advised against hyperventilation regardless of TBI severity. Interestingly, 94% of protocols do not mention the use of hyperosmolar therapy for TBI patients, neither recommending use or avoidance of hyperosmolar therapy. In conclusion, we found inconsistent adoption of national recommendations in available statewide protocols for prehospital TBI management. We identified significant gaps and variation in statewide protocols regarding patient monitoring and reassessment, as well as in several key areas of severe TBI management.


Asunto(s)
Lesiones Traumáticas del Encéfalo , Protocolos Clínicos , Servicios Médicos de Urgencia , Humanos , Lesiones Traumáticas del Encéfalo/terapia , Servicios Médicos de Urgencia/normas , Estados Unidos , Guías de Práctica Clínica como Asunto , Estudios Transversales , Hipotensión/terapia , Hipotensión/etiología , Adhesión a Directriz/estadística & datos numéricos
14.
J Plast Reconstr Aesthet Surg ; 97: 41-49, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39137523

RESUMEN

BACKGROUND: Standardization of surgical protocols is an evolving issue owing to the low incidence of rare craniofacial clefts. In this article, we present our surgical management technique for repair of rare craniofacial clefts and evaluate the postoperative results. METHODS: This study was conducted from 2013 to 2022 and included patients who presented with craniofacial clefts. The results were assessed based on parents' satisfaction and objective evaluations by two independent observers. RESULTS: A total of 3679 patients presented with cleft anomalies; of these, 61 patients with 89 rare craniofacial clefts were observed with a prevalence of 2.42/100. The male to female ratio was 1:1.35. Craniofacial cleft "4" and "5" were the most common, with 17 (19.1%) and 16 (17.98%) patients, respectively. Multiple craniofacial clefts were observed in 37.7% of the patients. Associated craniofacial anomalies were found in 39.34% of the patients. The parents of 71.6% of the patients were very satisfied with the results. Based on the scores of two independent observers, 70.27% of the patients showed good results. CONCLUSION: The rare nature of craniofacial clefts and involvement of various structures make the standardization of surgical procedures very challenging. Our experience with these clefts will help new surgeons both in didactics and in technical aspects of patient management. KEY POINTS: 1. We share our experience with rare craniofacial clefts. 2. Each cleft presents with its own unique reconstructive challenges. The literature describes many techniques for each type of cleft, all with multiple permutations. We present a simplified technique that has worked for us over the years for all Tessier clefts.


Asunto(s)
Labio Leporino , Fisura del Paladar , Procedimientos de Cirugía Plástica , Humanos , Masculino , Femenino , Fisura del Paladar/cirugía , Procedimientos de Cirugía Plástica/métodos , Labio Leporino/cirugía , Preescolar , Lactante , Niño , Satisfacción del Paciente , Protocolos Clínicos , Adolescente , Resultado del Tratamiento , Anomalías Craneofaciales/cirugía
15.
Rev Med Interne ; 45(9): 559-599, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-39191627

RESUMEN

Because Systemic Lupus Erythematosus (SLE) is a rare disease, and due to the significant prognostic impact of early management, a diagnosis confirmed by a physician with experience in SLE is recommended, for example from an expert center. Once the diagnosis is confirmed, existing manifestations should be identified in particular, renal involvement by an assessment of proteinuria, disease activity and severity should be determined, potential complications anticipated, associated diseases searched for, and the patient's socioprofessional and family context noted. Therapeutic management of SLE includes patient education on recognizing symptoms, understanding disease progression as well as when they should seek medical advice. Patients are informed about routine checkups, treatment side effects, and the need for regular vaccinations, especially if they are receiving immunosuppressive treatment. They are also advised on lifestyle factors such as the risks of smoking, sun exposure, and dietary adjustments, especially when they are receiving corticosteroids. The importance of contraception, particularly when teratogenic medications are being used, and regular cancer screening are emphasized. Support networks can help relieve a patient's isolation. The first-line medical treatment of SLE is hydroxychloroquine (HCQ), possibly combined with an immunosuppressant and/or low-dose corticosteroid therapy. The treatment of flares depends on their severity, and typically involves HCQ and NSAIDs, but may be escalated to corticosteroid therapy with immunosuppressants or biologic therapies in moderate to severe cases. Because there is no curative treatment, the goals of therapy are patient comfort, preventing progression and flares, and preserving overall long-term health and fertility. The frequency of follow-up visits depends on disease severity and any new symptoms. Regular specialized assessments are necessary, especially when treatment changes, but a frequency of every 3 to 6 months is recommended during periods of remission and monthly during active or severe disease, especially in children. These assessments include both clinical and laboratory tests to monitor complications and disease activity, with specific attention to proteinuria.


Asunto(s)
Lupus Eritematoso Sistémico , Humanos , Lupus Eritematoso Sistémico/diagnóstico , Lupus Eritematoso Sistémico/terapia , Lupus Eritematoso Sistémico/complicaciones , Francia/epidemiología , Inmunosupresores/uso terapéutico , Inmunosupresores/efectos adversos , Protocolos Clínicos , Femenino
16.
Breastfeed Med ; 19(8): 575-587, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39186728

RESUMEN

Background: The Academy of Breastfeeding Medicine revised the 2015 version of this clinical protocol to review the evidence and provide recommendations related to breastfeeding promotion in the prenatal period. Key Information: Promoting and normalizing breastfeeding in the prenatal period can improve breastfeeding outcomes including initiation and duration of breastfeeding. Ideally, prenatal interventions should be a part of a comprehensive longitudinal breastfeeding support program. Recommendations: Clinicians or other health workers should discuss breastfeeding at each prenatal visit. Counseling topics should include the health benefits of breastfeeding versus not breastfeeding, the basics of breastfeeding (e.g., physiology, positioning), what to expect of hospital-based and immediate postpartum breastfeeding support (i.e., Baby-Friendly Ten Steps), and the risks of unnecessary supplementation. Medical, anatomical, and other risk factors for breastfeeding challenges should be identified, and targeted anticipatory guidance should be given. Prenatal counseling should include distribution of structured breastfeeding education at low literacy levels and in the parent's preferred language. Counseling should be culturally sensitive and patient-centered, including family members when appropriate. Prenatal support may integrate various health workers (e.g., medical doctors, midwives, community health workers, lactation consultants, among others) and include various modalities including telecommunication. Enhancing breastfeeding education for prenatal care providers is also imperative. Additional themes related to implementation of recommendations for specific populations are also reviewed.


Asunto(s)
Lactancia Materna , Promoción de la Salud , Atención Prenatal , Humanos , Femenino , Embarazo , Recién Nacido , Consejo , Protocolos Clínicos , Academias e Institutos
17.
Medicina (Kaunas) ; 60(8)2024 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-39202619

RESUMEN

Background and Objectives: Minimally invasive trauma management, including interventional radiology and non-operative approaches, has proven effective. Consequently, our hospital established a trauma IVR protocol called "Ohta Nishinouchi Hospital trauma protocol (ONH trauma protocol) in 2013, mainly for trunk trauma. However, the efficacy of the ONH trauma protocol has remained unverified. We aimed to assess the protocol's impact using interrupted time-series analysis (ITSA). Materials and Methods: This retrospective cohort study was conducted at Ohta Nishinouchi hospital, a tertiary emergency hospital, from January 2004 to December 2019. We included patients aged ≥ 18 years who presented to our institution due to severe trauma characterized by an Abbreviated Injury Scale of ≥3 in any region. The primary outcome was the incidence of in-hospital deaths per 100 transported patients with trauma. Multivariable logistic regression analysis was conducted with in-hospital mortality as the outcome, with no exposure before protocol implementation and with exposure after protocol implementation. Results: Overall, 4558 patients were included in the analysis. The ITSA showed no significant change in in-hospital deaths after protocol induction (level change -1.49, 95% confidence interval (CI) -4.82 to 1.84, p = 0.39; trend change -0.044, 95% CI -0.22 to 0.14, p = 0.63). However, the logistic regression analysis revealed a reduced mortality effect following protocol induction (odds ratio: 0.50, 95% CI: 0.37 to 0.66, p < 0.01, average marginal effects: -3.2%, 95% CI: -4.5 to -2.0, p < 0.01). Conclusions: The ITSA showed no association between the protocol and mortality. However, before-and-after testing revealed a positive impact on mortality. A comprehensive analysis, including ITSA, is recommended over before-and-after comparisons to assess the impact of the protocol.


Asunto(s)
Mortalidad Hospitalaria , Análisis de Series de Tiempo Interrumpido , Humanos , Femenino , Estudios Retrospectivos , Masculino , Persona de Mediana Edad , Adulto , Anciano , Protocolos Clínicos , Estudios de Cohortes , Pelvis/lesiones , Modelos Logísticos , Japón/epidemiología , Torso/lesiones
18.
Respir Care ; 69(9): 1212-1213, 2024 Aug 24.
Artículo en Inglés | MEDLINE | ID: mdl-39181718
19.
Tech Coloproctol ; 28(1): 111, 2024 Aug 20.
Artículo en Inglés | MEDLINE | ID: mdl-39162907

RESUMEN

BACKGROUND: This study presents a laparoscopic surgical protocol for right hemicolectomy and D3 lymphadenectomy (R-D3L) in right colon cancer and reports the oncological outcomes based on a prospective series. METHODS: The study comprises two phases. In the first phase, a dynamic demonstration of the R-D3L surgical protocol is provided through textual explanation, illustrations, and edited surgical videos. The protocol emphasizes technical steps such as dissection of the embryological plane of the right mesocolon, high tie of ileocolic vessels, surgical trunk of Gillot dissection, and high tie of superior right colic vein (SRCV). In the second phase, a prospective observational study was conducted involving patients undergoing R-D3L surgery with this protocol between July 2015 and July 2021. Demographic, perioperative, and postoperative variables are analyzed, along with anatomopathological variables and oncological outcomes. RESULTS: A total of 33 patients were analyzed. Median operative time was 202 min. Perioperative bleeding occurred in 6%. Postoperative complications were mild (Clavien-Dindo III in 2%). Postoperative ileus was observed in 15%. No anastomotic dehiscence was reported. The median postoperative stay was 7 days. The median number of resected lymph nodes was 26, with 27% having positive nodes and 70% were classified as stage T3 or T4. After a median follow-up of 45 months, local recurrence, distant recurrence, and carcinomatosis rates were 0%. Mortality rate from other causes was 9%. CONCLUSION: The surgical protocol shown in the present study could help in the implementation of this technique in those units that consider it appropriate.


Asunto(s)
Colectomía , Neoplasias del Colon , Laparoscopía , Escisión del Ganglio Linfático , Tempo Operativo , Complicaciones Posoperatorias , Humanos , Neoplasias del Colon/cirugía , Neoplasias del Colon/patología , Femenino , Masculino , Escisión del Ganglio Linfático/métodos , Anciano , Estudios Prospectivos , Persona de Mediana Edad , Laparoscopía/métodos , Laparoscopía/efectos adversos , Colectomía/métodos , Colectomía/efectos adversos , Colectomía/normas , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/epidemiología , Resultado del Tratamiento , Anciano de 80 o más Años , Adulto , Protocolos Clínicos , Estadificación de Neoplasias , Mesocolon/cirugía , Tiempo de Internación/estadística & datos numéricos
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