RESUMEN

We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we suggest that AMIN domains mediate the targeting of periplasmic or extracellular proteins to specific regions of the bacterial envelope.

Asunto(s)

Proteínas Bacterianas/química , Proteínas Periplasmáticas/química , Secuencia de Aminoácidos , Proteínas Bacterianas/análisis , Modelos Genéticos , Datos de Secuencia Molecular , Proteínas Periplasmáticas/análisis , Estructura Secundaria de Proteína , Estructura Terciaria de Proteína , Alineación de Secuencia