RESUMEN

Melanoma is a malignant tumor with the highest growth rate in the incidence and is the leading cause of death due to skin cancers. In Poland, approximately 1500 cases of melanoma are detected annually in advanced or metastatic stages. Intensive preventive measures can contribute to its early-stage diagnosis, consequently reducing the number of fatalities. The aim of the study was to assess the occurrence of melanoma risk factors among the residents of Silesia region and their knowledge about the diagnosis and prevention of this cancer. An original questionnaire was used in the study, and its completion was anonymous. The study was conducted among the residents of the Silesian Voivodeship. A total of 400 (100%) individuals were examined. Among them were 243 women and 157 men. The participants' ages ranged from 16 to 84 years (mean age = 34.38 ±â€…18.39). The participants were burdened with melanoma development risk factors such as fair skin complexion (235; 58.75%), having more than 50 pigmented lesions (158; 39.50%) and sunburns (105; 26.25%). Over 40% (166; 41.50%) of the participants had never examined their pigmented lesions. A staggering 78% (311; 77.75%) of the respondents had never undergone dermatoscopic examination, and over 50% (215; 53.75%) did not know what this examination entailed. Just under 16% (63; 15.75%) of the participants stated that their family doctor had examined their pigmented lesions, and almost % (154; 97.47%) of those with numerous pigmented lesions had never been referred to a dermatologist for dermatoscopy. The surveyed residents of the Silesian Voivodeship were burdened with numerous risk factors for melanoma development, with the most common being fair skin complexion, having more than 50 pigmented lesions, and sunburns. The knowledge of the participants regarding the diagnosis and prevention of melanoma development was insufficient, thus highlighting the necessity for conducting systematic educational initiatives in the mentioned field. These initiatives should ultimately lead to the preservation of health and life, as well as the maintenance of its high quality.

Asunto(s)

Melanoma , Neoplasias Cutáneas , Humanos , Masculino , Adulto , Femenino , Persona de Mediana Edad , Melanoma/prevención & control , Melanoma/diagnóstico , Melanoma/epidemiología , Polonia/epidemiología , Neoplasias Cutáneas/prevención & control , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/epidemiología , Anciano , Adulto Joven , Adolescente , Anciano de 80 o más Años , Factores de Riesgo , Conocimientos, Actitudes y Práctica en Salud , Encuestas y Cuestionarios , Detección Precoz del Cáncer/métodos , Detección Precoz del Cáncer/estadística & datos numéricos

RESUMEN

I n t r o d u c t i o n: Despite increased awareness of malnutrition and improved nutrition-related policies, there are still cases of deterioration of nutritional status during hospitalisation. NutritionDay is an audit organised by the European Society for Clinical Nutrition and Metabolism (ESPEN), the Medical University of Vienna and the Friedrich-Alexander University Erlangen-Nürnberg (FAU) to prevent the onset of malnutrition and to improve hospital policies to deal with this problem. The aim of the study was to analyse the results of the audit with regard to factors that may contribute to the deterioration of a patients' nutritional status in hospital setting. Materials and Methods: This cross-sectional study was performed in a tertiary teaching hospital and was part of an international audit. The questionnaires used were provided by the nutritionDay office, and included information on weight loss, patients' appetite, dietary restrictions, food intake and reasons for food rejection during hospital stay. R e s u l t s: Of the examined patients, 61% reported weight loss prior to the current hospital stay. We identified 25 patients who did not consume a whole portion of their main meal on the day the audit took place. Approximately 17% of the patients' complaints could be resolved within a hospital ward. C o n c l u s i o n s: Hospital patients often eat less than a standard meal portion. Identifying the reasons for meal rejection may be helpful for development of standards for nutritional care in the hospitals.

Asunto(s)

Desnutrición , Estado Nutricional , Humanos , Estudios Transversales , Masculino , Femenino , Persona de Mediana Edad , Desnutrición/epidemiología , Desnutrición/prevención & control , Servicio de Alimentación en Hospital/normas , Polonia , Adulto , Anciano , Hospitales Universitarios , Comidas , Encuestas y Cuestionarios

RESUMEN

Misinformation surrounding crises poses a significant challenge for public institutions. Understanding the relative effectiveness of different types of interventions to counter misinformation, and which segments of the population are most and least receptive to them, is crucial. We conducted a preregistered online experiment involving 5228 participants from Germany, Greece, Ireland, and Poland. Participants were exposed to misinformation on climate change or COVID-19. In addition, they were pre-emptively exposed to a prebunk, warning them of commonly used misleading strategies, before encountering the misinformation, or were exposed to a debunking intervention afterwards. The source of the intervention (i.e. the European Commission) was either revealed or not. The findings show that both interventions change four variables reflecting vulnerability to misinformation in the expected direction in almost all cases, with debunks being slightly more effective than prebunks. Revealing the source of the interventions did not significantly impact their overall effectiveness. One case of undesirable effect heterogeneity was observed: debunks with revealed sources were less effective in decreasing the credibility of misinformation for people with low levels of trust in the European Union (as elicited in a post-experimental questionnaire). While our results mostly suggest that the European Commission, and possibly other public institutions, can confidently debunk and prebunk misinformation regardless of the trust level of the recipients, further evidence on this is needed.

Asunto(s)

COVID-19 , Comunicación , Unión Europea , Confianza , Humanos , COVID-19/epidemiología , COVID-19/prevención & control , Masculino , Femenino , Adulto , Polonia , Alemania , Cambio Climático , Grecia , Encuestas y Cuestionarios , Irlanda , SARS-CoV-2 , Persona de Mediana Edad , Adulto Joven

RESUMEN

The Polish standard of treatment with racemic ketamine for patients with depressive disorders was developed by a Working Group appointed by the National Consultant in the field of psychiatry. Despite the wide range of available medications, as many as one-third of depressed patients do not respond to standard antidepressant treatment, raising the need for an ongoing search for new effective and safe therapies. In recent years, the possible role of overactivity of the glutamatergic system in the etiopathogenesis of depression has again attracted the attention of many experts. The possibility of using substances with a modulating effect on the glutamatergic system in the treatment of depressive disorders has been postulated, among others, the long-known anesthetic ketamine, which is a noncompetitive NMDA receptor antagonist. This paper summarizes the results of studies on the efficacy and safety of racemic ketamine (administered intravenously) in the treatment of patients with depressive symptoms in the course of both unipolar and bipolar affective disorder, and, meeting the expectations of many practicing psychiatrists wishing to broaden the range of therapies offered to their patients, presents recommendations on indications, contraindications, precautions and the treatment regimen itself with intravenous ketamine for patients with mood disorders.

Asunto(s)

Antidepresivos , Ketamina , Psiquiatría , Humanos , Antidepresivos/uso terapéutico , Trastorno Depresivo/tratamiento farmacológico , Ketamina/uso terapéutico , Polonia , Resultado del Tratamiento

RESUMEN

From Darwin through Wittgenstein to contemporary scientific investigations, it has been argued humans tend to view facial expressions through a mentalistic lens. According to this view, when looking at someone's expressive face, we see emotion and are unable to describe the face in behavioral terms, i.e., name the details of facial movements. At the same time, however, a growing body of work shows cultures in fact differ in the degree of importance they attribute to mental states and willingness to discuss them. Is this variation reflected in the linguistic coding of facial expressions? To explore this, we conducted two facial expression naming tasks targeting mental states and facial movements with speakers of Maniq (Austroasiatic, Thailand) and Polish (Indo-European, Poland), representing highly diverse linguistic and cultural settings. We found that, while Polish speakers conformed with the predicted orientation towards mental states, this did not hold for Maniq speakers. The Maniq were instead oriented towards behavioral aspects of faces, naming them more frequently, more precisely, and with higher consensus, compared to the Polish. These differences are carved into the Maniq and Polish lexicons, suggesting diverse cultures exhibit differential specialization in verbalizing expressive faces.

Asunto(s)

Expresión Facial , Humanos , Masculino , Femenino , Adulto , Polonia , Tailandia , Emociones/fisiología , Cultura , Adulto Joven , Lenguaje

RESUMEN

Positive body image is crucial in fostering self-esteem, mental well-being, and positive social functioning. However, our understanding of its development and role in school-aged children remains limited due to a scarcity of measures available for this age group across various countries and cultures. To bridge this gap, the aim of this study was to adapt the Body Appreciation Scale-2 for Children (BAS-2C) for Polish children aged 8-13 years. A total of 206 children completed BAS-2C to measure positive body image, the Figures Rating Scale to measure body satisfaction, and the Self-Perception Profile for Children to measure self-esteem. Parents provided information about their child's weight and height, which enabled analysis of a child's BMI. The results showed that the Polish version of BAS-2C exhibited a unidimensional factor structure, invariance across sex and age groups, and also provided evidence of very good internal consistency, test-retest reliability, and construct validity. BAS-2C scores were correlated positively with Figures Rating Scale, physical appearance and global self-esteem and were related negatively to age and BMI index, and weight group. Moreover, our research indicates that in older children, there are stronger correlations between positive body image and both global and physical appearance self-esteem, compared to younger children. The Polish version of BAS-2C has excellent psychometric properties and is appropriate for use with children aged 8-13 years.

Asunto(s)

Imagen Corporal , Psicometría , Autoimagen , Humanos , Niño , Femenino , Masculino , Adolescente , Psicometría/métodos , Polonia , Imagen Corporal/psicología , Encuestas y Cuestionarios , Reproducibilidad de los Resultados , Índice de Masa Corporal

RESUMEN

Advances in the diagnosis and treatment of adrenocortical carcinoma (ACC), along with the development of new therapeutic and diagnostic methods, have prompted a team of experts to formulate the first Polish guidelines for managing ACC. This article presents the diagnostic and therapeutic recommendations resulting from the discussion of specialists from various medical specialities, who participated in a series of online meetings aimed at developing consistent and effective recommendations under the National Oncology Strategy. These guidelines aim to optimise ACC treatment in Poland through coordinated efforts of multidisciplinary specialist teams, ensuring an effective and modern approach.

Asunto(s)

Neoplasias de la Corteza Suprarrenal , Carcinoma Corticosuprarrenal , Humanos , Carcinoma Corticosuprarrenal/diagnóstico , Carcinoma Corticosuprarrenal/terapia , Polonia , Neoplasias de la Corteza Suprarrenal/diagnóstico , Neoplasias de la Corteza Suprarrenal/terapia , Guías de Práctica Clínica como Asunto , Femenino , Masculino , Oncología Médica/normas

RESUMEN

BACKGROUND The purpose of the study was to determine the level of antihemagglutinin antibodies in the serum of patients in the geriatric population in Doctor's Surgery NZOZ Nucleus Warsaw, Poland, during the epidemic season 2021/2022 using the hemagglutination inhibition assay (HAI), according to anti-influenza and anti-COVID-19 vaccination, age, and sex. MATERIAL AND METHODS Serum samples taken from 256 patients aged 65 to 99 years were examined for anti-hemagglutinin antibodies and protective levels of antibodies against antigens: A/Victoria/2570/2019 (H1N1)pdm09, A/Cambodia/e0826360/2020(H3N2), B/Washington/02/2019 (B/Victoria lineage), and B/Phuket/3073/2013 (B/Yamagata lineage) of the quadrivalent influenza vaccine for epidemic season 2021/2022. RESULTS The highest protective level, ie, the percentage of people with antibody titers ≥40 was 87.5% and was recorded for subtype A/Cambodia/e0826360/2020(H3N2), the dominant type causing infections in the epidemic season 2021/2022 confirmed by molecular biology methods. Geometric mean titer (GMT) values and protective levels for B/Washington/02/2019 (B/Victoria lineage) antigen were higher for men than women (respectively 38.4 vs 67.6; P<0.001 and 58.0% vs 74.6%; P<0.001). The protective levels of antibodies among patients vaccinated vs unvaccinated against COVID-19 were higher for B/Washington/02/2019 (B/Victoria lineage) and B/Phuket/3073/2013 (B/Yamagata lineage) antigens (64.2% vs 44.4%; P=0.023 and 78.6% vs 55.6%; P=0.004). GMT values for vaccinated against COVID-19 were also higher. There were no significant differences between younger (65-79 years) and older (≥80 years) seniors. CONCLUSIONS The analysis shows differences in the level of individual antibodies, GMT and the protective level depending on subtypes of influenza A or B virus, B/Victoria or B/Yamagata lineage, sex, and previous vaccination history against influenza and COVID-19.

Asunto(s)

Anticuerpos Antivirales , COVID-19 , Vacunas contra la Influenza , Gripe Humana , SARS-CoV-2 , Humanos , Anciano , Polonia/epidemiología , Masculino , Femenino , Anticuerpos Antivirales/sangre , Anticuerpos Antivirales/inmunología , Gripe Humana/prevención & control , Gripe Humana/inmunología , Gripe Humana/epidemiología , Vacunas contra la Influenza/inmunología , Anciano de 80 o más Años , COVID-19/prevención & control , COVID-19/inmunología , COVID-19/epidemiología , SARS-CoV-2/inmunología , Vacunas contra la COVID-19/inmunología , Factores Sexuales , Vacunación , Subtipo H3N2 del Virus de la Influenza A/inmunología , Glicoproteínas Hemaglutininas del Virus de la Influenza/inmunología , Factores de Edad , Subtipo H1N1 del Virus de la Influenza A/inmunología , Pruebas de Inhibición de Hemaglutinación/métodos , Estaciones del Año

RESUMEN

Background: Due to the need to increase social awareness about dementia and the needs of patients living with dementia in Poland, the Razem przed siebie (eng. Forward with Dementia) campaign was created. The aim of the study was to evaluate its effectiveness. Methods: To disseminate key campaign messages to the target audiences (people with dementia, carers, health and social care professionals [HSCP] and general public) a website, social and traditional media promotions, webinars and social activities were created. The campaign ran between September 2021 and April 2022. Mixed methods (online survey, reach estimates and interviews) were used to evaluate the campaign. Results: Almost 1,300 people visited the website during the campaign period. Of these, 55 carers and HSCP responded to the online survey. The most read section of the website was Understanding the diagnosis (carers [56% of 25] and HSCP [80% out of 30]). The website was mostly accessed by carers (68%) and HSCP (66.7%) through word-of-mouth recommendations. 80% carers and 90% HSCP found the website very or extremely helpful. Over 90% of carers and HSCP expressed an intention to revisit the website. Based on 31 interviews, campaign effects, change mechanisms and limitations were identified. Campaign events elicited positive emotions among people with dementia, providing them with a feeling of belonging and engagement. Esteeming personal interactions over informational campaign materials, those with dementia felt acknowledged and empowered by the events. Carers also reported positive experiences and increased interest and knowledge, though they expressed disappointment with the lack of respite care, an issue beyond the campaign's scope. HSCP perceived the campaign events positively and identified significant gaps in the dementia care system. Conclusion: Evaluation of the Razem przed siebie campaign revealed successes and limitations. While effectively incorporating anti-stigma campaign recommendations and enhancing social health for individuals with dementia, the campaign clearly showed the pressing need for systemic solutions. Despite positive perception of the campaign, there is a need for a better diagnostic and post-diagnostic support for people with dementia and their carers.

Asunto(s)

Demencia , Promoción de la Salud , Humanos , Polonia , Masculino , Femenino , Promoción de la Salud/métodos , Persona de Mediana Edad , Cuidadores/psicología , Encuestas y Cuestionarios , Anciano , Internet , Adulto , Conocimientos, Actitudes y Práctica en Salud , Concienciación

RESUMEN

OBJECTIVE: Aim: Type 2 diabetes mellitus (T2DM) is a widespread disease that leads to many complications if not adequately controlled. The pandemic and its limitations on healthcare access impaired the management of chronic conditions. The aim of our study was to examine its effects in context of different antidiabetic therapies on key health related factors in patients with T2DM. PATIENTS AND METHODS: Materials and Methods: To the study we enrolled 598 adult patients with diagnosed T2DM treated in diabetology outpatient department of the University Clinical Centre (UCC) of the Medical University of Warsaw. Data on body weight, glycated hemoglobin (HbA1c), and creatinine concentration were collected throughout the first COVID-19 pandemic wave and compared to the results obtained before the 4th of March, 2020 (1st confirmed COVID-19 case in Poland). RESULTS: Results: The HbA1c mean baseline level was 7.15% (±1.39) and increased significantly (7.34% (±1.37), p=0.02) during observation. Importantly, the attendance of patients for HbA1c testing decreased by 57.82% in comparison to the pre-pandemic period. Similarly, creatinine concentrations increased (from 1.27 mg/dl (±0.76) to 1.34 mg/dl (±1.02), (p=0.004)). The increase in creatinine concentration was significantly lower in the group treated with regimens including metformin compared to other regimens. Somewhat surprisingly, the mean body mass remained unchanged. CONCLUSION: Conclusions: The pandemic period had a significant impact on the tested biochemical parameters. The lesser changes of renal parameters in the group of patients treated with metformin confirms its nephroprotective effect and its value as a first-line treatment in T2DM.

Asunto(s)

COVID-19 , Creatinina , Diabetes Mellitus Tipo 2 , Hemoglobina Glucada , Hipoglucemiantes , Humanos , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Hemoglobina Glucada/análisis , Masculino , Hipoglucemiantes/uso terapéutico , Femenino , COVID-19/epidemiología , Polonia , Persona de Mediana Edad , Creatinina/sangre , Anciano , SARS-CoV-2 , Accesibilidad a los Servicios de Salud/estadística & datos numéricos , Adulto , Control Glucémico

RESUMEN

OBJECTIVE: Aim: To analyze and summarize the implementation of telemedical solutions in geriatrics and gerontology within the Polish healthcare sector, aiming to develop innovative strategies for improving elderly care through telemedical technologies. PATIENTS AND METHODS: Materials and Methods: An interdisciplinary pilot project in geriatrics was implemented, focusing on health, organizational, and technological areas. The project involved continuous monitoring of health parameters, remote consultations, and the use of telemedical devices and platforms. Key data collection tools included digital clinimetric outcomes from the FRA-MNA-SARC model, with data transmitted to a telemedical platform. RESULTS: Results: The pilot project demonstrated significant positive outcomes for senior participants. Continuous monitoring of health parameters allowed for early detection and timely intervention, leading to noticeable improvements in chronic disease management. This proactive approach reduced emergency hospital visits and enhanced overall health stability. The medication adherence support system, with automated reminders, ensured patients took their medications as prescribed, resulting in improved compliance and health outcomes. Telemedical solutions efficiently reduced the need for frequent in-person visits, allowing healthcare providers to monitor progress and adjust therapies in real-time. The project also effectively engaged patients and caregivers, increasing confidence in health management and providing valuable support and real-time information. CONCLUSION: Conclusions: Implementing telemedical solutions in geriatrics within the Polish healthcare sector shows significant potential to improve elderly care. Telemedicine can effectively support chronic disease management, enhance seniors' quality of life through continuous health monitoring, and provide a practical framework for personalized and efficient healthcare delivery.

Asunto(s)

Geriatría , Telemedicina , Humanos , Telemedicina/organización & administración , Polonia , Geriatría/organización & administración , Anciano , Proyectos Piloto , Masculino , Femenino , Atención a la Salud/organización & administración , Anciano de 80 o más Años , Servicios de Salud para Ancianos/organización & administración

RESUMEN

The emergence of the Linear Pottery Culture (LBK) during the Neolithic period within Polish territory 5400-4900 BC, introduced plant cultivation, yet the definitive list of cultivated species remains debated. This study examines plant assemblages (fruits, seeds, pollen, and spores) from the LBK settlement in Biskupice, southern Poland, aiming to identify cultivated and wild species used during the development of the first stable settlements in the Carpathian Foothills. Due to extensive sampling, Biskupice yielded over 11,000 macroscopic plant specimens, enabling detailed analysis of plant diversity, distribution, and implications for agrarian and dietary practices. The analysis revealed a focus on emmer and einkorn wheat cultivation, with barley playing a minor role, alongside evidence of flax and pulses. Radiocarbon dating supported the settlement's existence in the 6th millennium BCE, and confirmed the use of barley. However, a younger date excluded bread wheat cultivation at this site. The plant assemblage included a diverse array of herbaceous wild plants like black bindweed, fat hen and brome species, suggesting their economic use. Additionally, the presence of cockspur grass, linked with Southeast Asia, indicates alternative migration routes of weeds in Europe, as supported by radiocarbon dating. Palynological analysis suggests existence of nearby cereal plots or the processing of cereals at the settlement, supporting archaeological evidence.

Asunto(s)

Arqueología , Biodiversidad , Polonia , Humanos , Historia Antigua , Agricultura/historia , Triticum/crecimiento & desarrollo , Productos Agrícolas/crecimiento & desarrollo , Datación Radiométrica , Hordeum/crecimiento & desarrollo

RESUMEN

PURPOSE: The Scored Patient-Generated Subjective Global Assessment (PG-SGA©) is a validated nutritional screening, assessment, triage, and monitoring tool. The aim of this study was to perform translation, cultural adaptation, linguistic, and content validation of the translated and culturally adapted version of the PG-SGA for the Polish setting. METHODS: The study was performed in concordance with the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Principles. Patients (n = 174) and healthcare professionals (HCPs, n = 188) participated in the study. Comprehensibility and difficulty were assessed by patients for the PG-SGA Short Form, and by HCPs for the professional component. Content validity was assessed for the full PG-SGA by HCPs only. Evaluations were operationalized by a 4-point scale. Item and scale indices were calculated using the average item ratings divided by the number of respondents. Item indices < 0.78 required further analysis of the item, while scale indices ≥ 0.90 were defined as excellent and 0.80-0.89 as acceptable. RESULTS: The PG-SGA Short Form was rated as excellent for content validity (Scale-CVI = 0.90) by HCPs and easy to comprehend (Scale-CI = 0.96) and use (Scale-DI = 0.94) by patients. The professional component of the PG-SGA was perceived as acceptable for content validity (Scale-CVI = 0.80), comprehension (Scale-CI = 0.87), and difficulty (Scale-DI = 0.80). The physical exam was rated the least comprehensible and the most difficult, and with the lowest content validity. We found significant differences in scale indices (p < 0.05 for all) between HCPs with different professions and between those being familiar with PG-SGA and not. CONCLUSION: Translation and cultural adaptation of the PG-SGA for the Polish setting preserved the purpose and conceptual meaning of the original PG-SGA. Validation revealed that the Polish version of PG-SGA is well understood and easy to complete by patients and professionals, and is considered relevant by professionals. However, detailed results indicate the need for appropriate training of the Polish HCPs, especially physicians and nurses, mainly in the worksheets related to the metabolic demand and physical exam.

Asunto(s)

Traducciones , Humanos , Femenino , Masculino , Polonia , Persona de Mediana Edad , Adulto , Reproducibilidad de los Resultados , Anciano , Evaluación Nutricional , Encuestas y Cuestionarios/normas , Personal de Salud/psicología , Adulto Joven , Psicometría/métodos

RESUMEN

BACKGROUND: The level of health behavior of physical education teachers and people preparing to perform this profession is important from the point of view of the need to play the role of a health promoter - an authority in the promotion of health culture. The aim of the study was to assess the level of teachers' health behaviors of physical education teachers and students, as well as to search for their determinants. MATERIAL AND METHODS: The research covered 127 teachers and 173 physical education students. Standardized questionnaire tools were used to assess the level of health behaviors (Juczynski Health Behavior Inventory) and physical activity (International Physical Activity Questionnaire). RESULTS: Teachers demonstrate a higher level of health behaviors than students. Most respondents achieved an average level of the general health behavior index (HBI) (53.1% of teachers, 52.3% of students), while a high level - 26.8% of teachers, 19.8% of students and a low level - 19.9% of teachers and 27.7% of students. Female gender and teaching profession are significant predictors of HBI. Physical activity, both its current level and the level undertaken in the past, as well as the body mass index (BMI) do not determine HBI. In the regression model, physical activity is significantly associated with male gender, past sports activity and a lower BMI level. CONCLUSIONS: Research indicates neglect in the general area of health behaviors among men, while among women, physical activity needs to be more widely popularized. The teacher education system should be more focused on the development of self-development competencies in the context of health-promoting behaviors. Med Pr Work Health Saf. 2024;75(4):355-365.

Asunto(s)

Ejercicio Físico , Conductas Relacionadas con la Salud , Educación y Entrenamiento Físico , Maestros , Estudiantes , Humanos , Femenino , Masculino , Adulto , Estudiantes/psicología , Estudiantes/estadística & datos numéricos , Polonia , Maestros/psicología , Encuestas y Cuestionarios , Persona de Mediana Edad , Adulto Joven , Promoción de la Salud

RESUMEN

Obesity is a complex disease with numerous health complications, influenced by factors such as genetics, lifestyle, mental health, societal impact, economic status, comorbidities, and treatments. This multicenter study included adults aged ≥35 years referred to a CVD prevention program, where sociodemographic data, anthropometric examinations, laboratory tests, and HLPCQ responses were collected. The study analyzed 1044 patients with a mean age of 47.9 years. Among them, 22.2% (232 patients) were diagnosed with obesity. These patients exhibited higher blood pressure, non-HDL cholesterol, triglycerides, and glucose levels (all p < 0.001). A comparative analysis showed that obese patients had significantly lower scores in healthy dietary choices, dietary harm avoidance, daily routine, organized physical exercise, and overall HLPCQ scores. These results indicate that individuals considered healthy were actually living with obesity and its associated complications. Consequently, family physicians should proactively identify patients at risk of obesity using existing programs. The Polish healthcare system urgently needs systemic solutions, including effective health promotion and the creation of obesity prevention programs at an early stage of adult life. These measures are essential to address the growing obesity epidemic and improve public health outcomes.

Asunto(s)

Obesidad , Atención Primaria de Salud , Humanos , Masculino , Femenino , Persona de Mediana Edad , Obesidad/epidemiología , Polonia/epidemiología , Adulto , Prevalencia , Ejercicio Físico , Anciano

RESUMEN

BACKGROUND: The available data on the relationship between diet/folic acid and congenital heart disease (CHD) are not consistent. This study aimed to investigate the relationship between the intake and supplementation of folic acid and other selected factors in mothers and the risk of congenital heart defects in fetuses. METHODS: A case-control study was conducted. The study group included pregnant women with fetuses from singleton pregnancies with prenatally diagnosed heart defects in the fetus (n = 79) and pregnant women whose course of pregnancy was normal with no heart defects or other developmental anomalies diagnosed in the fetus (n = 121). The patients were diagnosed at a reference center in Poland. The women completed a lifestyle questionnaire and FFQ and precisely described their use of dietary supplements. A univariate logistic regression model was used to evaluate the association between folic acid and selected risk factors and CHD. The association was significant and included such risk factors such as nutritional status, medications taken, smoking, and alcohol consumption. Additionally, the time of starting folic acid supplementation turned out to be statistically significant. The reference period of supplementation was the period before pregnancy. RESULTS: Lack of supplementation increases the risk of heart defects in children by more than four times compared to supplementation before pregnancy (OR = 4.19; p = 0.0117), whereas supplementation beyond the eighth week of gestation increases the risk almost threefold (OR = 2.90; p = 0.0474). The presence of congenital defects in the family is also an important factor. CONCLUSIONS: A history of congenital heart defects or other defects, lack of periconceptional folic acid supplementation, and lack of dietary supplementation before pregnancy were associated with congenital heart defects in the fetus. Place of residence, parents' education, lifestyle habits such as smoking and alcohol consumption, nutritional status before pregnancy, and mother's diseases did not show a significant relationship with congenital heart defects in the children. There is an urgent need to develop preventive strategies and conduct extensive public education.

Asunto(s)

Suplementos Dietéticos , Ácido Fólico , Cardiopatías Congénitas , Humanos , Ácido Fólico/administración & dosificación , Femenino , Cardiopatías Congénitas/epidemiología , Embarazo , Factores de Riesgo , Estudios de Casos y Controles , Adulto , Polonia/epidemiología , Estado Nutricional

RESUMEN

Cleft lip and/or palate (CL/P) are the most common congenital anomalies in the craniofacial region, leading to morphological and functional disruptions in the facial region. Their etiology involves genetic and environmental factors, with genetics playing a crucial role. This study aimed to investigate the association of four single nucleotide polymorphisms (SNPs)-rs987525, rs590223, rs522616, and rs4714384-with CL/P in the Polish population. We analyzed DNA samples from 209 individuals with CL/P and 418 healthy controls. The impact of SNPs on the presence of CL/P was assessed using multivariate logistic regression. Significant associations were found with rs987525. Specifically, the AC genotype was linked to an increased CL/P risk (odds ratio [OR] = 1.95, 95% confidence interval [CI]: 1.34-2.83, p < 0.001), while the CC genotype was associated with a decreased risk (OR = 0.46, 95% CI: 0.32-0.67, p < 0.001). Rs4714384 was also significant, with the CT genotype correlated with a reduced risk of CL/P (OR = 0.66, 95% CI: 0.46-0.94, p = 0.011). SNPs rs590223 and rs522616 did not show statistically significant associations. These results underscore the role of rs987525 and rs4714384 in influencing CL/P risk and suggest the utility of genetic screening in understanding CL/P etiology.

Asunto(s)

Labio Leporino , Fisura del Paladar , Predisposición Genética a la Enfermedad , Polimorfismo de Nucleótido Simple , Humanos , Labio Leporino/genética , Labio Leporino/epidemiología , Fisura del Paladar/genética , Fisura del Paladar/epidemiología , Polonia/epidemiología , Femenino , Masculino , Genotipo , Estudios de Casos y Controles , Frecuencia de los Genes , Oportunidad Relativa

RESUMEN

This research studied the phenolic content compared with the antioxidant properties of various O. vulgare (Lamiaceae) cultivars grown in Poland. The research results in this paper indicate that the dominant ingredient in all oregano cultivars was rosmarinic acid, known for its strong antioxidant properties. The highest amounts of rosmarinic acid (87.16 ± 4.03 mg/g dm) were identified in the O. vulgare spp. hirtum (Link) Ietsw. Other metabolites identified in the studied extracts include luteolin O-di-glucuronide-O-di-pentoside (30.79 ± 0.38 mg/g dm in the 'Aureum' cultivar), 4'-O-glucopyranosyl-3', 4'-dihydroxy benzyl-protocatechuate (19.84 ± 0.60 mg/g dm in the 'Margerita' cultivar), and p-coumaroyl-triacetyl-hexoside (25.44 ± 0.18 mg/g dm in the 'Margerita' cultivar). 'Hot & spicy' and 'Margerita' cultivars were characterized by the highest activity in eliminating OH• and O2•- radicals. Extracts from Greek oregano had the highest ability to scavenge DPPH radicals and chelate iron ions. This research has also provided new evidence that oregano has anti-migratory, cytotoxic properties and influences the viability of gastric cancer cells (the highest cytotoxicity was attributed to the 'Hot & spicy' cultivar, which performed the worst in antioxidant properties tests). Extracts from the tested cultivars at a concentration of 0.625% effectively inhibited the growth of S. aureus and P. aeruginosa bacteria. It seems that the oregano grown in Poland is of good quality and can be successfully grown on a large scale if the appropriate use is found.

Asunto(s)

Antioxidantes , Origanum , Extractos Vegetales , Origanum/química , Extractos Vegetales/farmacología , Extractos Vegetales/química , Polonia , Antioxidantes/farmacología , Antioxidantes/química , Humanos , Fenoles/farmacología , Fenoles/análisis , Fenoles/química , Cinamatos/química , Cinamatos/farmacología , Cinamatos/análisis , Antibacterianos/farmacología , Antibacterianos/química , Depsidos/farmacología , Depsidos/química , Ácido Rosmarínico , Línea Celular Tumoral

RESUMEN

The article is devoted to presenting the topic of migration of Ukrainian nationals to Poland. The work makes use of a survey under a project carried out in Polish rural areas and small towns. Seven hundred interviews were held in total. We conducted a quantitative analysis of its results here. The employed methods involve variable frequency distribution. The independence of the features was tested with the non-parametric chi-square test of independence. The association of the investigated variables was determined with Cramér's V. The research shows that the most numerous foreign nationals in the Polish labour market in 2021 were Ukrainians. The positive trend started in 2017. The respondents perceived the migration of Ukrainian nationals to Poland mostly positively, especially regarding seasonal work. They also emphasized that the Ukrainians performed work at variance with their qualifications. Only every fifth participant agreed that migrants took away jobs from Poles. Most of the respondents pointed out that small business owners benefited from employing Ukrainians. The overwhelming majority of the respondents noted an increase in migration from Ukraine after the full-scale invasion and that entire families of Ukrainians were coming to Poland. Nearly half of them agreed that the support system for Ukrainian migrants was a burden on municipal budgets.

Asunto(s)

Población Rural , Migrantes , Ucrania , Polonia , Humanos , Migrantes/estadística & datos numéricos , Migrantes/psicología , Femenino , Masculino , Adulto , Empleo/estadística & datos numéricos , Encuestas y Cuestionarios , Persona de Mediana Edad , Adulto Joven , Emigración e Inmigración

RESUMEN

The studies presented in this paper constitute the first scientific attempt to interpret the manner whereby notched implements made of scapulae were made and used. These implements have been found at numerous European and non-European sites, usually dated to the Neolithic-Early Iron Age (predominantly the Early Bronze Age). Research has examined these products since the beginning of the 20th century, resulting in the development of several hypotheses regarding their functions. This paper presents the analysis results of 41 such artefacts from the early Bronze Age defensive settlement in Bruszczewo (central Poland). This is the largest collection of these products from a single site worldwide. The artefacts were subjected to multi-aspect traceological tests (both technological and functional) using optical, metallographic, and scanning electron microscopes. The residues identified on their surfaces were analysed using optical microscopy and scanning electron microscopy and energy dispersive X-rays spectroscopy. Moreover, the studies reported herein involved extensive experimental research. Consequently, the chain of operations followed in producing these tools was reconstructed and the use-wear traces present on their surfaces were classified; it was determined that these tools were most likely used for threshing cereals but might also have been used for threshing legumes. This is the first proof of threshing in central Europe in the Early Bronze Age and the first scientifically substantiated hypothesis regarding the function of these important artefacts.

Asunto(s)

Arqueología , Grano Comestible , Microscopía Electrónica de Rastreo , Grano Comestible/química , Historia Antigua , Fabaceae/química , Europa (Continente) , Polonia , Humanos , Espectrometría por Rayos X