Asunto(s)
ADN Viral/análisis , Infecciones por Virus de Epstein-Barr/diagnóstico , Pleura/patología , Derrame Pleural/virología , Pleuresia/virología , Anciano , Anciano de 80 o más Años , Estudios de Casos y Controles , Infecciones por Virus de Epstein-Barr/complicaciones , Femenino , Herpesvirus Humano 4/genética , Humanos , Masculino , Persona de Mediana Edad , Derrame Pleural/etiología , Derrame Pleural/patología , Pleuresia/complicaciones , Pleuresia/patología , Estudios Prospectivos , Reacción en Cadena en Tiempo Real de la PolimerasaAsunto(s)
Herpes Simple/complicaciones , Herpes Simple/diagnóstico , Pleuresia/virología , Esclerodermia Sistémica/complicaciones , Aciclovir/uso terapéutico , Anciano , Antivirales/uso terapéutico , Femenino , Herpes Simple/tratamiento farmacológico , Herpes Simple/inmunología , Humanos , Huésped Inmunocomprometido , Pleuresia/tratamiento farmacológico , Pleuresia/inmunologíaRESUMEN
BACKGROUND: Viruses affect the human body in multiple ways producing various disease states. The infections of the pulmonary parenchyma have been well described. However, there has been no current review of the literature pertaining to the pleura. AIM: To review the available literature pertaining to diseases of the pleura that are caused by viral infections. METHODS: A Medline search was performed and available research and review articles relating to viral infections that resulted in pleural effusions, pleural masses, pleural thickening, and pleural nodularity were reviewed. CONCLUSION: There are numerous viruses that cause diseases of the pleura. Pleural effusions and lesions within the pleura are the most common presentation of the disease state. Polymerase chain reaction has the potential to further diagnose viral infections and expand our knowledge base in this field.
Asunto(s)
Pleura/patología , Pleuresia/diagnóstico , Pleuresia/virología , Virosis/diagnóstico , Virosis/virología , Humanos , Técnicas de Diagnóstico Molecular/métodos , Pleuresia/patología , Reacción en Cadena de la Polimerasa , Virosis/patologíaRESUMEN
A study was carried out in 125 farrow-to-finish pig herds to assess the relationships between pathogens involved in respiratory disorders and to relate these findings to clinical signs of respiratory diseases and pneumonia and pleuritis at slaughter. Clinical examination and sampling were carried out on four different batches in each herd (pigs aged 4, 10, 16 and 22 weeks). Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, swine influenza viruses (SIV), porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) were detected by serological or PCR tests. Pneumonia-like gross lesions and pleuritis were scored at the slaughterhouse. The results indicate that the percentage of pigs PCR-positive for PCV2 at 4, 10 and 16 weeks old was associated with the percentage of pigs PCR-positive for M. hyopneumoniae at these ages. On the other hand, the percentage of pigs with antibodies against PRRSV at 10, 16 and 22 weeks was positively correlated with the percentage of pigs seropositive for M. hyopneumoniae at 22 weeks, with the percentage of pigs with antibodies against SIV H1N1 and SIV H1N2 and the percentage of pigs sero-positive for A. pleuropneumoniae serotype 2. The findings also indicate that, within the five studied pathogens, M. hyopneumoniae, PRRSV and SIV H1N1 are the major pathogens involved in pneumonia-like gross lesions even though PCV2 may play a role. A. pleuropneumoniae serotype 2, in association with PRRSV, is significantly associated with extensive pleuritis. Respiratory diseases could be significantly reduced by implementing measures including appropriate management practices to control these pathogens.
Asunto(s)
Actinobacillus pleuropneumoniae/aislamiento & purificación , Circovirus/aislamiento & purificación , Subtipo H1N1 del Virus de la Influenza A/aislamiento & purificación , Mycoplasma hyopneumoniae/aislamiento & purificación , Virus del Síndrome Respiratorio y Reproductivo Porcino/aislamiento & purificación , Enfermedades de los Porcinos/microbiología , Enfermedades de los Porcinos/virología , Infecciones por Actinobacillus/diagnóstico , Infecciones por Actinobacillus/epidemiología , Infecciones por Actinobacillus/veterinaria , Animales , Anticuerpos Antibacterianos/sangre , Anticuerpos Antivirales/sangre , Infecciones por Circoviridae/diagnóstico , Infecciones por Circoviridae/epidemiología , Infecciones por Circoviridae/veterinaria , Estudios Transversales , Francia/epidemiología , Subtipo H1N2 del Virus de la Influenza A , Infecciones por Orthomyxoviridae/diagnóstico , Infecciones por Orthomyxoviridae/epidemiología , Infecciones por Orthomyxoviridae/veterinaria , Pleuresia/epidemiología , Pleuresia/microbiología , Pleuresia/veterinaria , Pleuresia/virología , Pleuroneumonía/epidemiología , Pleuroneumonía/microbiología , Pleuroneumonía/veterinaria , Pleuroneumonía/virología , Síndrome Respiratorio y de la Reproducción Porcina/diagnóstico , Síndrome Respiratorio y de la Reproducción Porcina/epidemiología , Sus scrofa/microbiología , Sus scrofa/virología , Porcinos , Enfermedades de los Porcinos/diagnóstico , Enfermedades de los Porcinos/epidemiologíaRESUMEN
Human parvovirus B19 (PVB19) infection sometimes shows systemic lupus erythematosus (SLE)-like symptoms. We present an SLE patient showing pericarditis and pleuritis with a fever and an acute swelling of extremities 2 months after the fist consultation. Initially, a diagnosis of SLE exacerbation was made. Additional laboratory examination showed positive results for immunoglobulin M (IgM) antibody to PVB19 and PVB19 DNA in serum and pleural effusion at that time. After 1 month, PVB19 DNA in serum and IgM antibody to PVB19 was negative. Based on these findings, a final diagnosis of PVB19 infection in an SLE patient was made. PVB19 infection should be taken into consideration for SLE with acute swelling of the extremities and fever, as these symptoms are often observed in adult cases of PVB19 infection. Steroid pulse therapy rapidly improved these symptoms, and later the dose of steroid was reduced to 5 mg/day of prednisolone. Thus, steroids may be one of the choices for severe and/or rapidly progressive symptoms of pericarditis and pleuritis due to PVB19 infection.
Asunto(s)
Lupus Eritematoso Sistémico/virología , Infecciones por Parvoviridae/complicaciones , Parvovirus B19 Humano/aislamiento & purificación , Pericarditis/virología , Pleuresia/virología , Adulto , Anticuerpos Antivirales/análisis , ADN Viral/análisis , Femenino , Glucocorticoides/uso terapéutico , Humanos , Lupus Eritematoso Sistémico/tratamiento farmacológico , Lupus Eritematoso Sistémico/patología , Infecciones por Parvoviridae/tratamiento farmacológico , Infecciones por Parvoviridae/patología , Parvovirus B19 Humano/genética , Parvovirus B19 Humano/inmunología , Pericarditis/tratamiento farmacológico , Pericarditis/patología , Pleuresia/tratamiento farmacológico , Pleuresia/patología , Prednisolona/uso terapéutico , Quimioterapia por Pulso , Resultado del TratamientoRESUMEN
Pleuropneumonia is a major problem in pig production. At the time of slaughter, chronic pleuritis (CP) developed from pleuropneumonia is a common finding, and breeding for a reduced incidence of CP using marker-assisted selection (MAS) would be advantageous. Before applying MAS, quantitative trait loci (QTL) or markers associated with the prevalence of CP should be identified. In this study, 7470 pigs from crosses between 12 Danish Duroc boars and 604 sows (Danish Landrace × Danish Large White) were evaluated for CP located on the dorso-caudal part of the lungs. Quantitative trait loci were identified within boar families using both a Binomial logistic regression method and a chi-square test of association. Significant QTL for CP were detected on Sus scrofa chromosomes (SSC) 2, 8, 12, 13, 14 and 18 using both methods. One QTL on SSC 8 was also detected across families. For the QTL identified within families, the odds-ratio of having CP was approximately twice as high for the unfavourable allele compared to the favourable one. These QTL and closely linked markers show promise for the development of gene-specific markers associated with a reduced incidence of CP located on the dorso-caudal part of the lungs.
Asunto(s)
Pleuresia/veterinaria , Pleuroneumonía/veterinaria , Sitios de Carácter Cuantitativo , Enfermedades de los Porcinos/genética , Enfermedades de los Porcinos/inmunología , Animales , Cruzamientos Genéticos , Femenino , Pulmón/microbiología , Pulmón/patología , Pulmón/virología , Masculino , Pleuresia/inmunología , Pleuresia/microbiología , Pleuresia/virología , Pleuroneumonía/inmunología , Pleuroneumonía/microbiología , Pleuroneumonía/virología , Sus scrofa , Enfermedades de los Porcinos/microbiología , Enfermedades de los Porcinos/virologíaRESUMEN
Epidemic pleurodynia is seldom reported in Southeast Asia and there has been no report from Taiwan. We conducted a retrospective chart review of children = 18 years of age in the National Taiwan University Hospital from January 1 to December 31, 2005. Epidemic pleurodynia was defined as an acute illness characterized by sharp localized pain over the chest or upper abdomen. Patients with known heart diseases or pulmonary consolidations were excluded. In total, 28 patients met the case definition of epidemic pleurodynia. Coxsackievirus B3 (CB3) was isolated in 15 (60%) of the 25 throat swab specimens. Four (14%) of the 28 patients presented chest wall tenderness and only one (6%) of the 18 patients tested had an elevated creatinine kinase level. Twenty-one (75%) of the 28 patients described pleuritic chest pains and 10 (45%) of the 22 chest radiographies exhibited pulmonary infiltrates or pleural effusions. Six patients were observed with tonsillar exudates and one was confirmed to have a CB3 urinary tract infection. The clinical features and radiological findings suggest that CB3-associated epidemic pleurodynia might be a disease of the pleura and occasionally spreads to nearby tissues, resulting in chest wall myositis, pulmonary infiltrates and myopericarditis.
Asunto(s)
Enterovirus Humano B/aislamiento & purificación , Epidemias , Pleurodinia Epidémica/epidemiología , Pleurodinia Epidémica/virología , Adolescente , Niño , Preescolar , Infecciones por Coxsackievirus/diagnóstico por imagen , Infecciones por Coxsackievirus/epidemiología , Infecciones por Coxsackievirus/fisiopatología , Infecciones por Coxsackievirus/virología , Enterovirus Humano B/clasificación , Enterovirus Humano B/patogenicidad , Femenino , Hospitales Universitarios , Humanos , Lactante , Recién Nacido , Masculino , Faringe/virología , Pleuresia/diagnóstico por imagen , Pleuresia/epidemiología , Pleuresia/fisiopatología , Pleuresia/virología , Pleurodinia Epidémica/diagnóstico por imagen , Pleurodinia Epidémica/fisiopatología , Radiografía , Taiwán/epidemiología , Tonsilitis/epidemiología , Tonsilitis/fisiopatología , Tonsilitis/virología , Infecciones Urinarias/epidemiología , Infecciones Urinarias/fisiopatología , Infecciones Urinarias/virologíaRESUMEN
Two children, 5 and 10 years of age, received unrelated cord blood transplantation (CBT) for malignant lymphoma. Both of them suffered from pleurisy with and without interstitial pneumonitis after transplantation. By the quantitative real-time polymerase chain reaction, human herpesvirus 6 (HHV-6) variant B DNA was detected in pleural effusion. This is the first report of HHV-6-associated pleurisy after hematopoietic stem cell transplantation. HHV-6-associated pleurisy should be considered as a complication after hematopoietic stem cell transplantation even in the absence of pneumonitis. Quantitative polymerase chain reaction is a useful tool for rapid detection of viral DNA, which may facilitate precise diagnosis and appropriate treatment.
Asunto(s)
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Trasplante de Células Madre de Sangre del Cordón Umbilical/efectos adversos , Resistencia a Antineoplásicos , Herpesvirus Humano 6/aislamiento & purificación , Linfoma/tratamiento farmacológico , Pleuresia/virología , Infecciones por Roseolovirus/virología , Niño , Preescolar , ADN Viral/genética , Femenino , Humanos , Linfoma/complicaciones , Masculino , Pleuresia/terapia , Reacción en Cadena de la Polimerasa , Infecciones por Roseolovirus/terapiaAsunto(s)
Anfotericina B/uso terapéutico , Antifúngicos/uso terapéutico , Aspergilosis/tratamiento farmacológico , Hepatitis Viral Humana/tratamiento farmacológico , Itraconazol/uso terapéutico , Sobreinfección/tratamiento farmacológico , Adulto , Aspergilosis/virología , Aspergillus/patogenicidad , Hepatitis Viral Humana/microbiología , Humanos , Masculino , Pleuresia/tratamiento farmacológico , Pleuresia/microbiología , Pleuresia/virologíaRESUMEN
This study describes epidemiologic, etiologic and evaluative aspects of Pleurisy pneumology department of Point "G". From 1st January 1998 to 31 December 2002 was realised a study about hospitalized patients in the department. Pleurisy represented 15; 9% of hospitalizations. The sex Ratio was 2,3 en for men aged of 41 years 55 of pleurisy were located on right. In 60% of cases the liquid was sero-fibrin, purulent in 25% of cases and haemorrhagic in 15%. Tuberculosis was the most frequent etiology with 37% of cases. According to liquid aspect tuberculosis represented 54, 3% of sero-fibrin pleurisy in one hand, on the other 60% of haemorrhagic pleurisy was due to cancer. The serology HIV have been realised on 89 patients and it was positive on 56% of cases. Association pleurisy/HIV tuberculosis etiology represented 56% of cases. Among 369 patients we have counted 100 deaths, 27% and 86% of these death occurred before a month of hospitalization. Even if the prevalence of neoplastic pleurisy increases, tuberculosis still the 1st etiology of pleurisy. It co-infection with HIV is the principal cause of morbidity and mortality.