RESUMEN
O presente estudo teve como objetivo analisar, por meio do exame neurofuncional, a eficácia da cirurgia de neurólise em pacientes com neurite hansênica. Tratou-se de um estudo prospectivo, do tipo descritivo. Teve como universo de estudo a população portadora de neurite hansênica do Estado do Amazonas, tratada na FUAM-AM. Foram selecionados 27 participantes os quais foram triados para cirurgia eletiva de neurólise no período de outubro de 2004 a janeiro de 2005, correspondendo a 64 cirurgias eletivas. Foi realizada uma avaliação neurofuncional pré-operatória compreendendo o teste de força muscular manual, teste de sensibilidade pelos estesiômetros de Semmes-Weinstein, avaliação da dor por meio de escala analógica visual e classificação do grau de incapacidade.A mesma avaliação foi repetida um mês após a cirurgia. Os principais nervos operados foram, em ordem decrescente, medial e ulnar, fibular comum e tibial posterior. A forma clínica mais comum entre os mesmos foi a virchowiana (67 por cento), seguida da dimorfa-virchoviana (19 por cento), tuberculóide (7 por cento) e dimorfa-tuberculóide (7 por cento). Setenta e quatro por cento dos pacientes operados encontravam-se em alta clínica e 26 por cento ainda realizavam tratamento por poliquimioterapia. A principal queixa apresentada foi dor (55 por cento). Em relação ao grau de incapacidade, 70 por cento apresentaram grau I e 30 por cento apresentaram grau II. No pós-operatório, foi relatada melhora da dor em 64 por cento das cirurgias, 30 por cento não apresentaram alteração e 6 por cento apresentaram piora. Cinqüenta e seis por cento dos nervos com comprometimento motor não apresentaram melhora, 32 por cento melhoraram em até um grau e 12 por cento apresentaram piora em até um grau. Trinta e quatro por cento dos pacientes apresentaram melhora da sensibilidade, e 66 por cento se mostraram com quadro inalterado.
The aim of this study was to analyze, through neurofunctional assessment, the effectiveness of the neurolysis surgery in patients with neuritis due to leprosy. It was a prospective and descriptive study. The subjects of this study were the population with neuritis due to leprosy of Amazon state, treated in Fundação Alfredo da Matta (FUAM-AM). 27 participants were selected for elective surgery of neurolysis from October 2004 to January 2005, corresponding to 64 elective surgeries. A preoperative neurofunctional assessment was carried out including manual muscle strength testing, sensibility test using Semmes-Weinstein nylon filaments, pain assessment using a visual analogical scale and classification of rate disability. The same assessment was repeated one month after surgery. The main nerves that underwent surgery were, in decreasing order, medial and ulnar, fibular and posterior tibial. The clinical form more frequently was the lepromatous form (67 percent), following by the lepromatous-borderline (19 percent), tuberculoid (7 percent) and tuberculoid-borderline (7 percent). Seventy four percent of patients had already finished clinical treatment and 26 percent were still using multidrug therapy. Fifty five percent referred pain complaint. Concerning rate disability, 70 percent had level I and 30 percent level II. During the postoperative, patients referred to get better pain sensation in 64 percent of surgeries, 30 percent did not have alteration and 6 percent were worst. Fifty six percent of motor nerves degeneration did not improve, 32 percent improved one level and 12 percent have become worse one level. Thirty four percent of patients referred improvement of sensibility and 66 percent referred no improvement.
Asunto(s)
Cirugía General , Neuritas/clasificación , Neuritas/complicaciones , Neuritas/diagnóstico , Neuritas/terapia , Técnicas de Diagnóstico Quirúrgico/clasificación , Técnicas de Diagnóstico QuirúrgicoRESUMEN
Bombay leprosy project has conducted operational research into cost effective ways of using therapeutic management for prevention of disabilities (POD). The goal of achieving this are broadly divided as 1)prevention of impairments and disabilities(POID) and 2)prevention of worsening of disabilities (POWD). About 33-56% of newly registered leprosy patients already have clinically detectable nerve function impairment (NFI), often no longer amenable to MDT. An analysis of 892 leprosy cases treated with WHO-MD stresses the need to focus attention on leprosy patients...
Asunto(s)
Humanos , Lepra/complicaciones , Lepra/epidemiología , Neuritas/clasificación , Neuritas/complicaciones , Neuritas/prevención & control , Educación del Paciente como Asunto/métodos , Educación en Salud , Medicina EstatalRESUMEN
In conclusion, it may be said that many advances have been made in the diagnosis, treatment and prevention of nerve damage. It is now a well accepted fact that the affinity of M. leprae for Schwann cells and the property of M. leprae to grow in cooler sites of the body have made certain segments of nerve trunks vulnerable. Trauma that supervenes the inflammation and swelling severely aggravates the nerve damage. The reactive phase in all forms of leprosy, the etiology of which is not clearly understood, produces intraneural caseous necrosis in tuberculoid disease and microabscesses in lepromatous disease, causing much irreversible damage to nerves. The steroid treatment that is administered during the reactive phase has helped greatly to stop further damage, although the damage already done to nerves is not always reversible. Preventive measures like detecting the disease before nerve trunks are infected and offering prompt and adequate antileprosy therapy as early as possible have helped to reduce the prevalence of deformities. It is hoped that administering steroids along with antileprosy therapy to prevent active inflammation and or fibrosis of the nerve will reduce the prevalence of nerve damage significantly. Measures which provide rest for the infected nerve to prevent trauma should be explored.
Asunto(s)
Lepra/fisiopatología , Lepra/patología , Neuritas/complicaciones , Neuritas/fisiopatologíaAsunto(s)
Humanos , Eritema Nudoso/complicaciones , Eritema Nudoso/diagnóstico , Eritema Nudoso/etiología , Eritema Nudoso/patología , Eritema Nudoso/terapia , Lepra Dimorfa/complicaciones , Lepra Tuberculoide/complicaciones , Lepra Lepromatosa/complicaciones , Lepra/clasificación , Lepra/complicaciones , Lepra/diagnóstico , Lepra/fisiopatología , Lepra/patología , Lepra/terapia , Neuritas/complicaciones , Neuritas/diagnóstico , Neuritas/etiología , Neuritas/patología , Neuritas/terapia , Leprostáticos/administración & dosificación , Leprostáticos/normas , Leprostáticos/uso terapéutico , Nervios Periféricos/inmunología , Nervios Periféricos/lesiones , Nervios Periféricos/microbiología , Quimioterapia CombinadaRESUMEN
The clinical and neuropathological findings an a patient with "neuritic" leprosy are described. In this rare form of leprosy, skin changes are only minimal or absent anf the diagnosis can be established only by nerve biopsy
Asunto(s)
Lepra Tuberculoide/clasificación , Lepra Tuberculoide/complicaciones , Lepra Tuberculoide/diagnóstico , Lepra Tuberculoide/patología , Neuritas/complicaciones , Neuritas/diagnóstico , Neuritas/etiología , Neuritas/patología , Córnea/metabolismo , Córnea/microbiología , Nervio Sural/anatomía & histología , Nervio Sural/cirugía , Nervio Sural/lesiones , Nervio Sural/microbiología , Nervio Sural/patologíaRESUMEN
A study of the nervous conduction with modern technics has lead to classify the nervous damage according to a new and hsitopathological way which seems more convenient than the Seddon's classification. It gives a better understanding of the hansenian neuritis and reasoned procedures for medical or surgical treatment are discussed
Asunto(s)
Humanos , Compresión Nerviosa/clasificación , Conducción Nerviosa , Neuritas/complicaciones , Neuritas/etiología , Lepra/complicacionesRESUMEN
(Role of temperature, microtraumatisms by elongation or subluxation and canalar stricture.)Cold has a slight aggravating effect on leprosy which is observed in some countries as Iran, South Russia, North India and the Andean cordillera. The subluxation of the ulnar nerve has facilitating effect in the development of the neuritic damage in a limited number of patients. The elongation is important for the production of the ulnar neuritis. The canalar stricture is a major factor causing nerve damage in leprosy. It explains the segmentary localization of the principal damages of the leprous nerves in the proximal areas situated above the tunnels. Intraneural hypertension appears first and is responsible for the swelling of the nerve which gets entraped inside the tunnel. A circulus viciosus is, then, created which maintains and aggravates the intraneural hypertension