RESUMEN
INTRODUCTION: Lipomas are the most common tumors of mesenchymal origin throughout the body. Although they have low incidence in the oral cavity, they surgical approach can be challenging. CASE REPORT: 10-year-old male with a giant lipoma in the buccal and masticator space, an intraoral surgical approach was chosen using by modifying trident technique of Ramírez-Oropeza. DISCUSSION: The main advantages and limitations of this intraoral approach are examined. CONCLUSIONS: An intraoral approach was selected because of less possibility of injuring the facial nerve, better esthetic results and less invasive, obtaining excellent results.
INTRODUCCIÓN: Los lipomas son los tumores de origen mesenquimatoso más comunes en todo el cuerpo. Aunque tienen una baja incidencia en la cavidad oral, su abordaje quirúrgico puede ser un enorme reto. CASO CLÍNICO: Varón de 10 años con un lipoma gigante del espacio geniano y masticador resecado mediante abordaje intraoral modificado de la técnica descrita por Ramírez-Oropeza. DISCUSIÓN: Se describen las principales ventajas y limitaciones de un abordaje intraoral. CONCLUSIONES: Se seleccionó este abordaje intraoral por la menor posibilidad de lesionar el nervio facial, los mejores resultados estéticos y ser menos invasivo, obteniendo excelentes resultados.
Asunto(s)
Neoplasias Faciales , Lipoma , Humanos , Lipoma/cirugía , Masculino , Niño , Neoplasias Faciales/cirugía , Procedimientos Quirúrgicos Orales/métodosRESUMEN
INTRODUCTION: Tranexamic acid (TA) has attracted increased attention among surgical specialties, but its use in plastic surgery is limited. The aim of this study was to assess the efficacy and safety of topical administration of 3% TA solution in reconstructive surgery of the face and scalp after excision of skin cancers. METHODS: a randomized, double-blind, parallel-group clinical trial was conducted in patients aged 18 years or older with malignant skin neoplasms in the face or scalp region (ICD-10 C44.9). The primary outcome was volume of blood loss in the intraoperative and immediate postoperative period. Secondary outcomes included difficult-to-control intraoperative haemorrhage, hematoma, ecchymosis, and other adverse events. RESULTS: of the 54 included patients, 26 were randomised to TA group and 28 to placebo group. The mean blood loss was 11.42ml (SD 6.40, range 8.83-14.01) in the TA group, and 17.6ml (SD 6.22, range 15.19-20.01) in the placebo group, representing a mean decrease of 6.18ml (35.11%) (p=0.001). TA significantly reduced the risk of ecchymosis (RR = 0.046; 95% CI: 0.007-0.323). Only two patients in the placebo group experienced ischemia in the flaps, and one patient in the placebo group experienced tissue necrosis requiring surgical reintervention. There were no surgical wound infections, thromboembolic phenomena, or other adverse events related to TA. CONCLUSIONS: topical TA may reduce intraoperative and immediate postoperative bleeding, with a significantly decreased risk of ecchymosis. There is no evidence of ischemic damage of flaps, systemic thromboembolic complications, or other adverse events.
Asunto(s)
Administración Tópica , Antifibrinolíticos , Neoplasias Faciales , Procedimientos de Cirugía Plástica , Neoplasias Cutáneas , Ácido Tranexámico , Humanos , Ácido Tranexámico/administración & dosificación , Ácido Tranexámico/uso terapéutico , Método Doble Ciego , Masculino , Femenino , Antifibrinolíticos/administración & dosificación , Antifibrinolíticos/uso terapéutico , Neoplasias Cutáneas/cirugía , Procedimientos de Cirugía Plástica/métodos , Procedimientos de Cirugía Plástica/efectos adversos , Persona de Mediana Edad , Neoplasias Faciales/cirugía , Anciano , Pérdida de Sangre Quirúrgica/prevención & control , Adulto , Resultado del TratamientoRESUMEN
BACKGROUND: Surgery is the treatment of choice for patients with basal cell carcinoma (BCC). When surgery is not a choice, only radiotherapy is recommended for patients with high-risk facial BCC. Interferon could be an acceptable therapeutic option for these patients. OBJECTIVE: To evaluate the long-term clinical response to interferon therapy in patients with high-risk facial BCC. METHODS: Patients with high-risk facial BCC were treated with perilesional injections of alpha-2b+ gamma interferons. Those with incomplete clinical response were reevaluated, their residual tumors excised, and declared cured. Patients treated with interferon and those treated with interferon plus surgery were followed for five years. Time to recurrence and the emergence of a new facial BCC were estimated by Kaplan-Meier survival analysis. Adverse events were documented. RESULTS: This study included 195 participants; 143 (73.3%) showed a complete response (95% CI 67.2â80.1). Patients developed recurrence after a mean of 55 months (95% CI 53.8â57.4). The estimated rate of recurrence was 12.3% (95% CI 7.4â17.1). Patients developed a new BCC after a mean of 52.7 months (95% CI 50.4â54.9). The estimated rate for development of a new BCC was 20.0% (95% CI 14.4â25.9). Fifteen (7.7%) patients abandoned the study during follow-up. Adverse events were frequent but moderate or mild; fever and local pain were the most frequent. STUDY LIMITATIONS: Observational cohort design without a control group for comparison. CONCLUSIONS: Perilesional injections of alpha-2b+ gamma interferons in patients with facial high-risk BCC offer a satisfactory cure rate after five years of follow-up with an acceptable safety profile.
Asunto(s)
Carcinoma Basocelular , Neoplasias Faciales , Interferón alfa-2 , Interferón-alfa , Recurrencia Local de Neoplasia , Neoplasias Cutáneas , Humanos , Carcinoma Basocelular/tratamiento farmacológico , Carcinoma Basocelular/patología , Masculino , Femenino , Persona de Mediana Edad , Estudios de Seguimiento , Neoplasias Cutáneas/tratamiento farmacológico , Neoplasias Cutáneas/patología , Anciano , Resultado del Tratamiento , Neoplasias Faciales/tratamiento farmacológico , Interferón alfa-2/uso terapéutico , Interferón alfa-2/administración & dosificación , Interferón-alfa/uso terapéutico , Interferón-alfa/efectos adversos , Interferón-alfa/administración & dosificación , Factores de Tiempo , Adulto , Antineoplásicos/uso terapéutico , Antineoplásicos/efectos adversos , Estimación de Kaplan-Meier , Anciano de 80 o más Años , Interferón gamma/uso terapéutico , Proteínas Recombinantes/uso terapéutico , Proteínas Recombinantes/administración & dosificaciónRESUMEN
O cisto epidérmico é um nódulo subcutâneo benigno, flutuante, com estruturas semelhantes a epiderme. Esse cisto encapsulado é preenchido por material liquido ou pastoso sendo sua localização mais comum em regiões da face, pescoço e tronco. Essas lesões caracterizadas por apresentarem um crescimento lento, indolor, assintomático e pequenos na maioria das vezes, dificilmente ultrapassando 5cm de diâmetro. O tratamento de escolha é a enucleação cirúrgica. Objetivo: O presente trabalho visa relatar um caso clínico de extenso cisto epidérmico na região submentoniana em um paciente do gênero masculino jovem, descrevendo os aspectos clínicos e histopatológicos da lesão e a abordagem realizada, bem como o pós-operatório. Relato de caso: Paciente gênero masculino, 18 anos, compareceu para atendimento com equipe e Bucomaxilofacial, apresentando a queixa de aumento de volume em região submentoniana, com evolução de aproximadamente 02 anos. O paciente foi submetido a exérese da lesão a qual foi realizada a analise anatomopatológica, cujo diagnóstico apresentou-se conclusivo para cisto epidérmico. Conclusão: O diagnóstico diferencial do cisto epidermoide pode variar em muitos casos da região acometida. Ressaltase a importância de um exame clínico minucioso e a necessidade de exames complementares para determinar o diagnóstico correto e, assim, promover um tratamento adequado... (AU)
Epidermoid cysts are benign subepidermal cysts that are fluctuant, presenting structures resembling skin appendages. This encapsulated cyst is filled with liquid or semi-liquid material commonly located on the face, neck and trunk. They are characterised by shows slow growth, painless, asymptomatic and not greater than 5 cm in most cases. The treatment consists of surgical enucleation of the lesion. Objective: To report a case of an extensive epidermoid cyst in the submental region of a young male, describing the approach and its clinical and histopathological aspects with post-op follow-up. Case report: 18 years-old male presents at the Maxillofacial Surgery Department, with the main complaint of swelling in the submental region, for the past 2 years. He underwent surgical excision of the lesion followed by pathological analyse, which returned positive for an epidermal cyst. Conclusion: The differential diagnosis of the epidermoid cyst can vary according to the region in which the lesion develops. It is important to conduct a thorough examination of the patient, and consider complemental tests to attempt the best management for better results... (AU)
El quiste epidérmico es un nódulo subcutáneo flotante benigno con estructuras similares a la epidermis. Este quiste encapsulado está lleno de material líquido o pastoso y se encuentra más comúnmente en la cara, el cuello y el tronco. Estas lesiones se caracterizan por ser de crecimiento lento, indoloras, asintomáticas y de pequeño tamaño en la mayoría de los casos, superando raramente los 5 cm de diámetro. El tratamiento de elección es la enucleación quirúrgica. Objetivo: Este estudio tiene como objetivo reportar un caso clínico de un quiste epidérmico extenso en la región submentoniana en un paciente masculino joven, describiendo los aspectos clínicos e histopatológicos de la lesión y el abordaje realizado, así como el postoperatorio. Reporte de caso: Paciente masculino, de 18 años de edad, acudió para asistencia con el equipo oral y maxilofacial, quejándose de tumefacción en la región submentoniana, con una evolución de aproximadamente 02 años. Al paciente se le realizó exéresis de la lesión, la cual se realizó por análisis anatomopatológico, cuyo diagnóstico fue conclusivo de quiste epidérmico. Conclusión: El diagnóstico diferencial de quiste epidermoide puede variar en muchos casos de la región afectada. Enfatiza la importancia de un examen clínico completo y la necesidad de exámenes complementarios para determinar el diagnóstico correcto y así promover un tratamiento adecuado... (AU)
Asunto(s)
Humanos , Masculino , Adolescente , Neoplasias FacialesRESUMEN
Los hemangiomas infantiles son el resultado de la proliferación de células del endotelio vascular y representan los tumores benignos más frecuentes en la infancia, con una incidencia estimada del 4-10% en bebés caucásicos. Se clasifican según el número, la profundidad y la distribución. Dentro de esta última clasificación se encuentran aquellos denominados segmentarios, que se caracterizan por su distribución extensa en áreas de prolongaciones mesodérmicas embrionarias. Se comunica el caso de una paciente evaluada al mes y medio de vida, con un hemangioma extenso del área mandibular y cuello anterior (hemangioma segmentario de la barba). Se describe la importancia de los estudios complementarios para evaluar el compromiso de órganos subyacentes, para detectar síndromes asociados y definir el tratamiento sobre la base de estos resultados. (AU)
Infantile hemangiomas arise from the proliferation of vascular endothelial cells and represent the most common benign tumors in infancy, with an estimated incidence of 4-10% in Caucasian infants. They vary according to their number, depth, and distribution. Within the latter classification are the so-called segmental ones, which feature an extensive distribution in areas of embryonic mesodermal extensions. We report the case of a patient evaluated at one and a half months of life with an extensive hemangioma of the mandibular area and anterior neck (segmental hemangioma of the beard). We describe the importance of complementary studies for evaluating the involvement of underlying organs, detecting associated syndromes, and defining the treatment based on these findings. (AU)
Asunto(s)
Humanos , Femenino , Lactante , Neoplasias Faciales/diagnóstico , Hemangioma/diagnóstico , Propranolol/administración & dosificación , Neoplasias Faciales/tratamiento farmacológico , Resultado del Tratamiento , Hemangioma/tratamiento farmacológicoRESUMEN
Se presenta un neonato con hemangioma cérvico facial y posterior diagnóstico de hemangioma subglótico. Los hemangiomas en el período neonatal y los primeros meses de vida requieren una atención cuidadosa. Debido a su patrón de crecimiento y la futura aparición de nuevas lesiones, son considerados imprevisibles en esta etapa. Se encontró una fuerte asociación entre los hemangiomas difusos de localización cérvico facial y los hemangiomas sintomáticos de la vía aérea alta. El riesgo está relacionado con el grado de extensión de la afectación cutánea en un área que incluye la piel de la región mandibular, el mentón, el labio inferior y la parte anterior del cuello. Los hemangiomas infantiles requieren tratamiento cuando presentan riesgo vital y alteraciones funcionales, como compromiso de la vía aérea.
This is the case of a newborn with cervical hemangioma and a subsequent diagnosis of subglottic hemangioma. Hemangiomas in neonates and infants require careful attention. Due to their growth pattern and the potential appearance of new lesions, they are considered unpredictable at this stage. A strong link was found between diffuse cervical-facial and symptomatic upper airway hemangiomas. The risk is related to the extent of skin involvement in a given area, which might include the jaw, chin, lower lip, and front of the neck skin. Infant hemangiomas require treatment when they present life-threatening and functional alterations, such as airway compromise.
Relatamos o caso de um recém-nascido com hemangioma cervical com diagnóstico posterior de hemangioma subglótico. Hemangiomas em recém-nascidos e lactentes requerem atenção cuidadosa. Devido ao seu padrão de crescimento e ao potencial aparecimento de novas lesões, são considerados imprevisíveis nessa fase. Uma forte associação foi encontrada entre hemangiomas cervicofaciais difusos e hemangiomas sintomáticos das vias aéreas superiores. O risco está relacionado à extensão do envolvimento da pele da mandíbula, o queixo, o lábio inferior e a pele da frente do pescoço. Os hemangiomas infantis necessitam de tratamento quando apresentam alterações funcionais ou risco de vida, como comprometimento das vias aéreas.
Asunto(s)
Humanos , Femenino , Neoplasias Faciales/diagnóstico , Neoplasias Laríngeas/diagnóstico , Hemangioma/diagnóstico , Propranolol/uso terapéutico , Recien Nacido Prematuro , Neoplasias Faciales/tratamiento farmacológico , Neoplasias Laríngeas/tratamiento farmacológico , Antagonistas Adrenérgicos beta/uso terapéutico , Hemangioma/complicacionesRESUMEN
Las lesiones metastásicas representan hasta un 3 % de los tumores malignos de la glándula tiroides. La mayoría de los casos se originan de tumores de células renales y de pulmón. El abordaje diagnóstico implica una alta sospecha clínica en pacientes con primarios conocidos, sin embargo, puede ser la manifestación inicial de una enfermedad maligna extensa no diagnosticada hasta en un 20 % a 40 % de los pacientes. La biopsia por aguja fina ha demostrado buen rendimiento para el diagnóstico de los nódulos metastásicos. El pronóstico y la opción del tratamiento quirúrgico dependen del control local del primario y del estado de la enfermedad sistémica asociada, por lo tanto, debe ser individualizado. Por lo general, hasta un 80 % de los pacientes con compromiso de la tiroides tienen enfermedad metastásica multiorgánica, y la intención del tratamiento quirúrgico es con fines paliativos para prevenir las complicaciones derivadas de la extensión local de la enfermedad a las estructuras del tracto aerodigestivo superior en el cuello. Se presenta a continuación, una serie de seis casos de pacientes con lesiones metastásicas a glándula tiroides con primarios en riñón, mama y de melanomas
Metastatic lesions represent up to 3% of malignant tumors of the thyroid gland. Most cases originate from lung and renal cell tumors. The diagnostic approach implies a high clinical suspicion in patients with known primaries, however, it can be the initial manifestation of an extensive undiagnosed malignant disease in up to 20% to 40% of patients. Fine-needle biopsy has shown good performance for the diagnosis of metastatic nodules. The prognosis and the option of surgical treatment depend on the local control of the primary condition and the state of the associated systemic disease, therefore it must be individualized. In general, up to 80% of patients with thyroid involvement have multi-organ metastatic disease and surgical treatment is intended to be palliative to prevent complications resulting from local extension of the disease to structures of the upper aerodigestive tract in the neck. A case series of six patients with metastatic lesions to the thyroid gland with primaries in the kidney, breast and melanomas is presented below
Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Neoplasias de la Tiroides/secundario , Neoplasias de la Mama/patología , Neoplasias Faciales/patología , Carcinoma de Células Renales/patología , Carcinoma Ductal de Mama/patología , Extremidad Superior/patología , Neoplasias Renales/patología , Melanoma/patologíaAsunto(s)
Humanos , Masculino , Lactante , Neoplasias Cutáneas/congénito , Neoplasias Faciales/congénito , Miofibromatosis/congénito , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/patología , Neoplasias Faciales/diagnóstico , Neoplasias Faciales/patología , Miofibromatosis/diagnóstico , Miofibromatosis/patologíaAsunto(s)
Coartación Aórtica/diagnóstico , Anomalías del Ojo/diagnóstico , Neoplasias Faciales/diagnóstico , Hemangioma/diagnóstico , Síndromes Neurocutáneos/diagnóstico , Neoplasias Cutáneas/diagnóstico , Neoplasias Faciales/congénito , Femenino , Hemangioma/congénito , Humanos , Lactante , Neoplasias Cutáneas/congénitoAsunto(s)
Neoplasias Faciales/diagnóstico , Leucemia-Linfoma Linfoblástico de Células Precursoras B/diagnóstico , Neoplasias Cutáneas/diagnóstico , Preescolar , Diagnóstico Diferencial , Neoplasias Faciales/patología , Femenino , Frente/patología , Humanos , Leucemia-Linfoma Linfoblástico de Células Precursoras B/patología , Neoplasias Cutáneas/patologíaRESUMEN
OBJECTIVE: To summarize the features of the Merkel cell carcinoma (MCC) and to sistematyze its diagnosis and therapeutic management. METHOD: We performed a literature review in PubMed, obtaining a total of 3,308 articles, selecting 10 for its complete reading and 22 for the reading of the summary according to the content. RESULTS: In none of our patients, the MCC was the first suspected diagnosis. The treatment consisted in surgical excision with tumor free margins and lymphadenectomy. We offered ad-juvant RT which they rejected. They remain disease-free at the present time. CONCLUSIONS: MCC is a rare and aggressive disease which presents as a fast-growing solitary asymptomatic erythematous nodule in those areas of skin which are exposed to sunlight in elderly patients. The main risk factors include radiative ultraviolet, immunosuppression and merkel cell polyomavirus. Surgery is the main loco-regional treatment. Lymph node metastases in the course of the disease is one of the main prognostic factors. If there are no adenopaties, sentinel lymph node biopsy must be done; if there are adenopaties or a positive biopsy, lymphadenectomy is indicated. Radiotherapy is indicated in all stages of disease since it has shown to improve loco-regional control. In distant metastatic disease, immunotherapy and participating in clinical trials are the first choice.
OBJETIVO: Resumir las características del carcinoma de células de Merkel (CCM) y sistematizar su manejo diagnóstico-terapéutico. MÉTODO: Realizamos una búsqueda bibliográfica en PubMed y aparecieron 3,308 artículos, de los que seleccionamos 10 para lectura completa y 22 para lectura del resumen acorde con su contenido. RESULTADOS: En ninguno de nuestros pacientes el CCM fue la primera sospecha diagnóstica. El tratamiento consistió en la extirpación quirúrgica con márgenes libres y linfadenectomía. Se les ofreció radioterapia adyuvante, que rechazaron. Se encuentran libres de enfermedad tras 1 año del tratamiento. CONCLUSIONES: El CCM es una condición rara y agresiva que se presenta como un nódulo eritematoso de rápido crecimiento y asintomático en zonas fotoexpuestas de pacientes añosos. Los principales factores de riesgo son la exposición ultravioleta, la inmunosupresión y el poliomavirus asociado al carcinoma de Merkel (MCPyV, Merkel cell polyomavirus). La cirugía es el pilar fundamental del tratamiento locorregional. La afectación ganglionar en el transcurso de la enfermedad es uno de los principales factores pronósticos. Si no existen adenopatías reconocibles, debe realizarse biopsia selectiva de ganglio centinela; si existen adenopatías o la biopsia es positiva, está indicada la linfadenectomía. La radioterapia adyuvante está indicada en todos los estadios y ha demostrado un mejor control locorregional. En la enfermedad a distancia es de primera elección la inmunoterapia y participar en ensayos clínicos.
Asunto(s)
Carcinoma de Células de Merkel , Neoplasias Faciales , Hallux , Neoplasias Cutáneas , Anciano , Anciano de 80 o más Años , Carcinoma de Células de Merkel/diagnóstico , Carcinoma de Células de Merkel/mortalidad , Carcinoma de Células de Merkel/patología , Carcinoma de Células de Merkel/cirugía , Neoplasias Faciales/diagnóstico , Neoplasias Faciales/mortalidad , Neoplasias Faciales/patología , Neoplasias Faciales/cirugía , Femenino , Humanos , Escisión del Ganglio Linfático , Metástasis Linfática , Masculino , Márgenes de Escisión , Radioterapia Adyuvante , Factores de Riesgo , Biopsia del Ganglio Linfático Centinela , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/mortalidad , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/cirugíaRESUMEN
We report the pathological features of a facial squamous cell carcinoma (SCC) and an abdominal peripheral nerve sheath tumour (PNST) with rhabdomyoblastic differentiation in an aged free-ranging rough-toothed dolphin (Steno bredanensis). The animal was found stranded dead in poor body condition. On external examination, there was a 25 × 7 × 3 cm extensively ulcerated area on the right maxillary region of the rostrum, involving the oral mucocutaneous junction with prominent nodular edges, severe soft tissue loss and extensive maxillary and premaxillary bone lysis. On abdominal dissection, a 5 × 4 × 3.5 cm pale tan to red, raised mass expanded the inner aspect of the right transverse abdominis muscle. Microscopically, the aggressive facial lesion was an acantholytic SCC with extensive osteolysis; there was no evidence of metastasis in the tissues examined. The abdominal mass had cytohistomorphological features compatible with a localized PNST, including whorling, Antoni A and Antoni B areas and Verocay bodies intermixed with rhabdomyoblastic components, as suggested by phosphotungstic acid haematoxylin stain. This neoplasm was locally infiltrative, yet no metastases were observed in the tissues examined. No immunohistochemical investigations could be performed due to lack of tissue availability. Total DNA from the formalin-fixed and paraffin wax-embedded SCC was extracted and tested by polymerase chain reaction for herpesvirus and papillomavirus genetic material. There was no amplification for either of these genera. Other pathological findings observed in this animal were related to the 'live-stranding stress response'. The severity and extent of the facial SCC likely related to anorexia and poor body condition and might have played a role in the stranding and death of this dolphin. These two tumour subtypes add to the relatively uncommon reports of neoplasia in cetaceans. Specifically, these appear to be the first neoplasia records for rough-toothed dolphins, including the first documentation of a PNST with features compatible with rhabdomyoblastic differentiation in a marine mammal.
Asunto(s)
Neoplasias Abdominales/veterinaria , Carcinoma de Células Escamosas/veterinaria , Delfines , Neoplasias Faciales/veterinaria , Neoplasias de la Vaina del Nervio/veterinaria , AnimalesRESUMEN
OBJECTIVE: The aim of this study is to determine the relative frequency, demographic distribution and clinicopathological features of pediatric oral and maxillofacial cancer (POMC). METHODS: Medical records were retrospectively reviewed for all cancer cases diagnosed from 1986 to 2016 affecting patients aged 19 years and younger. Demographic variables, anatomical site, and histopathological diagnoses were collected and analyzed by descriptive statistics. RESULTS: Fifty-five (0.77%) POMCs were found among 7181 pediatric malignancies. Mean age at diagnosis was 8 years and patients aged 5-9 years presented the higher prevalence of malignant tumors (40%). White male patients were more frequently affected (78.18% and 65.45%, respectively). The most common cancer type was lymphomas (52.73%) followed by sarcomas (27.27%) and carcinomas (20%). Burkitt lymphoma (32.73%), rhabdomyosarcoma (14.55%), diffuse large B-cell lymphoma (9.09%), and mucoepidermoid carcinoma (9.09%) were the most common histopathological diagnoses. The main affected anatomical site was the oropharynx (38.18%), followed by salivary glands (30.91%), maxillofacial bone (20%), and oral cavity (10.91%). CONCLUSION: POMC has a low incidence; however, highly aggressive tumors, such as lymphomas and sarcomas, are common in this scenario. A better knowledge about the clinicopathological distribution of POMC may contribute to early diagnosis and improve survival rates.
Asunto(s)
Carcinoma/epidemiología , Neoplasias Faciales/epidemiología , Linfoma/epidemiología , Neoplasias Maxilares/epidemiología , Neoplasias de la Boca/epidemiología , Sarcoma/embriología , Adolescente , Adulto , Factores de Edad , Anciano , Brasil/epidemiología , Carcinoma/patología , Niño , Preescolar , Neoplasias Faciales/patología , Femenino , Humanos , Incidencia , Lactante , Linfoma/patología , Masculino , Neoplasias Maxilares/patología , Persona de Mediana Edad , Neoplasias de la Boca/patología , Prevalencia , Estudios Retrospectivos , Sarcoma/patología , Tasa de Supervivencia , Adulto JovenRESUMEN
Neurofibromas are benign neoplasms of the peripheral nerve sheath, characterized by the proliferation of Schwann cells, perineural cells and endoneural fibroblasts. Their occurrence in the oral and maxillofacial complex is uncommon. This study aimed to evaluate the clinical and histopathological characteristics of neurofibromas of the oral and maxillofacial complex excised at our institution over a 48-year period. Using light microscopy, two previously trained oral pathologists re-evaluated all hematoxylin and eosin slides. From a total of 15,375 cases diagnosed at a referred Oral Pathology Service, 24 cases were diagnosed as neurofibromas. Eighteen neurofibroma patients were female, with a mean age of 39.1 years. Three patients presenting neurofibromas exhibited neurofibromatosis type I. Clinically, most of the lesions presented as asymptomatic nodules, and the most frequent sites were the tongue (n = 6; 25.0%), gingiva (n = 6; 25.0%) and intraosseous maxillary bone region (n = 3; 12.5%). Histopathologically, the lesions were predominantly well delimited, exhibiting interlocking bundles of spindle-shaped cells that usually displayed wavy nuclei, associated with delicate collagen fibers. Thus, knowledge of their clinical and histopathological features by dentists and oral pathologists is essential for the correct diagnosis of these lesions.
Asunto(s)
Neoplasias Faciales/patología , Neoplasias Maxilares/patología , Neoplasias de la Boca/patología , Neurofibroma/patología , Adolescente , Adulto , Anciano , Niño , Preescolar , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto JovenRESUMEN
RESUMEN Introducción: La magnitud de las resecciones de tumores de cabeza y cuello, depende del tamaño tumoral, la adecuación de los márgenes y factores inherentes al paciente. El músculo temporal, constituye una excelente opción para reconstruir defectos de zonas aledañas a su sitio de implantación. Objetivo: Demostrar la versatilidad del colgajo miofascial de temporal para la reconstrucción tras, cirugía oncológica de cabeza y cuello, en el Hospital Provincial Universitario "Camilo Cienfuegos Gorriarán" desde enero de 2017 a diciembre de 2018. Métodos: Se realizó una revisión retrospectiva de los informes operatorios de los casos intervenidos con cirugía oncológica de cabeza y cuello, en el servicio de cirugía maxilofacial; se tomó de muestra a pacientes a los que, se les realizó reconstrucción del defecto quirúrgico, utilizándose colgajo miofascial de temporal. Resultados: Fueron sometidos a reconstrucción, 12 pacientes de forma inmediata, en un solo tiempo quirúrgico. El defecto se presentó mayormente en lesiones de piel. La edad promedio de los pacientes fue 66,2 años. Se observó una distribución equitativa en cuanto a sexo, con 6 pacientes para cada grupo. El seguimiento osciló entre 2 y 20 meses, con una media de 11,25 meses, de los cuales todos los pacientes se encontraban vivos y controlados. Conclusiones: El colgajo temporal continúa siendo una opción válida para la reconstrucción en cirugía oncológica de cabeza y cuello. En la serie revisada no ocurrió necrosis, lo que, lo hace un colgajo muy seguro, con buenos resultados estéticos y funcionales y con buena tolerancia ante los tratamientos oncoespecíficos adyuvantes(AU)
ABSTRACT Introduction: The magnitude of the resections of head and neck tumors depends on the tumor size, the adequacy of the margins and factors inherent to the patient. The temporal muscle is an excellent option for reconstructing defects in areas surrounding its implantation site. Objective: To demonstrate the versatility of the temporal myofascial flap for reconstruction after oncological head and neck surgery, at the "Camilo Cienfuegos Gorriarán" Provincial University Hospital from January 2017 to December 2018. Methods: A retrospective review of the operative reports of the cases intervened with oncological head and neck surgery was performed in the maxillofacial surgery service; A sample was taken from patients who underwent reconstruction of the surgical defect, using a temporal myofascial flap. Results: 12 patients underwent reconstruction immediately, in a single surgical time. The defect occurred mainly in skin lesions. The average age of the patients was 66.2 years. An equitable distribution in terms of sex was observed, with 6 patients for each group. Follow-up ranged from 2 to 20 months, with a mean of 11.25 months, of which all the patients were alive and controlled. Conclusions: The temporary flap continues to be a valid option for reconstruction in head and neck cancer surgery. Necrosis did not occur in the revised series, which makes it a very safe flap, with good aesthetic and functional results and with good tolerance to adjuvant oncospecific treatments(AU)
Asunto(s)
Humanos , Masculino , Femenino , Anciano , Colgajos Quirúrgicos/efectos adversos , Neoplasias Faciales/cirugía , Procedimientos de Cirugía Plástica/métodos , Estudios RetrospectivosRESUMEN
ABSTRACT Lipoma is a usually painless benign adipose tumor. Nevertheless, it can cause compression of adjacent structures, depending on its location. Mucoceles are benign cystic lesions in the frontal-ethmoidal region, caused by chronic obstruction of the paranasal sinus and consequent inflammatory processes. The increase of mucocele diameter caused by inflammation often results in bony degradation and reabsorption, increasing pressure on adjacent structures, including the orbit and the base of the skull, leading to possibly serious consequences. Here we report a case of lipoma mimicking a frontal mucocele, managed surgically at the Ophthalmological Hospital of Anapolis.
RESUMO O lipoma é um tumor do tecido adiposo de caráter benigno, usualmente indolor, porém que pode gerar compressão de estruturas adjacentes, dependendo da sua localização. A mucocele consiste em uma lesão cística de caráter benigno, na região fronto-etmoidal, devido à obstrução crônica dos óstios dos seios paranasais e consequente processo inflamatório. O aumento do diâmetro da mucocele por inflamação muitas vezes causa degradação e reabsorção ósseas, o que pode elevar a pressão em estruturas adjacentes como órbita e base de crânio, causando intercorrências possivelmente graves. Neste estudo relatamos um caso de lipoma simulando mucocele frontal, com propedêutica cirúrgica.
Asunto(s)
Humanos , Femenino , Anciano , Neoplasias Faciales/cirugía , Lipoma/cirugía , Mucocele , Órbita/cirugía , Seno FrontalRESUMEN
El Tricoepitelioma Múltiple Familiar (TMF) constituye una rara enfermedad autosómica dominante, se caracteriza por la aparición de múltiples pápulas color piel, monomorfas, simétricas, ubicadas en la región central de la cara. El diagnóstico es histopatológico, donde se encuentran tricoepiteliomas, los cuales son neoplasias anexiales benignas que se originan en los folículos pilosos. La condición es de comportamiento indolente, pero con una importante repercusión estética y de difícil manejo. Al ser esta una entidad poco frecuente, el objetivo de este artículo es actualizar los aspectos más relevantes de esta enfermedad. Se presenta el caso de una paciente de 23 años con lesiones faciales típicas en quien se confirmó el diagnostico de TMF
Familial Multiple Trichoepithelioma (FMT) is a rare autosomal dominant disease, characte-rized by the appearance of multiple papules of skin color, monomorphic, symmetrical and located in the central region of the face. The diagnosis is based on histopathological features of trichoepitheliomas, which are benign adnexal neoplasms that originate in the hair follicles. The condition has an indolent behavior but it has an important aesthetic repercussion and it's difficult to treat. As this is a rare entity, the objective of this article is to update the most relevant aspects of this disease. We present the case of a 23 year old patient with typical facial lesions in whom the diagnosis of FMT was confirmed.